Unchain My Heart: Integrins at the Basis of iPSC Cardiomyocyte Differentiation

Integrin diversity brings specificity in mechanotransduction

(2018) Shailaja Seetharaman et al.   BIOLOGY OF THE CELL

Mechanotransduction of human pluripotent stem cells cultivated on tunable cell-derived extracellular matrix

(2018) In Gul Kim et al.   BIOMATERIALS

Orientations of Cells on Compliant Substrates under Biaxial Stretches: A Theoretical Study

(2018) Guang-Kui Xu et al.   BIOPHYSICAL JOURNAL

Identification of integrin heterodimers functioning on the surface of undifferentiated porcine primed embryonic stem cells

(2018) Hwa-Young Kim et al.   CELL BIOLOGY INTERNATIONAL

Extracellular calcium regulates the adhesion and migration of osteoclast via integrin αv β3 / Rho A/Cytoskeleton signaling

(2018) Bilu Xiang et al.   CELL BIOLOGY INTERNATIONAL

A Photoactivatable α5 β1 -Specific Integrin Ligand

(2018) Roshna V. Nair et al.   CHEMBIOCHEM

Evolution of mechanotransduction via YAP/TAZ in animal epithelia

(2018) Ahmed Elbediwy et al.   CURRENT OPINION IN CELL BIOLOGY

Effect of geometrical constraints on human pluripotent stem cell nuclei in pluripotency and differentiation

(2018) Eleonora Grespan et al.   Integrative Biology

Fluid flow modulates electrical activity in cardiac hERG potassium channels

(2018) Samrat Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aortic valve cell seeding into decellularized animal pericardium by perfusion-assisted bioreactor

(2018) Francesco Amadeo et al.   Journal of Tissue Engineering and Regenerative Medicine

Investigation of human iPSC-derived cardiac myocyte functional maturation by single cell traction force microscopy

(2018) Matthew Wheelwright et al.   PLoS One

Surface functionalization of polyurethane scaffolds mimicking the myocardial microenvironment to support cardiac primitive cells

(2018) Monica Boffito et al.   PLoS One

The Application of Induced Pluripotent Stem Cells in Cardiac Disease Modeling and Drug Testing

(2018) Lingqun Ye et al.   Journal of Cardiovascular Translational Research

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

(2018) Stéphanie Kilens et al.   Nature Communications

A Single-Step Surface Modification of Electrospun Silica Nanofibers Using a Silica Binding Protein Fused with an RGD Motif for Enhanced PC12 Cell Growth and Differentiation

(2018) Wen Chen et al.   Materials

Integrin Clustering Matters: A Review of Biomaterials Functionalized with Multivalent Integrin-Binding Ligands to Improve Cell Adhesion, Migration, Differentiation, Angiogenesis, and Biomedical Device Integration

(2018) Fatemeh Karimi et al.   Advanced Healthcare Materials

Designing well-defined photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells

(2018) Elisa M. Ovadia et al.   Biomaterials Science

Strategies for directing cells into building functional hearts and parts

(2018) Mahboubeh Jafarkhani et al.   Biomaterials Science

Building a Total Bioartificial Heart: Harnessing Nature to Overcome the Current Hurdles

(2018) Doris A. Taylor et al.   ARTIFICIAL ORGANS

Nanotopography-responsive myotube alignment and orientation as a sensitive phenotypic biomarker for Duchenne Muscular Dystrophy

(2018) Bin Xu et al.   BIOMATERIALS

Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling

(2018) Rosaria Santoro et al.   BIOMATERIALS

Rapid 3D bioprinting of decellularized extracellular matrix with regionally varied mechanical properties and biomimetic microarchitecture

(2018) Xuanyi Ma et al.   BIOMATERIALS

Y-27632 preconditioning enhances transplantation of human-induced pluripotent stem cell-derived cardiomyocytes in myocardial infarction mice

(2018) Meng Zhao et al.   CARDIOVASCULAR RESEARCH

Cardiac fibrosis in regenerative medicine: destroy to rebuild

(2018) Gianluca Lorenzo Perrucci et al.   Journal of Thoracic Disease

Matrix stiffness modulates the differentiation of neural crest stem cells in vivo

(2018) Yiqian Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of integrin β1 in the heterogeneity of human embryonic stem cells culture

(2018) Ade Kallas-Kivi et al.   Biology Open

β1 integrin–dependent Rac/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2/merlin

(2017) Hiba Sabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of substrate biomechanics in controlling (stem) cell fate: Implications in regenerative medicine

(2017) Laura Macri-Pellizzeri et al.   Journal of Tissue Engineering and Regenerative Medicine

Effects of substrate stiffness and actomyosin contractility on coupling between force transmission and vinculin–paxillin recruitment at single focal adhesions

(2017) Dennis W. Zhou et al.   MOLECULAR BIOLOGY OF THE CELL

Receptor-mediated cell mechanosensing

(2017) Yunfeng Chen et al.   MOLECULAR BIOLOGY OF THE CELL

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

(2017) Michiko Mandai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Feeling the right force: How to contextualize the cell mechanical behavior in physiologic turnover and pathologic evolution of the cardiovascular system

(2017) Maurizio Pesce et al.   PHARMACOLOGY & THERAPEUTICS

Electro-mechanical conditioning of human iPSC-derived cardiomyocytes for translational research

(2017) Katharina Kroll et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Epigenetic Erasing and Pancreatic Differentiation of Dermal Fibroblasts into Insulin-Producing Cells are Boosted by the Use of Low-Stiffness Substrate

(2017) Georgia Pennarossa et al.   Stem Cell Reviews and Reports

Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling

(2017) Oscar J. Abilez et al.   STEM CELLS

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

Effects of mechanical stimulation on the reprogramming of somatic cells into human-induced pluripotent stem cells

(2017) Young Mi Kim et al.   Stem Cell Research & Therapy

Predictive model identifies key network regulators of cardiomyocyte mechano-signaling

(2017) Philip M. Tan et al.   PLoS Computational Biology

Bioinspired onion epithelium-like structure promotes the maturation of cardiomyocytes derived from human pluripotent stem cells

(2017) Cong Xu et al.   Biomaterials Science

Surface-modified polymers for cardiac tissue engineering

(2017) Ambigapathi Moorthi et al.   Biomaterials Science

Phase I Clinical Trial of Autologous Stem Cell–Sheet Transplantation Therapy for Treating Cardiomyopathy

(2017) Shigeru Miyagawa et al.   Journal of the American Heart Association

Epigenetic Erasing and Pancreatic Differentiation of Dermal Fibroblasts into Insulin-Producing Cells are Boosted by the Use of Low-Stiffness Substrate

(2017) Georgia Pennarossa et al.   Stem Cell Reviews and Reports

Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies

(2017) Giulio Abagnale et al.   Stem Cell Reports

Decellularized Matrices As Cell-Instructive Scaffolds to Guide Tissue-Specific Regeneration

(2017) Kevin P. Robb et al.   ACS Biomaterials-Science & Engineering

Decellularized Matrices As Cell-Instructive Scaffolds to Guide Tissue-Specific Regeneration

(2017) Kevin P. Robb et al.   ACS Biomaterials Science & Engineering

Bio-scaffolds in organ-regeneration: Clinical potential and current challenges

(2017) S. Yesmin et al.   Current Research in Translational Medicine

Nanotopography-Induced Structural Anisotropy and Sarcomere Development in Human Cardiomyocytes Derived from Induced Pluripotent Stem Cells

(2016) Daniel Carson et al.   ACS Applied Materials & Interfaces

High-Frequency Mechanostimulation of Cell Adhesion

(2016) Laith F. Kadem et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts

(2016) Elena Garreta et al.   BIOMATERIALS

Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac TissueClinical Perspective

(2016) Jia-Ling Ruan et al.   CIRCULATION

Mechanotransduction and nuclear function

(2016) David M Graham et al.   CURRENT OPINION IN CELL BIOLOGY

Plasticity in the Adult: How Should the Waddington Diagram Be Applied to Regenerating Tissues?

(2016) Jayaraj Rajagopal et al.   DEVELOPMENTAL CELL

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

(2016) Sirio Dupont   EXPERIMENTAL CELL RESEARCH

Use of protein-engineered fabrics to identify design rules for integrin ligand clustering in biomaterials

(2016) Patrick L. Benitez et al.   Integrative Biology

Elastic, silk-cardiac extracellular matrix hydrogels exhibit time-dependent stiffening that modulates cardiac fibroblast response

(2016) Whitney L. Stoppel et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Nanowires and Electrical Stimulation Synergistically Improve Functions of hiPSC Cardiac Spheroids

(2016) Dylan J. Richards et al.   NANO LETTERS

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart

(2016) Sofia Hirth et al.   PLoS One

Inhibition of Focal Adhesion Kinase Signaling by Integrin α6β1 Supports Human Pluripotent Stem Cell Self-Renewal

(2016) Luis G. Villa-Diaz et al.   STEM CELLS

Selective binding and lateral clustering of α5β1 and αvβ3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly

(2016) Viktoria Schaufler et al.   Cell Adhesion & Migration

Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity

(2016) Takayuki Kishi et al.   Oncotarget

Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single-Use Stirred Tank Bioreactors

(2016) Christina Kropp et al.   Stem Cells Translational Medicine

Biological Effects of Culture Substrates on Human Pluripotent Stem Cells

(2016) Yohei Hayashi et al.   Stem Cells International

Enhanced Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte Maturation Using a Dual Microgradient Substrate

(2016) E. Huethorst et al.   ACS Biomaterials-Science & Engineering

Enhanced Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte Maturation Using a Dual Microgradient Substrate

(2016) E. Huethorst et al.   ACS Biomaterials Science & Engineering

Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α5β1 integrin engagement

(2016) Maryam Riaz et al.   Scientific Reports

Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation

(2015) Yi-Chin Toh et al.   BIOMATERIALS

Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes

(2015) Young Wook Chun et al.   BIOMATERIALS

Acellular human heart matrix: A critical step toward whole heart grafts

(2015) Pedro L. Sánchez et al.   BIOMATERIALS

Bioengineering Human Myocardium on Native Extracellular MatrixNovelty and Significance

(2015) Jacques P. Guyette et al.   CIRCULATION RESEARCH

Networking in the nucleus: a spotlight on LEM-domain proteins

(2015) Lacy J Barton et al.   CURRENT OPINION IN CELL BIOLOGY

Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status

(2015) Young Wook Chun et al.   JOURNAL OF BIOMECHANICS

Feasibility of pig and human-derived aortic valve interstitial cells seeding on fixative-free decellularized animal pericardium

(2015) Rosaria Santoro et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Substrate Coupling Strength of Integrin-Binding Ligands Modulates Adhesion, Spreading, and Differentiation of Human Mesenchymal Stem Cells

(2015) Chun Kit K. Choi et al.   NANO LETTERS

Silicon Nanowire-Induced Maturation of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

(2015) Yu Tan et al.   NANO LETTERS

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

(2015) Alexandre J. S. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Regulatory Network Involving β-Catenin, e-Cadherin, PI3k/Akt, and Slug Balances Self-Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling

(2015) Tyng-Shyan Huang et al.   STEM CELLS

Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

(2015) Hongwei Chen et al.   Nature Communications

Extracellular matrix: A dynamic microenvironment for stem cell niche

(2014) Francesca Gattazzo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

Engineering Adolescence

(2014) Xiulan Yang et al.   CIRCULATION RESEARCH

Mechanosensors in integrin signaling: The emerging role of p130Cas

(2014) Radoslav Janoštiak et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Microscale technologies for regulating human stem cell differentiation

(2014) Elisa Cimetta et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Polyglycolic acid sheet with fibrin glue potentiates the effect of a fibrin-based haemostat in cardiac surgery

(2014) Hirofumi Kasahara et al.   Journal of Cardiothoracic Surgery

The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture

(2014) Natalie E. Cain et al.   JOURNAL OF CELL BIOLOGY

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate

(2014) Matthew J. Dalby et al.   NATURE MATERIALS

Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink

(2014) Falguni Pati et al.   Nature Communications

High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry

(2014) Subarna Bhattacharya et al.   Jove-Journal of Visualized Experiments

Cell shape-dependent early responses of fibroblasts to cyclic strain

(2013) Neha Gadhari et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Combined Effects of PEG Hydrogel Elasticity and Cell-Adhesive Coating on Fibroblast Adhesion and Persistent Migration

(2013) Dimitris Missirlis et al.   BIOMACROMOLECULES

Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias

(2013) Jiaxian Wang et al.   BIOMATERIALS

Collagen/β1 integrin interaction is required for embryoid body formation during cardiogenesis from murine induced pluripotent stem cells

(2013) Di Zeng et al.   BMC CELL BIOLOGY

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast

(2013) Yun-Shen Chan et al.   Cell Stem Cell

In Vivo Differentiation of Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2013) Tao Yu et al.   CIRCULATION JOURNAL

Inactivation of Serum Response Factor Contributes To Decrease Vascular Muscular Tone and Arterial Stiffness in Mice

(2013) Guillaume Galmiche et al.   CIRCULATION RESEARCH

Mechanosensitivity and compositional dynamics of cell–matrix adhesions

(2013) Herbert B Schiller et al.   EMBO REPORTS

Robust pluripotent stem cell expansion and cardiomyocyte differentiation via geometric patterning

(2013) Frank B. Myers et al.   Integrative Biology

Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

(2013) Despina Soteriou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic Mechanical Reinforcement of Integrin–Ligand Interactions

(2013) Fang Kong et al.   MOLECULAR CELL

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

Kindlin-1 Regulates Integrin Dynamics and Adhesion Turnover

(2013) Coert Margadant et al.   PLoS One

Integrin-Specific Control of Focal Adhesion Kinase and RhoA Regulates Membrane Protrusion and Invasion

(2013) Patricia Costa et al.   PLoS One

Rigid microenvironments promote cardiac differentiation of mouse and human embryonic stem cells

(2013) Armin Arshi et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Extracellular Matrix-Mediated Differentiation of Human Embryonic Stem Cells: Differentiation to Insulin-Secreting Beta Cells

(2013) Karthikeyan Narayanan et al.   TISSUE ENGINEERING PART A

Polyurethane-based scaffolds for myocardial tissue engineering

(2013) V. Chiono et al.   Interface Focus

Cardiac Fibroblast-Derived Extracellular Matrix (Biomatrix) as a Model for the Studies of Cardiac Primitive Cell Biological Properties in Normal and Pathological Adult Human Heart

(2013) Clotilde Castaldo et al.   Biomed Research International

Assessing the responses of cellular proteins induced by hyaluronic acid-modified surfaces utilizing a mass spectrometry-based profiling system: Over-expression of CD36, CD44, CDK9, and PP2A

(2012) Ming-Hui Yang et al.   ANALYST

Mechanical Regulation of Nuclear Structure and Function

(2012) Rui P. Martins et al.   Annual Review of Biomedical Engineering

Filamins in Mechanosensing and Signaling

(2012) Ziba Razinia et al.   Annual Review of Biophysics

p130Cas-dependent actin remodelling regulates myogenic differentiation

(2012) Keiko Kawauchi et al.   BIOCHEMICAL JOURNAL

From Mechanical Force to RhoA Activation

(2012) Elizabeth C. Lessey et al.   BIOCHEMISTRY

The significance of integrin ligand nanopatterning on lipid raft clustering in hematopoietic stem cells

(2012) Eva Altrock et al.   BIOMATERIALS

Pull and push: Talin activation for integrin signaling

(2012) Jia-huai Wang   CELL RESEARCH

Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells to Cardiomyocytes

(2012) Christine L. Mummery et al.   CIRCULATION RESEARCH

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

(2012) J.-S. Mo et al.   GENES & DEVELOPMENT

Talin activates integrins by altering the topology of the β transmembrane domain

(2012) Chungho Kim et al.   JOURNAL OF CELL BIOLOGY

Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension

(2012) S. R. Coyer et al.   JOURNAL OF CELL SCIENCE

Inhibition of Integrin  2 1 Ameliorates Glomerular Injury

(2012) C. M. Borza et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions

(2012) Jeanette Beers et al.   Nature Protocols

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

Insights into the Role of Focal Adhesion Modulation in Myogenic Differentiation of Human Mesenchymal Stem Cells

(2012) Haiyang Yu et al.   STEM CELLS AND DEVELOPMENT

Bioprocess Development for Mass Production of Size-Controlled Human Pluripotent Stem Cell Aggregates in Stirred Suspension Bioreactor

(2012) Saeed Abbasalizadeh et al.   TISSUE ENGINEERING PART C-METHODS

A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation

(2012) Zhonghan Li et al.   Nature Communications

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Evaluation of the Biocompatibility of PLACL/Collagen Nanostructured Matrices with Cardiomyocytes as a Model for the Regeneration of Infarcted Myocardium

(2011) Shayanti Mukherjee et al.   ADVANCED FUNCTIONAL MATERIALS

Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function

(2011) Brian Liau et al.   BIOMATERIALS

Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs

(2011) Norikatsu Miyoshi et al.   Cell Stem Cell

Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2synthesis

(2011) Kyle R Legate et al.   EMBO JOURNAL

Nanolithographic Control of the Spatial Organization of Cellular Adhesion Receptors at the Single-Molecule Level

(2011) Mark Schvartzman et al.   NANO LETTERS

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Modelling the long QT syndrome with induced pluripotent stem cells

(2011) Ilanit Itzhaki et al.   NATURE

A Universal System for Highly Efficient Cardiac Differentiation of Human Induced Pluripotent Stem Cells That Eliminates Interline Variability

(2011) Paul W. Burridge et al.   PLoS One

Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity

(2011) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays

(2010) Jing Yang et al.   BIOMATERIALS

Actin-Myosin Contractility Is Responsible for the Reduced Viability of Dissociated Human Embryonic Stem Cells

(2010) Guokai Chen et al.   Cell Stem Cell

Molecular Pathway and Cell State Responsible for Dissociation-Induced Apoptosis in Human Pluripotent Stem Cells

(2010) Masatoshi Ohgushi et al.   Cell Stem Cell

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Specificities of β1 integrin signaling in the control of cell adhesion and adhesive strength

(2010) Myriam Régent et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Vinculin, an adapter protein in control of cell adhesion signalling

(2010) Alex Carisey et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

(2010) Ana M. Pasapera et al.   JOURNAL OF CELL BIOLOGY

Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions

(2010) Dong Li et al.   JOURNAL OF CELL BIOLOGY

The switchable integrin adhesome

(2010) R. Zaidel-Bar et al.   JOURNAL OF CELL SCIENCE

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Filamins in cell signaling, transcription and organ development

(2010) Alex-Xianghua Zhou et al.   TRENDS IN CELL BIOLOGY

Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche

(2009) Seung Tae Lee et al.   BIOMATERIALS

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Molecules that Promote or Enhance Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells

(2009) Bo Feng et al.   Cell Stem Cell

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Characterization of integrin engagement during defined human embryonic stem cell culture

(2009) Ying Meng et al.   FASEB JOURNAL

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Microwell-mediated control of embryoid body size regulates embryonic stem cell fate via differential expression of WNT5a and WNT11

(2009) Y.-S. Hwang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress

(2009) M. B. Asparuhova et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Analysis of the distinct functions of growth factors and tissue culture substrates necessary for the long-term self-renewal of human embryonic stem cell lines

(2009) Melissa A. Baxter et al.   Stem Cell Research

Roles of Integrins in Human Induced Pluripotent Stem Cell Growth on Matrigel and Vitronectin

(2009) Teisha J. Rowland et al.   STEM CELLS AND DEVELOPMENT

Becoming stable and strong: The interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation

(2009) Christoph Möhl et al.   CELL MOTILITY AND THE CYTOSKELETON

Recombinant human laminin isoforms can support the undifferentiated growth of human embryonic stem cells

(2008) Takamichi Miyazaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Formins in cell signaling

(2008) Kevin G. Young et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Production of arrays of cardiac and skeletal muscle myofibers by micropatterning techniques on a soft substrate

(2008) Elisa Cimetta et al.   BIOMEDICAL MICRODEVICES

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

(2008) A. J. Engler et al.   JOURNAL OF CELL SCIENCE

Actin stress fibers transmit and focus force to activate mechanosensitive channels

(2008) Kimihide Hayakawa et al.   JOURNAL OF CELL SCIENCE

Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies

(2008) B. Valamehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microwell array system for stem cell culture

(2007) Hannes-Christian Moeller et al.   BIOMATERIALS