Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

(2014) Yasuhiro Takashima et al.   CELL

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

(2014) Thorold W. Theunissen et al.   Cell Stem Cell

NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program

(2014) Hannah T. Stuart et al.   CURRENT BIOLOGY

Derivation of naive human embryonic stem cells

(2014) C. B. Ware et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells

(2014) Irène Aksoy et al.   Nature Communications

Platform for Induction and Maintenance of Transgene-free hiPSCs Resembling Ground State Pluripotent Stem Cells

(2014) Bahram Valamehr et al.   Stem Cell Reports

virtualArray: a R/bioconductor package to merge raw data from different microarray platforms

(2013) Andreas Heider et al.   BMC BIOINFORMATICS

Induction of a Human Pluripotent State with Distinct Regulatory Circuitry that Resembles Preimplantation Epiblast

(2013) Yun-Shen Chan et al.   Cell Stem Cell

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

(2013) Gabriella Ficz et al.   Cell Stem Cell

Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells

(2013) Ehsan Habibi et al.   Cell Stem Cell

Identification of the missing pluripotency mediator downstream of leukaemia inhibitory factor

(2013) Graziano Martello et al.   EMBO JOURNAL

Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1

(2013) Shoudong Ye et al.   EMBO JOURNAL

Gbx2, a LIF/Stat3 target, promotes reprogramming to and retention of the pluripotent ground state

(2013) C.-I. Tai et al.   JOURNAL OF CELL SCIENCE

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells

(2013) Céline Vallot et al.   NATURE GENETICS

Naive pluripotency is associated with global DNA hypomethylation

(2013) Harry G Leitch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

(2012) Shila Mekhoubad et al.   Cell Stem Cell

Accessing naïve human pluripotency

(2012) Alejandro De Los Angeles et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency

(2012) Anouk L. van Oosten et al.   Nature Communications

Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development

(2011) R. Vassena et al.   DEVELOPMENT

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

(2011) Ikuhiro Okamoto et al.   NATURE

Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling

(2011) Hongcang Gu et al.   Nature Protocols

Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency

(2010) Jian Yang et al.   Cell Stem Cell

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Oct4 and LIF/Stat3 Additively Induce Krüppel Factors to Sustain Embryonic Stem Cell Self-Renewal

(2009) John Hall et al.   Cell Stem Cell

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

Klf4 reverts developmentally programmed restriction of ground state pluripotency

(2009) G. Guo et al.   DEVELOPMENT

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells

(2009) Siqin Bao et al.   NATURE

Novel STAT3 Target Genes Exert Distinct Roles in the Inhibition of Mesoderm and Endoderm Differentiation in Cooperation with Nanog

(2009) Pierre-Yves Bourillot et al.   STEM CELLS

Krüppel-like factor 5 Is Essential for Blastocyst Development and the Normal Self-Renewal of Mouse ESCs

(2008) Masatsugu Ema et al.   Cell Stem Cell

Klf5 is involved in self-renewal of mouse embryonic stem cells

(2008) S. Parisi et al.   JOURNAL OF CELL SCIENCE

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Derivation and Cloning of a Novel Rhesus Embryonic Stem Cell Line Stably Expressing Tau-Green Fluorescent Protein

(2008) Florence Wianny et al.   STEM CELLS