Microscale technologies for regulating human stem cell differentiation

Physiologically relevant organs on chips

(2013) Kyungsuk Yum et al.   Biotechnology Journal

Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation

(2013) Hyun Jung Kim et al.   Integrative Biology

Patterning pluripotency in embryonic stem cells

(2013) Yue Shelby Zhang et al.   STEM CELLS

InVERT molding for scalable control of tissue microarchitecture

(2013) K. R. Stevens et al.   Nature Communications

Microbioreactors to manipulate oxygen tension and shear stress in the microenvironment of vascular stem and progenitor cells

(2012) Hasan E. Abaci et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Microfluidic bioreactor for dynamic regulation of early mesodermal commitment in human pluripotent stem cells

(2012) Elisa Cimetta et al.   LAB ON A CHIP

Micro-Arrayed Human Embryonic Stem Cells-Derived Cardiomyocytes for In Vitro Functional Assay

(2012) Elena Serena et al.   PLoS One

In vitro microvessels for the study of angiogenesis and thrombosis

(2012) Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

(2011) Steven J. Kattman et al.   Cell Stem Cell

Artificial niche microarrays for probing single stem cell fate in high throughput

(2011) Samy Gobaa et al.   NATURE METHODS

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Soft substrates drive optimal differentiation of human healthy and dystrophic myotubes

(2010) Elena Serena et al.   Integrative Biology

Microfluidic device generating stable concentration gradients for long term cell culture: application to Wnt3a regulation of β-catenin signaling

(2010) Elisa Cimetta et al.   LAB ON A CHIP

Differentiating Embryonic Stem Cells Pass through ‘Temporal Windows’ That Mark Responsiveness to Exogenous and Paracrine Mesendoderm Inducing Signals

(2010) Steven A. Jackson et al.   PLoS One

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

A Novel Miniaturized Multimodal Bioreactor for Continuous In Situ Assessment of Bioartificial Cardiac Tissue During Stimulation and Maturation

(2010) George Kensah et al.   TISSUE ENGINEERING PART C-METHODS

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development

(2008) Charles E. Murry et al.   CELL

Micro-bioreactor arrays for controlling cellular environments: Design principles for human embryonic stem cell applications

(2008) Elisa Cimetta et al.   METHODS

Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories

(2008) Céline Liu Bauwens et al.   STEM CELLS

Engineered Microenvironments for Controlled Stem Cell Differentiation

(2008) Jason A. Burdick et al.   TISSUE ENGINEERING PART A

Biomolecular gradients in cell culture systems

(2007) Thomas M. Keenan et al.   LAB ON A CHIP