Platelets in Systemic Sclerosis: the Missing Link Connecting Vasculopathy, Autoimmunity, and Fibrosis?

The role of platelets in the development and progression of pulmonary arterial hypertension

(2018) Remigiusz Kazimierczyk et al.   Advances in Medical Sciences

Systemic lupus erythematosus and systemic sclerosis: All roads lead to platelets

(2018) Marc Scherlinger et al.   AUTOIMMUNITY REVIEWS

Circulating Platelets as Mediators of Immunity, Inflammation, and Thrombosis

(2018) Milka Koupenova et al.   CIRCULATION RESEARCH

The significance of diminished sTWEAK and P-selectin content in platelets of patients with pulmonary arterial hypertension

(2018) Remigiusz Kazimierczyk et al.   CYTOKINE

Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma

(2018) Keith M. Sullivan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets

(2018) Stephanie Makhoul et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

From blood coagulation to innate and adaptive immunity: the role of platelets in the physiology and pathology of autoimmune disorders

(2018) Zuzanna Małgorzata Łukasik et al.   RHEUMATOLOGY INTERNATIONAL

Platelet and coagulation disorders in newly diagnosed patients with pulmonary arterial hypertension

(2018) Eleni Vrigkou et al.   PLATELETS

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

(2018) Norma Maugeri et al.   Science Translational Medicine

Hydroxychloroquine and joint involvement in systemic sclerosis: Preliminary beneficial results from a retrospective case-control series of an EUSTAR center

(2017) Cosimo Bruni et al.   JOINT BONE SPINE

A multicenter, open-label, comparative study of B-cell depletion therapy with Rituximab for systemic sclerosis-associated interstitial lung disease

(2017) Dimitrios Daoussis et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

The role of platelets in autoimmunity, vasculopathy, and fibrosis: Implications for systemic sclerosis

(2017) Konstantinos Ntelis et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Platelets as Modulators of Inflammation

(2017) Seok-Joo Kim et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

OP0034 The Serotonin Receptor 2 Inhibitor Terguride Has Beneficial Effects on Skin Fibrosis: Results from A Phase 2 Proof of Concept Study

(2016) O. Distler et al.   ANNALS OF THE RHEUMATIC DISEASES

Update of EULAR recommendations for the treatment of systemic sclerosis

(2016) Otylia Kowal-Bielecka et al.   ANNALS OF THE RHEUMATIC DISEASES

Platelet microparticles inhibit IL-17 production by regulatory T cells through P-selectin

(2016) S. Dinkla et al.   BLOOD

Clopidogrel treatment may associate with worsening of endothelial function and development of new digital ulcers in patients with systemic sclerosis: results from an open label, proof of concept study

(2016) Konstantinos Ntelis et al.   BMC MUSCULOSKELETAL DISORDERS

Platelets Induce Thymic Stromal Lymphopoietin Production by Endothelial Cells: Contribution to Fibrosis in Human Systemic Sclerosis

(2016) Marie-Elise Truchetet et al.   Arthritis & Rheumatology

Hydroxychloroquine as an anti-thrombotic in antiphospholipid syndrome

(2015) Cristina Belizna   AUTOIMMUNITY REVIEWS

The sGC stimulator riociguat inhibits platelet function in washed platelets but not in whole blood

(2015) C. Reiss et al.   BRITISH JOURNAL OF PHARMACOLOGY

Platelet Distribution Width and Mean Platelet Volume in Idiopathic Pulmonary Arterial Hypertension

(2015) Ya-Guo Zheng et al.   Heart Lung and Circulation

Platelets modulate the immune response following trauma by interaction with CD4+ T regulatory cells in a mouse model

(2015) Christian B. Bergmann et al.   IMMUNOLOGIC RESEARCH

Decreased Serotonin Levels and Serotonin-Mediated Osteoblastic Inhibitory Signaling in Patients With Ankylosing Spondylitis

(2015) Kalliopi Klavdianou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of angiogenesis by platelets in systemic sclerosis patients

(2015) Daniela Hirigoyen et al.   ARTHRITIS RESEARCH & THERAPY

Platelet activation and arterial peripheral serotonin turnover in cardiac remodeling associated to aortic stenosis

(2014) Charlotte Rouzaud-Laborde et al.   AMERICAN JOURNAL OF HEMATOLOGY

Emerging roles for platelets as immune and inflammatory cells

(2014) C. N. Morrell et al.   BLOOD

Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

(2014) Eileen M. Bauer et al.   CIRCULATION RESEARCH

Platelets in Rheumatic Diseases: Friend or Foe?

(2014) Armen Gasparyan et al.   CURRENT PHARMACEUTICAL DESIGN

Transforming growth factor β—at the centre of systemic sclerosis

(2014) Robert Lafyatis   Nature Reviews Rheumatology

Oxidative Stress Elicits Platelet/Leukocyte Inflammatory Interactions via HMGB1: A Candidate for Microvessel Injury in Sytemic Sclerosis

(2013) Norma Maugeri et al.   ANTIOXIDANTS & REDOX SIGNALING

Activated Platelets Enhance IL-10 Secretion and Reduce TNF-  Secretion by Monocytes

(2013) S. Gudbrandsdottir et al.   JOURNAL OF IMMUNOLOGY

Evidence for a Functional Thymic Stromal Lymphopoietin Signaling Axis in Fibrotic Lung Disease

(2013) A. Datta et al.   JOURNAL OF IMMUNOLOGY

Involvement of PDGF in Fibrosis and Scleroderma: Recent Insights from Animal Models and Potential Therapeutic Opportunities

(2013) Tomoaki Iwayama et al.   Current Rheumatology Reports

Platelet Level as a New Prognostic Factor for Idiopathic Pulmonary Arterial Hypertension in the Era of Combination Therapy

(2012) Hiroki Taguchi et al.   CIRCULATION JOURNAL

Increased mean platelet volume in primary Raynaud's phenomenon

(2011) Amir-Houshang Shemirani et al.   PLATELETS

Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors

(2011) Armen Yuri Gasparyan et al.   RHEUMATOLOGY INTERNATIONAL

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

(2010) D. Lievens et al.   BLOOD

Selective Serotonin Reuptake Inhibitors and the Incidence and Outcome of Pulmonary Hypertension

(2009) Sanjiv J. Shah et al.   CHEST

Transforming growth factor β as a therapeutic target in systemic sclerosis

(2009) John Varga et al.   Nature Reviews Rheumatology

Experience with rituximab in scleroderma: results from a 1-year, proof-of-principle study

(2009) Dimitrios Daoussis et al.   RHEUMATOLOGY

In Vitro Megakaryocyte Production and Platelet Biogenesis: State of the Art

(2009) Jo-Anna Reems et al.   TRANSFUSION MEDICINE REVIEWS

Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles

(2008) D. L. Sprague et al.   BLOOD

Clinical Significance of Serum HMGB-1 and sRAGE Levels in Systemic Sclerosis: Association with Disease Severity

(2008) Ayumi Yoshizaki et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of PDGF in fibrotic diseases and systemic sclerosis

(2008) M. Trojanowska   RHEUMATOLOGY