The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway

microRNA 223 Is Upregulated in the Multistep Progression of Barrett's Esophagus and Modulates Sensitivity to Chemotherapy by Targeting PARP1

(2013) M. M. Streppel et al.   CLINICAL CANCER RESEARCH

The TAL1 complex targets theFBXW7tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia

(2013) Marc R. Mansour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Catecholamine-Induced  2-Adrenergic Receptor Activation Mediates Desensitization of Gastric Cancer Cells to Trastuzumab by Upregulating MUC4 Expression

(2013) M. Shi et al.   JOURNAL OF IMMUNOLOGY

Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis

(2012) Y. Y. Janjigian et al.   ANNALS OF ONCOLOGY

MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4

(2012) Jinhai Li et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

microRNAs in cancer management

(2012) Yi W Kong et al.   LANCET ONCOLOGY

miR-23a Promotes the Transition from Indolent to Invasive Colorectal Cancer

(2012) Sohail Jahid et al.   Cancer Discovery

Clinicopathological and prognostic significance of HER-2/neu and VEGF expression in colon carcinomas

(2011) Qingguo Li et al.   BMC CANCER

Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in oesophageal squamous cell carcinoma

(2011) J Kurashige et al.   BRITISH JOURNAL OF CANCER

MicroRNA-125a-5p Is an Independent Prognostic Factor in Gastric Cancer and Inhibits the Proliferation of Human Gastric Cancer Cells in Combination with Trastuzumab

(2011) N. Nishida et al.   CLINICAL CANCER RESEARCH

Up-regulation ofmiR-21Mediates Resistance to Trastuzumab Therapy for Breast Cancer

(2011) Chang Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prognostic Implications of Altered Human Epidermal Growth Factor Receptors (HERs) in Gastric Carcinomas: HER2 and HER3 Are Predictors of Poor Outcome

(2011) Maria D. Begnami et al.   JOURNAL OF CLINICAL ONCOLOGY

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen

(2011) Q Wang et al.   ONCOGENE

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

(2010) Yung-Jue Bang et al.   LANCET

p53-Altered FBXW7 Expression Determines Poor Prognosis in Gastric Cancer Cases

(2009) T. Yokobori et al.   CANCER RESEARCH

MicroRNA-21 Regulates the Proliferation and Invasion in Esophageal Squamous Cell Carcinoma

(2009) Y. Hiyoshi et al.   CLINICAL CANCER RESEARCH

Survival prediction of gastric cancer by a seven-microRNA signature

(2009) X. Li et al.   GUT

The HER-2 Receptor and Breast Cancer: Ten Years of Targeted Anti-HER-2 Therapy and Personalized Medicine

(2009) J. S. Ross et al.   ONCOLOGIST

HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target

(2008) C. Gravalos et al.   ANNALS OF ONCOLOGY

S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial

(2008) Wasaburo Koizumi et al.   LANCET ONCOLOGY