A General Strategy for the Nickel-Catalyzed C−H Alkylation of Anilines

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition-Metal-Catalyzed C–N Bond Forming Reactions Using Organic Azides as the Nitrogen Source: A Journey for the Mild and Versatile C–H Amination

(2015) Kwangmin Shin et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Nickel(II)-Catalyzed Direct Benzylation, Allylation, Alkylation, and Methylation of C–H Bonds in Aromatic Amides Containing an 8-Aminoquinoline Moiety as the Directing Group

(2015) Yoshinori Aihara et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Nickel-catalyzed thiolation of unactivated aryl C–H bonds: efficient access to diverse aryl sulfides

(2015) Sheng-Yi Yan et al.   CHEMICAL COMMUNICATIONS

Ni(ii)-catalyzed dehydrative alkynylation of unactivated (hetero)aryl C–H bonds using oxygen: a user-friendly approach

(2015) Yan-Hua Liu et al.   CHEMICAL COMMUNICATIONS

Nickel-catalyzed direct thiolation of unactivated C(sp3)–H bonds with disulfides

(2015) Sheng-Yi Yan et al.   CHEMICAL COMMUNICATIONS

A sustainable and simple catalytic system for direct alkynylation of C(sp2)–H bonds with low nickel loadings

(2015) Yue-Jin Liu et al.   CHEMICAL COMMUNICATIONS

Ni(II)-Catalyzed Sulfonylation of ortho C–H Bonds in Aromatic Amides Utilizing an N,N-Bidentate Directing Group

(2015) Ayana Yokota et al.   CHEMISTRY LETTERS

Nickel Catalysts/N,N′-Bidentate Directing Groups: An Excellent Partnership in Directed C–H Activation Reactions

(2015) Luis C. Misal Castro et al.   CHEMISTRY LETTERS

Oxidation of Ni(II) to Ni(IV) with Aryl Electrophiles Enables Ni-Mediated Aryl–CF3 Coupling

(2015) James R. Bour et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed, Ring-Forming Aromatic C–H Alkylations with Unactivated Alkyl Halides

(2015) Alexander R. O. Venning et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Acyl Amino Acid Ligands for Ruthenium(II)-Catalyzed meta-C–H tert-Alkylation with Removable Auxiliaries

(2015) Jie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Aerobic Carbonylation of C(sp2)–H and C(sp3)–H Bonds through Ni/Cu Synergistic Catalysis with DMF as the Carbonyl Source

(2015) Xuesong Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Robust Ruthenium(II)-Catalyzed C–H Arylations: Carboxylate Assistance for the Efficient Synthesis of Angiotensin-II-Receptor Blockers

(2015) Lutz Ackermann   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Design, synthesis, and carbon-heteroatom coupling reactions of organometallic nickel(IV) complexes

(2015) N. M. Camasso et al.   SCIENCE

C–H arylation and alkenylation of imidazoles by nickel catalysis: solvent-accelerated imidazole C–H activation

(2015) Kei Muto et al.   Chemical Science

Cobalt-Catalyzed C–H Activation

(2015) Marc Moselage et al.   ACS Catalysis

Low-Valent Cobalt Catalysis: New Opportunities for C–H Functionalization

(2014) Ke Gao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Formal SN-Type Reactions in Rhodium(III)-Catalyzed CH Bond Activation

(2014) Nadine Kuhl et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Extended π-Systems through C-H Activation

(2014) Yasutomo Segawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A General Palladium-Catalyzed Method for Alkylation of Heteroarenes Using Secondary and Tertiary Alkyl Halides

(2014) Xiaojin Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed CH Alkylations: Direct Secondary Alkylations and Trifluoroethylations of Arenes

(2014) Weifeng Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Arene C–H functionalisation using a removable/modifiable or a traceless directing group strategy

(2014) Fengzhi Zhang et al.   CHEMICAL SOCIETY REVIEWS

Direct Arylation of C(sp3)–H Bonds in Aliphatic Amides with Diaryliodonium Salts in the Presence of a Nickel Catalyst

(2014) Miki Iyanaga et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel(II)-Catalyzed Direct Arylation of C–H Bonds in Aromatic Amides Containing an 8-Aminoquinoline Moiety as a Directing Group

(2014) Ayana Yokota et al.   JOURNAL OF ORGANIC CHEMISTRY

Cobalt-Catalyzed C–H Arylations, Benzylations, and Alkylations with Organic Electrophiles and Beyond

(2014) Lutz Ackermann   JOURNAL OF ORGANIC CHEMISTRY

Key Mechanistic Features of Ni-Catalyzed C–H/C–O Biaryl Coupling of Azoles and Naphthalen-2-yl Pivalates

(2014) Huiying Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd-Catalyzed Monoselective ortho-C–H Alkylation of N-Quinolyl Benzamides: Evidence for Stereoretentive Coupling of Secondary Alkyl Iodides

(2014) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Unified Strategy for Iron-Catalyzed ortho-Alkylation of Carboxamides

(2014) Erin R. Fruchey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Site-Selective Alkylation of Unactivated C(sp3)–H Bonds

(2014) Xuesong Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed Directed Alkylation of Aromatic and Olefinic Carboxamides with Primary and Secondary Alkyl Tosylates, Mesylates, and Halides

(2014) Laurean Ilies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Promoted Alkylation of C(sp3)–H and C(sp2)–H Bonds

(2014) Ru-Yi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni(II)-Catalyzed Oxidative Coupling between C(sp2)–H in Benzamides and C(sp3)–H in Toluene Derivatives

(2014) Yoshinori Aihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Anti-Cancer Pyrimidines in Diverse Scaffolds: A Review of Patent Literature

(2014) Ramandeep Kaur et al.   Recent Patents on Anti-Cancer Drug Discovery

Direct (Hetero)Arylation: A New Tool for Polymer Chemists

(2013) Lauren G. Mercier et al.   ACCOUNTS OF CHEMICAL RESEARCH

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations

(2013) Simon A. Girard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Alkenylation of Azoles with Enols and Esters by Nickel Catalysis

(2013) Lingkui Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-catalyzed alkyne annulation by anilines: versatile indole synthesis by C–H/N–H functionalization

(2013) Weifeng Song et al.   CHEMICAL COMMUNICATIONS

Cobalt-Catalyzed CH Bond Functionalizations with Aryl and Alkyl Chlorides

(2013) Benudhar Punji et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt-Catalyzed Ortho Alkylation of Aromatic Imines with Primary and Secondary Alkyl Halides

(2013) Ke Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed C–H Activation/Cross-Coupling of Pyridine N-Oxides with Nonactivated Secondary Alkyl Bromides

(2013) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

meta-Selective C–H Bond Alkylation with Secondary Alkyl Halides

(2013) Nora Hofmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides

(2013) Shu-Yu Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Direct Alkylation of C–H Bonds in Benzamides and Acrylamides with Functionalized Alkyl Halides via Bidentate-Chelation Assistance

(2013) Yoshinori Aihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Direct Arylation of C(sp3)–H Bonds in Aliphatic Amides via Bidentate-Chelation Assistance

(2013) Yoshinori Aihara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Nickel-Catalyzed Aromatic C–H Alkylation with Secondary or Tertiary Alkyl–Bromine Bonds for the Construction of Indolones

(2013) Chao Liu et al.   ORGANIC LETTERS

Programmed synthesis of arylthiazoles through sequential C–H couplings

(2013) Satoshi Tani et al.   Chemical Science

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Progress in Nickel-Catalyzed Biaryl Coupling

(2012) Junichiro Yamaguchi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Antituberculosis Drug Research: A Critical Overview

(2012) Beena et al.   MEDICINAL RESEARCH REVIEWS

Redox Non-Innocent Ligands: Versatile New Tools to Control Catalytic Reactions

(2012) Volodymyr Lyaskovskyy et al.   ACS Catalysis

User-Friendly [(Diglyme)NiBr2]-Catalyzed Direct Alkylations of Heteroarenes with Unactivated Alkyl Halides through CH Bond Cleavages

(2011) Lutz Ackermann et al.   ADVANCED SYNTHESIS & CATALYSIS

Nickel- and Cobalt-Catalyzed Direct Alkylation of Azoles with N-Tosylhydrazones Bearing Unactivated Alkyl Groups

(2011) Tomoyuki Yao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hydroarylation of alkynes catalyzed by nickel

(2011) Yoshiaki Nakao   CHEMICAL RECORD

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Direct Arylation as a Synthetic Tool for the Synthesis of Thiophene-Based Organic Electronic Materials

(2011) Derek J. Schipper et al.   CHEMISTRY OF MATERIALS

Nickel-Catalyzed C–H/C–O Coupling of Azoles with Phenol Derivatives

(2011) Kei Muto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Chelation-Assisted Transformations Involving Ortho C–H Bond Activation: Regioselective Oxidative Cycloaddition of Aromatic Amides to Alkynes

(2011) Hirotaka Shiota et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carboxylate-Assisted Ruthenium-Catalyzed Direct Alkylations of Ketimines

(2011) Lutz Ackermann et al.   ORGANIC LETTERS

Cobalt-Catalyzed, Chelation-Assisted C-H Bond Functionalization

(2011) Naohiko Yoshikai   SYNLETT

Nickel-catalyzed cross coupling of non-activated alkyl halides: a mechanistic perspective

(2011) Xile Hu   Chemical Science

The Nickel/Copper-Catalyzed Direct Alkylation of Heterocyclic CH Bonds

(2010) Oleg Vechorkin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Direct CH Arylation and Alkenylation of Heteroarenes with Organosilicon Reagents

(2010) Hitoshi Hachiya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalyzed direct alkylations of (hetero)arenes via C–H bond cleavages with unactivated alkyl halides

(2010) Lutz Ackermann   CHEMICAL COMMUNICATIONS

Palladium- and Nickel-Catalyzed Direct Alkylation of Azoles with Unactivated Alkyl Bromides and Chlorides

(2010) Tomoyuki Yao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Low-Valent Iron-Catalyzed C−C Bond Formation−Addition, Substitution, and C−H Bond Activation

(2010) Eiichi Nakamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Regioselective Direct Alkylation of Arenes with Unactivated Alkyl Halides through CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-CatalyzedorthoAlkylation of Benzoic Acids with Alkyl Halides

(2009) Yang-Hui Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition-Metal-Catalyzed Direct Arylation of (Hetero)Arenes by CH Bond Cleavage

(2009) Lutz Ackermann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS