Transmission phenotype of Mycobacterium tuberculosis strains is mechanistically linked to induction of distinct pulmonary pathology

Intensity of exposure to pulmonary tuberculosis determines risk of tuberculosis infection and disease

(2018) Carlos Acuña-Villaorduña et al.   EUROPEAN RESPIRATORY JOURNAL

Biology of clinical strains of Mycobacterium tuberculosis with varying levels of transmission

(2018) Crystal A. Shanley et al.   TUBERCULOSIS

Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense

(2018) Matthew Knight et al.   PLoS Pathogens

Strains of Mycobacterium tuberculosis transmitting infection in Brazilian households and those associated with community transmission of tuberculosis

(2017) Solange Alves Vinhas et al.   TUBERCULOSIS

The use of Masson's trichrome staining, second harmonic imaging and two-photon excited fluorescence of collagen in distinguishing intestinal tuberculosis from Crohn's disease

(2016) H. Mao et al.   Colorectal Disease

Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9

(2016) Alvaro A. Ordonez et al.   Disease Models & Mechanisms

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

(2016) Clare M. Smith et al.   mBio

Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis

(2016) Pierre Santucci et al.   Frontiers in Cellular and Infection Microbiology

Lipid droplet dynamics at early stages ofMycobacterium marinuminfection inDictyostelium

(2015) Caroline Barisch et al.   CELLULAR MICROBIOLOGY

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis

(2015) S. M. Irwin et al.   Disease Models & Mechanisms

Lung necrosis and neutrophils reflect common pathways of susceptibility to Mycobacterium tuberculosis in genetically diverse, immune-competent mice

(2015) Muhammad K. K. Niazi et al.   Disease Models & Mechanisms

Mouse models of human TB pathology: roles in the analysis of necrosis and the development of host-directed therapies

(2015) Igor Kramnik et al.   Seminars in Immunopathology

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Importance of Cough and M. tuberculosis Strain Type as Risks for Increased Transmission within Households

(2014) Edward C. Jones-López et al.   PLoS One

Consequences of genomic diversity in Mycobacterium tuberculosis

(2014) Mireia Coscolla et al.   SEMINARS IN IMMUNOLOGY

Pathogenicity of Mycobacterium tuberculosis Is Expressed by Regulating Metabolic Thresholds of the Host Macrophage

(2014) Parul Mehrotra et al.   PLoS Pathogens

Cough Aerosols ofMycobacterium tuberculosisPredict New Infection. A Household Contact Study

(2013) Edward C. Jones-López et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Long-term dominance of Mycobacterium tuberculosisUganda family in peri-urban Kampala-Uganda is not associated with cavitary disease

(2013) Eddie M Wampande et al.   BMC INFECTIOUS DISEASES

GPR109A and Vascular Inflammation

(2013) Joshua T. Chai et al.   Current Atherosclerosis Reports

Low Induction of Proinflammatory Cytokines Parallels Evolutionary Success of Modern Strains within the Mycobacterium tuberculosis Beijing Genotype

(2013) Arjan van Laarhoven et al.   INFECTION AND IMMUNITY

Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response

(2013) Jenny Carmona et al.   PLoS One

Clade-Specific Virulence Patterns of Mycobacterium tuberculosis Complex Strains in Human Primary Macrophages and Aerogenically Infected Mice

(2013) N. Reiling et al.   mBio

Variability of Infectious Aerosols Produced during Coughing by Patients with Pulmonary Tuberculosis

(2012) Kevin P. Fennelly et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Mycobacterium tuberculosis Beijing Strains Favor Transmission but Not Drug Resistance in China

(2012) C. Yang et al.   CLINICAL INFECTIOUS DISEASES

High-Resolution Genetic Mapping Using the Mouse Diversity Outbred Population

(2012) Karen L. Svenson et al.   GENETICS

The diversity outbred mouse population

(2012) Gary A. Churchill et al.   MAMMALIAN GENOME

Increased Transmission of Mycobacterium tuberculosis Beijing Genotype Strains Associated with Resistance to Streptomycin: A Population-Based Study

(2012) Tran N. Buu et al.   PLoS One

Modern Lineages of Mycobacterium tuberculosis Exhibit Lineage-Specific Patterns of Growth and Cytokine Induction in Human Monocyte-Derived Macrophages

(2012) Rajesh Sarkar et al.   PLoS One

Mouse Model of Necrotic Tuberculosis Granulomas Develops Hypoxic Lesions

(2011) Jamie Harper et al.   JOURNAL OF INFECTIOUS DISEASES

Reduced Transmissibility of East African Indian Strains of Mycobacterium tuberculosis

(2011) Amr S. Albanna et al.   PLoS One

Identification of factors for tuberculosis transmission via an integrated multidisciplinary approach

(2011) Sarah Talarico et al.   TUBERCULOSIS

Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis

(2011) Ashwin S. Dharmadhikari et al.   TUBERCULOSIS

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages

(2011) Damien Portevin et al.   PLoS Pathogens

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Mycobacterium tuberculosis strains with the Beijing genotype demonstrate variability in virulence associated with transmission

(2010) D. Aguilar L et al.   TUBERCULOSIS

Dominant Role of the sst1 Locus in Pathogenesis of Necrotizing Lung Granulomas during Chronic Tuberculosis Infection and Reactivation in Genetically Resistant Hosts

(2009) Alexander V. Pichugin et al.   AMERICAN JOURNAL OF PATHOLOGY

Mycobacterium tuberculosis Transmission Is Not Related to Household Genotype in a Setting of High Endemicity

(2009) B. J. Marais et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

High transmissibility of the modern Beijing Mycobacterium tuberculosis in homeless patients of Japan

(2009) Takayuki Wada et al.   TUBERCULOSIS

Recent and Rapid Emergence of W‐Beijing Strains ofMycobacterium tuberculosisin Cape Town, South Africa

(2008) Donna Cowley et al.   CLINICAL INFECTIOUS DISEASES

Progression to Active Tuberculosis, but Not Transmission, Varies byMycobacterium tuberculosisLineage in The Gambia

(2008) Bouke C. de Jong et al.   JOURNAL OF INFECTIOUS DISEASES

The clinical consequences of strain diversity in Mycobacterium tuberculosis

(2008) Mark P. Nicol et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens