Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

Impairing L-Threonine Catabolism Promotes Healthspan through Methylglyoxal-Mediated Proteohormesis

(2018) Meenakshi Ravichandran et al.   Cell Metabolism

A brief history of modern aging research

(2018) Kayvan Zainabadi   EXPERIMENTAL GERONTOLOGY

Identification of key pathways and metabolic fingerprints of longevity in C. elegans

(2018) Arwen W. Gao et al.   EXPERIMENTAL GERONTOLOGY

mixOmics: An R package for ‘omics feature selection and multiple data integration

(2017) Florian Rohart et al.   PLoS Computational Biology

A sensitive mass spectrometry platform identifies metabolic changes of life history traits in C. elegans

(2017) Arwen W. Gao et al.   Scientific Reports

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

(2016) Carsten Merkwirth et al.   CELL

The Expensive Germline and the Evolution of Ageing

(2016) Alexei A. Maklakov et al.   CURRENT BIOLOGY

A Caenorhabditis elegans Genome-Scale Metabolic Network Model

(2016) L. Safak Yilmaz et al.   Cell Systems

Growth hormone and aging: A challenging controversy

(2016) Andrzej Bartke   Clinical Interventions in Aging

One-carbon metabolism and epigenetics: understanding the specificity

(2015) Samantha J. Mentch et al.   Annals of the New York Academy of Sciences

Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans

(2015) Clare Edwards et al.   BMC GENETICS

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

(2015) Samantha J. Mentch et al.   Cell Metabolism

Metabolome and proteome changes with aging in Caenorhabditis elegans

(2015) Neil Copes et al.   EXPERIMENTAL GERONTOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Branched-chain amino acid catabolism is a conserved regulator of physiological ageing

(2015) Johannes Mansfeld et al.   Nature Communications

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

(2015) Osamu Hashizume et al.   Scientific Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Glycine treatment decreases proinflammatory cytokines and increases interferon-γ in patients with Type 2 diabetes

(2014) M. Cruz et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status

(2014) Byung Cheon Lee et al.   Nature Communications

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Glycine metabolism in animals and humans: implications for nutrition and health

(2013) Weiwei Wang et al.   AMINO ACIDS

Oral supplementation with glycine reduces oxidative stress in patients with metabolic syndrome, improving their systolic blood pressure

(2013) Margarita Díaz-Flores et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism

(2013) Filipe Cabreiro et al.   CELL

Glycine restores glutathione and protects against oxidative stress in vascular tissue from sucrose-fed rats

(2013) Angélica Ruiz-Ramírez et al.   CLINICAL SCIENCE

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation

(2012) A. T. van der Goot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Effect of glycine on the cyclooxygenase pathway of the kidney arachidonic acid metabolism in a rat model of metabolic syndrome

(2011) Israel Pérez-Torres et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans

(2011) Amy K. Walker et al.   CELL

Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway

(2011) Chunyu Jin et al.   Cell Metabolism

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

(2010) Laurent Mouchiroud et al.   AGING CELL

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

Metabolic Networks of Longevity

(2010) Riekelt H. Houtkooper et al.   CELL

Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans

(2010) Eric L. Greer et al.   NATURE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Glycine increases mRNA adiponectin and diminishes pro-inflammatory adipokines expression in 3T3-L1 cells

(2008) Rebeca Garcia-Macedo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY