Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain

Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion

(2018) Yubin Huang et al.   NATURE NEUROSCIENCE

Dual extra-retinal origins of microglia in the model of retinal microglia repopulation

(2018) Yubin Huang et al.   Cell Discovery

Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

(2017) Petra Füger et al.   NATURE NEUROSCIENCE

A new fate mapping system reveals context-dependent random or clonal expansion of microglia

(2017) Tuan Leng Tay et al.   NATURE NEUROSCIENCE

Microglial NFκB-TNFα hyperactivation induces obsessive–compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia

(2017) Grietje Krabbe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lifespan and Turnover of Microglia in the Human Brain

(2017) Pedro Réu et al.   Cell Reports

Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

(2017) Katharine Askew et al.   Cell Reports

Characterizing microglia activation: a spatial statistics approach to maximize information extraction

(2017) Benjamin M. Davis et al.   Scientific Reports

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

(2016) Adrian Olmos-Alonso et al.   BRAIN

Syndecans - key regulators of cell signaling and biological functions

(2016) Nikolaos A. Afratis et al.   FEBS Journal

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

Sall1 is a transcriptional regulator defining microglia identity and function

(2016) Anne Buttgereit et al.   NATURE IMMUNOLOGY

Origin, fate and dynamics of macrophages at central nervous system interfaces

(2016) Tobias Goldmann et al.   NATURE IMMUNOLOGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microglia development follows a stepwise program to regulate brain homeostasis

(2016) O. Matcovitch-Natan et al.   SCIENCE

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

(2015) Julia Bruttger et al.   IMMUNITY

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells

(2015) Jianpeng Sheng et al.   IMMUNITY

Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice

(2015) Nabil N. Dagher et al.   Journal of Neuroinflammation

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models

(2014) S Sakura Minami et al.   NATURE MEDICINE

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

RGS16 Restricts the Pro-Inflammatory Response of Monocytes

(2014) J. Suurväli et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Age-dependent fate and lineage restriction of single NG2 cells

(2011) X. Zhu et al.   DEVELOPMENT

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS