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Title
Optimal Synthetic Glycosylation of a Therapeutic Antibody
Authors
Keywords
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Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 55, Issue 7, Pages 2361-2367
Publisher
Wiley
Online
2016-01-12
DOI
10.1002/anie.201508723
References
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- (2013) Sara Rosati et al. mAbs
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- (2012) Robert M. Anthony et al. Annals of the New York Academy of Sciences
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- (2010) Antony J. Fairbanks COMPTES RENDUS CHIMIE
- Endo-β-N-acetylglucosaminidase-catalyzed polymerization of β-Glcp-(1→4)-GlcpNAc oxazoline: a revisit to enzymatic transglycosylation
- (2009) Hirofumi Ochiai et al. CARBOHYDRATE RESEARCH
- High-Dose Intravenous Immunoglobulin (IVIG) Therapy in Autoimmune Skin Blistering Diseases
- (2009) Norito Ishii et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Pharmacological significance of glycosylation in therapeutic proteins
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- (2009) Midori Umekawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2009) Roy Jefferis NATURE REVIEWS DRUG DISCOVERY
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- (2009) Royston Jefferis TRENDS IN PHARMACOLOGICAL SCIENCES
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- (2008) Christoph D. Heidecke et al. CHEMBIOCHEM
- Glycoprotein Synthesis: An Update
- (2008) David P. Gamblin et al. CHEMICAL REVIEWS
- Effect of constant and variable domain glycosylation on pharmacokinetics of therapeutic antibodies in mice
- (2007) Thomas A. Millward et al. BIOLOGICALS
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