Rapid and multi-level characterization of trastuzumab using sheathless capillary electrophoresis-tandem mass spectrometry

Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies

(2014) Hongwei Xie et al.   mAbs

Charge Heterogeneity of Monoclonal Antibodies by Multiplexed Imaged Capillary Isoelectric Focusing Immunoassay with Chemiluminescence Detection

(2012) David A. Michels et al.   ANALYTICAL CHEMISTRY

Biosimilar, Biobetter, and Next Generation Antibody Characterization by Mass Spectrometry

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Capillary electrophoresis-mass spectrometry methods for tryptic peptide mapping of therapeutic antibodies

(2012) Colin D. Whitmore et al.   ELECTROPHORESIS

Marketing approval of mogamulizumab

(2012) Alain Beck et al.   mAbs

Characterization of antibody variants during process development: The tale of incomplete processing of N-terminal secretion peptide

(2012) alexandre Ambrogelly et al.   mAbs

Marketed therapeutic antibodies compendium

(2012) Janice M. Reichert   mAbs

Characterization of drug-lysozyme conjugates by sheathless capillary electrophoresis–time-of-flight mass spectrometry

(2011) R. Haselberg et al.   ANALYTICA CHIMICA ACTA

Characterization of glycation in an IgG1 by capillary electrophoresis sodium dodecyl sulfate and mass spectrometry

(2011) Timothy Kaschak et al.   ANALYTICAL BIOCHEMISTRY

On-line characterization of monoclonal antibody variants by liquid chromatography–mass spectrometry operating in a two-dimensional format

(2011) Melissa Alvarez et al.   ANALYTICAL BIOCHEMISTRY

Optimization and Evaluation of a Sheathless Capillary Electrophoresis–Electrospray Ionization Mass Spectrometry Platform for Peptide Analysis: Comparison to Liquid Chromatography–Electrospray Ionization Mass Spectrometry

(2011) Klaus Faserl et al.   ANALYTICAL CHEMISTRY

Enhancing the Coverage of the Urinary Metabolome by Sheathless Capillary Electrophoresis-Mass Spectrometry

(2011) Rawi Ramautar et al.   ANALYTICAL CHEMISTRY

Use of CE-SDS gel for characterization of monoclonal antibody hinge region clipping due to copper and high pH stress

(2011) Richard R. Rustandi et al.   ELECTROPHORESIS

Worldwide experience with biosimilar development

(2011) Mark McCamish et al.   mAbs

High Capacity Capillary Electrophoresis-Electrospray Ionization Mass Spectrometry: Coupling a Porous Sheathless Interface with Transient-Isotachophoresis

(2010) Jean-Marc Busnel et al.   ANALYTICAL CHEMISTRY

Performance of a sheathless porous tip sprayer for capillary electrophoresis–electrospray ionization-mass spectrometry of intact proteins

(2010) Rob Haselberg et al.   JOURNAL OF CHROMATOGRAPHY A

New methods allowing the detection of protein aggregates

(2010) Barthélemy Demeule et al.   mAbs

European Medicines Agency workshop on biosimilar monoclonal antibodies

(2010) Janice M. Reichert et al.   mAbs

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding

(2010) Damian Houde et al.   MOLECULAR & CELLULAR PROTEOMICS

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody

(2009) Josef Vlasak et al.   ANALYTICAL BIOCHEMISTRY

GlycoFi's technology to control the glycosylation of recombinant therapeutic proteins

(2009) Alain Beck et al.   Expert Opinion on Drug Discovery

Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab

(2009) Carola W. N. Damen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

(2008) Alain Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The way forward, enhanced characterization of therapeutic antibody glycosylation: Comparison of three level mass spectrometry-based strategies

(2008) Elsa Wagner-Rousset et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mass spectrometry for structural characterization of therapeutic antibodies

(2008) Zhongqi Zhang et al.   MASS SPECTROMETRY REVIEWS

Heterogeneity of Monoclonal Antibodies

(2007) Hongcheng Liu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Glycosylation of Recombinant Antibody Therapeutics

(2005) Royston Jefferis   BIOTECHNOLOGY PROGRESS