Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase

FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination

(2018) Joiselle Blanche Fernandes et al.   PLoS Genetics

Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination

(2018) Carla M. Abreu et al.   Nature Communications

Two three-strand intermediates are processed during Rad51-driven DNA strand exchange

(2017) Kentaro Ito et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for the functional role of the Shu complex in homologous recombination

(2017) Shicheng Zhang et al.   NUCLEIC ACIDS RESEARCH

Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2

(2017) Rajula Elango et al.   Nature Communications

Two three-strand intermediates are processed during Rad51-driven DNA strand exchange

(2017) Kentaro Ito et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling

(2016) Martin R.G. Taylor et al.   MOLECULAR CELL

Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange

(2016) Jingfei Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange

(2016) Jingfei Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins

(2015) Rohit Prakash et al.   Cold Spring Harbor Perspectives in Biology

AAA-ATPase FIDGETIN-LIKE 1 and Helicase FANCM Antagonize Meiotic Crossovers by Distinct Mechanisms

(2015) Chloe Girard et al.   PLoS Genetics

Canonical Non-Homologous End Joining in Mitosis Induces Genome Instability and Is Suppressed by M-phase-Specific Phosphorylation of XRCC4

(2014) Masahiro Terasawa et al.   PLoS Genetics

FBH1 Helicase Disrupts RAD51 Filamentsin Vitroand Modulates Homologous Recombination in Mammalian Cells

(2013) Jitka Simandlova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAD51C-Deficient Cancer Cells Are Highly Sensitive to the PARP Inhibitor Olaparib

(2013) A. Min et al.   MOLECULAR CANCER THERAPEUTICS

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

(2013) Carrie A. Adelman et al.   NATURE

Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair

(2013) L. Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FIGNL1-containing protein complex is required for efficient homologous recombination repair

(2013) J. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new protein complex promoting the assembly of Rad51 filaments

(2013) Hiroyuki Sasanuma et al.   Nature Communications

Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

(2012) J. Chun et al.   MOLECULAR AND CELLULAR BIOLOGY

hSWS1·SWSAP1 Is an Evolutionarily Conserved Complex Required for Efficient Homologous Recombination Repair

(2011) Ting Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Homologous Recombination by the PCNA-Interacting Protein PARI

(2011) George-Lucian Moldovan et al.   MOLECULAR CELL

Rad51 paralogues Rad55–Rad57 balance the antirecombinase Srs2 in Rad51 filament formation

(2011) Jie Liu et al.   NATURE

Fidgetin-Like1 Is a Strong Candidate for a Dynamic Impairment of Male Meiosis Leading to Reduced Testis Weight in Mice

(2011) David L'Hôte et al.   PLoS One

Rad51C is essential for embryonic development and haploinsufficiency causes increased DNA damage sensitivity and genomic instability

(2010) Godelieve Smeenk et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Loss of Rad51c Leads to Embryonic Lethality and Modulation of Trp53-Dependent Tumorigenesis in Mice

(2009) S. G. Kuznetsov et al.   CANCER RESEARCH

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

(2009) Eeson Rajendra et al.   NUCLEIC ACIDS RESEARCH

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

(2008) J Ross Chapman et al.   EMBO REPORTS