Alternative Splicing in Apicomplexan Parasites

Comparative studies of Toxoplasma gondii transcriptomes: insights into stage conversion based on gene expression profiling and alternative splicing

(2018) Long-Fei Chen et al.   Parasites & Vectors

The N-terminal RNA Recognition Motif of PfSR1 Confers Semi-specificity for Pyrimidines during RNA Recognition

(2018) Akshay Kumar Ganguly et al.   JOURNAL OF MOLECULAR BIOLOGY

Capturing in vivo RNA transcriptional dynamics from the malaria parasite Plasmodium falciparum

(2017) Heather J. Painter et al.   GENOME RESEARCH

Detection of Proteome Diversity Resulted from Alternative Splicing is Limited by Trypsin Cleavage Specificity

(2017) Xiaojing Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

The Relationship between Alternative Splicing and Proteomic Complexity

(2017) Benjamin J. Blencowe   TRENDS IN BIOCHEMICAL SCIENCES

Most Alternative Isoforms Are Not Functionally Important

(2017) Michael L. Tress et al.   TRENDS IN BIOCHEMICAL SCIENCES

Alternative Splicing May Not Be the Key to Proteome Complexity

(2017) Michael L. Tress et al.   TRENDS IN BIOCHEMICAL SCIENCES

Eteplirsen in the treatment of Duchenne muscular dystrophy

(2017) Kenji Rowel Lim et al.   Drug Design Development and Therapy

Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy

(2017) Yukiya Sako et al.   Scientific Reports

Impact of Alternative Splicing on the Human Proteome

(2017) Yansheng Liu et al.   Cell Reports

UTR introns, antisense RNA and differentially spliced transcripts between Plasmodium yoelii subspecies

(2016) Jian Li et al.   MALARIA JOURNAL

Pharmacology of Modulators of Alternative Splicing

(2016) David O. Bates et al.   PHARMACOLOGICAL REVIEWS

Alternative Splicing of G9a Regulates Neuronal Differentiation

(2016) Ana Fiszbein et al.   Cell Reports

New insights into the Plasmodium vivax transcriptome using RNA-Seq

(2016) Lei Zhu et al.   Scientific Reports

Modulation of Alternative Splicing with Chemical Compounds in New Therapeutics for Human Diseases

(2015) Kenji Ohe et al.   ACS Chemical Biology

Most Highly Expressed Protein-Coding Genes Have a Single Dominant Isoform

(2015) Iakes Ezkurdia et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of Splicing Factors by Alternative Splicing and NMD Is Conserved between Kingdoms Yet Evolutionarily Flexible

(2015) Liana F. Lareau et al.   MOLECULAR BIOLOGY AND EVOLUTION

PfSR1 controls alternative splicing and steady-state RNA levels inPlasmodium falciparumthrough preferential recognition of specific RNA motifs

(2015) Shiri Eshar et al.   MOLECULAR MICROBIOLOGY

A serine–arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii

(2015) Lee M. Yeoh et al.   NUCLEIC ACIDS RESEARCH

Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates inPlasmodium falciparum

(2015) Aprajita Garg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems-Based Analysis of the Sarcocystis neurona Genome Identifies Pathways That Contribute to a Heteroxenous Life Cycle

(2015) Tomasz Blazejewski et al.   mBio

Alternatively Spliced Homologous Exons Have Ancient Origins and Are Highly Expressed at the Protein Level

(2015) Federico Abascal et al.   PLoS Computational Biology

A dual-targeted aminoacyl-tRNA synthetase inPlasmodium falciparumcharges cytosolic and apicoplast tRNACys

(2014) James S. Pham et al.   BIOCHEMICAL JOURNAL

The Babesia bovis gene and promoter model: an update from full-length EST analysis

(2014) Junya Yamagishi et al.   BMC GENOMICS

Human CDC2-Like Kinase 1 (CLK1): A Novel Target for Alzheimer’s Disease

(2014) Princi Jain et al.   CURRENT DRUG TARGETS

Transcript maturation in apicomplexan parasites

(2014) Elena S Suvorova et al.   CURRENT OPINION IN MICROBIOLOGY

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients

(2014) N. B. Gadalla et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Sequencing depth and coverage: key considerations in genomic analyses

(2014) David Sims et al.   NATURE REVIEWS GENETICS

Inhibition of the SR Protein-Phosphorylating CLK Kinases of Plasmodium falciparum Impairs Blood Stage Replication and Malaria Transmission

(2014) Selina Kern et al.   PLoS One

Organization of Plasmodium falciparum spliceosomal core complex and role of arginine methylation in its assembly

(2013) Manzar Hossain et al.   MALARIA JOURNAL

Evaluating the Impact of Sequencing Depth on Transcriptome Profiling in Human Adipose

(2013) Yichuan Liu et al.   PLoS One

Discovery of a Splicing Regulator Required for Cell Cycle Progression

(2013) Elena S. Suvorova et al.   PLoS Genetics

Polysome profiling reveals translational control of gene expression in the human malaria parasite Plasmodium falciparum

(2013) Evelien M Bunnik et al.   GENOME BIOLOGY

De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs

(2012) Musa A Hassan et al.   BMC GENOMICS

Detecting differential usage of exons from RNA-seq data

(2012) S. Anders et al.   GENOME RESEARCH

Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti†

(2012) Emmanuel Cornillot et al.   NUCLEIC ACIDS RESEARCH

A novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites’ proliferation in human erythrocytes

(2012) Shiri Eshar et al.   NUCLEIC ACIDS RESEARCH

The significant other: splicing by the minor spliceosome

(2012) Janne J. Turunen et al.   Wiley Interdisciplinary Reviews-RNA

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

(2011) María J López-Barragán et al.   BMC GENOMICS

Two nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factor

(2011) Shruti Agarwal et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Quantitative Time-course Profiling of Parasite and Host Cell Proteins in the Human Malaria ParasitePlasmodium falciparum

(2011) Bernardo Javier Foth et al.   MOLECULAR & CELLULAR PROTEOMICS

RNA-Seq analysis of splicing in Plasmodium falciparum uncovers new splice junctions, alternative splicing and splicing of antisense transcripts

(2011) K. Sorber et al.   NUCLEIC ACIDS RESEARCH

Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

(2011) Lev Solyakov et al.   Nature Communications

Transition of Plasmodium Sporozoites into Liver Stage-Like Forms Is Regulated by the RNA Binding Protein Pumilio

(2011) Carina S. S. Gomes-Santos et al.   PLoS Pathogens

Plasmodium falciparum spliceosomal RNAs: 3′ and 5′ end processing

(2010) Calvo Eliana et al.   ACTA TROPICA

The Systematic Functional Analysis of Plasmodium Protein Kinases Identifies Essential Regulators of Mosquito Transmission

(2010) Rita Tewari et al.   Cell Host & Microbe

PfSRPK1, a Novel Splicing-related Kinase fromPlasmodium falciparum

(2010) Aparna Dixit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum

(2010) J. Miao et al.   JOURNAL OF CELL SCIENCE

New insights into the blood-stage transcriptome ofPlasmodium falciparumusing RNA-Seq

(2010) Thomas D. Otto et al.   MOLECULAR MICROBIOLOGY

Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNAMet formylation in Apicomplexa

(2010) Paco Pino et al.   MOLECULAR MICROBIOLOGY

Universal Features of Post-Transcriptional Gene Regulation Are Critical for Plasmodium Zygote Development

(2010) Gunnar R. Mair et al.   PLoS Pathogens

Characterization of PRMT1 fromPlasmodium falciparum

(2009) Qi Fan et al.   BIOCHEMICAL JOURNAL

5′ and 3′ end modifications of spliceosomal RNAs in Plasmodium falciparum

(2009) Praveen Bawankar et al.   MOLECULAR BIOLOGY REPORTS

A small-scale systematic analysis of alternative splicing in Plasmodium falciparum

(2009) Hideyuki Iriko et al.   PARASITOLOGY INTERNATIONAL

The SR protein family

(2009) Peter J Shepard et al.   GENOME BIOLOGY

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Full-Malaria/Parasites and Full-Arthropods: databases of full-length cDNAs of parasites and arthropods, update 2009

(2008) H. Wakaguri et al.   NUCLEIC ACIDS RESEARCH

Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

(2008) Bernardo J Foth et al.   GENOME BIOLOGY