Dopamine Is a Siderophore-Like Iron Chelator That Promotes Salmonella enterica Serovar Typhimurium Virulence in Mice

Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages

(2018) Stefanie Dichtl et al.   BIOCHEMICAL PHARMACOLOGY

Role of divalent metals in infectious disease susceptibility and outcome

(2018) G. Weiss et al.   CLINICAL MICROBIOLOGY AND INFECTION

Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection

(2017) Manfred Nairz et al.   Frontiers in Cellular and Infection Microbiology

Heme oxygenase 1 controls early innate immune response of macrophages toSalmonellaTyphimurium infection

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Siderophore-based immunization strategy to inhibit growth of enteric pathogens

(2016) Martina Sassone-Corsi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC

(2016) Zhi Li et al.   Scientific Reports

Pharmacological Targeting of the Hepcidin/Ferroportin Axis

(2016) Giada Sebastiani et al.   Frontiers in Pharmacology

The Iron age of host-microbe interactions

(2015) M. P. Soares et al.   EMBO REPORTS

Lipocalin-2 ensures host defense againstSalmonellaTyphimurium by controlling macrophage iron homeostasis and immune response

(2015) Manfred Nairz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Now you see me, now you don't: the interaction of Salmonella with innate immune receptors

(2015) A. Marijke Keestra-Gounder et al.   NATURE REVIEWS MICROBIOLOGY

Salmonellae interactions with host processes

(2015) Doris L. LaRock et al.   NATURE REVIEWS MICROBIOLOGY

Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection

(2014) Zhuoming Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis

(2014) Don-Kyu Kim et al.   NATURE MEDICINE

QseC Inhibitors as an Antivirulence Approach for Gram-Negative Pathogens

(2014) Meredith M. Curtis et al.   mBio

Norepinephrine and dopamine increase motility, biofilm formation, and virulence of Vibrio harveyi

(2014) Qian Yang et al.   Frontiers in Microbiology

Iron at the interface of immunity and infection

(2014) Manfred Nairz et al.   Frontiers in Pharmacology

Iron in Infection and Immunity

(2013) James E. Cassat et al.   Cell Host & Microbe

Nitric oxide–mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection

(2013) Manfred Nairz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interplay between the QseC and QseE Bacterial Adrenergic Sensor Kinases in Salmonella enterica Serovar Typhimurium Pathogenesis

(2012) Cristiano G. Moreira et al.   INFECTION AND IMMUNITY

Hepcidin and the Iron-Infection Axis

(2012) H. Drakesmith et al.   SCIENCE

Metallobiology of host–pathogen interactions: an intoxicating new insight

(2012) Hélène Botella et al.   TRENDS IN MICROBIOLOGY

Staphylococcus aureus Transporters Hts, Sir, and Sst Capture Iron Liberated from Human Transferrin by Staphyloferrin A, Staphyloferrin B, and Catecholamine Stress Hormones, Respectively, and Contribute to Virulence

(2011) Federico C. Beasley et al.   INFECTION AND IMMUNITY

A central metabolic circuit controlled by QseC in pathogenic Escherichia coli

(2011) Maria Hadjifrangiskou et al.   MOLECULAR MICROBIOLOGY

Neutrophil Gelatinase-Associated Lipocalin Expresses Antimicrobial Activity by Interfering with L-Norepinephrine-Mediated Bacterial Iron Acquisition

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Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

The phage shock protein PspA facilitates divalent metal transport and is required for virulence of Salmonella enterica sv. Typhimurium

(2010) Joyce E. Karlinsey et al.   MOLECULAR MICROBIOLOGY

Comparison of Dopamine and Norepinephrine in the Treatment of Shock

(2010) Daniel De Backer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Absence of functional Hfe protects mice from invasive Salmonella enterica Serovar Typhimurium infection via induction of lipocalin-2

(2009) M. Nairz et al.   BLOOD

QseC Mediates Salmonella enterica Serovar Typhimurium Virulence In Vitro and In Vivo

(2009) C. G. Moreira et al.   INFECTION AND IMMUNITY

Elucidation of the Mechanism by Which Catecholamine Stress Hormones Liberate Iron from the Innate Immune Defense Proteins Transferrin and Lactoferrin

(2009) S. M. Sandrini et al.   JOURNAL OF BACTERIOLOGY

The QseC Adrenergic Signaling Cascade in Enterohemorrhagic E. coli (EHEC)

(2009) David T. Hughes et al.   PLoS Pathogens

Iron depletion limits intracellular bacterial growth in macrophages

(2008) P. N. Paradkar et al.   BLOOD

Iron regulated genes of Salmonella enterica serovar Typhimurium in response to norepinephrine and the requirement of fepDGC for norepinephrine-enhanced growth

(2008) Bradley L. Bearson et al.   MICROBES AND INFECTION

Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium

(2008) Marie-Laure V. Crouch et al.   MOLECULAR MICROBIOLOGY