Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inflammation, necrosis, and the kinase RIP3 are key mediators of AAG-dependent alkylation-induced retinal degeneration
Authors
Keywords
-
Journal
Science Signaling
Volume 12, Issue 568, Pages eaau9216
Publisher
American Association for the Advancement of Science (AAAS)
Online
2019-02-13
DOI
10.1126/scisignal.aau9216
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AIF-independent parthanatos in the pathogenesis of dry age-related macular degeneration
- (2017) Ki-Hong Jang et al. Cell Death & Disease
- ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage
- (2017) Jennifer J Jordan et al. Cell Death & Disease
- PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration
- (2017) Mariacarmela Allocca et al. Oncotarget
- Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms
- (2017) Carrie M. Margulies et al. PLoS One
- Necroptosis and Inflammation
- (2016) Kim Newton et al. Annual Review of Biochemistry
- RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
- (2016) K Newton et al. CELL DEATH AND DIFFERENTIATION
- Necroptosis-independent signaling by the RIP kinases in inflammation
- (2016) Kenta Moriwaki et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4
- (2016) Malek Najjar et al. IMMUNITY
- Regulated necrosis: disease relevance and therapeutic opportunities
- (2016) Marcus Conrad et al. NATURE REVIEWS DRUG DISCOVERY
- Parp1 protects against Aag-dependent alkylation-induced nephrotoxicity in a sex-dependent manner
- (2016) Jennifer A. Calvo et al. Oncotarget
- Extracellular Poly(ADP-Ribose) Is a Pro-inflammatory Signal for Macrophages
- (2015) Kristin A. Krukenberg et al. CHEMISTRY & BIOLOGY
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
- (2015) Kate E. Lawlor et al. Nature Communications
- N -methyl- N -nitrosourea-induced retinal degeneration in mice
- (2014) Yuan-yuan Chen et al. EXPERIMENTAL EYE RESEARCH
- Cell Death-Associated Molecular-Pattern Molecules: Inflammatory Signaling and Control
- (2014) Beatriz Sangiuliano et al. MEDIATORS OF INFLAMMATION
- Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
- (2014) Huayi Wang et al. MOLECULAR CELL
- Regulated necrosis: the expanding network of non-apoptotic cell death pathways
- (2014) Tom Vanden Berghe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Necroptosis
- (2014) Andreas Linkermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Molecular mechanisms of regulated necrosis
- (2014) Lorenzo Galluzzi et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- ARTD1/PARP1 Negatively Regulates Glycolysis by Inhibiting Hexokinase 1 Independent of NAD + Depletion
- (2014) Elise Fouquerel et al. Cell Reports
- Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration
- (2013) Y Murakami et al. CELL DEATH AND DIFFERENTIATION
- TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
- (2013) Justyna Sosna et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
- (2013) James M. Murphy et al. IMMUNITY
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Differential regulation of cell death programs in males and females by Poly (ADP-Ribose) Polymerase-1 and 17 β estradiol
- (2013) N R Jog et al. Cell Death & Disease
- Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1
- (2013) Jennifer A. Calvo et al. PLoS Genetics
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
- (2012) Liming Sun et al. CELL
- Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes
- (2012) Péter Bai et al. FEBS LETTERS
- Damage of DNA and proteins by major lipid peroxidation products in genome stability
- (2012) Alicja Winczura et al. FREE RADICAL RESEARCH
- On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
- (2012) X. Luo et al. GENES & DEVELOPMENT
- Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation
- (2012) James E. Vince et al. IMMUNITY
- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
- (2012) Tae-Bong Kang et al. IMMUNITY
- Receptor interacting protein kinase mediates necrotic cone but not rod cell death in a mouse model of inherited degeneration
- (2012) Y. Murakami et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
- (2012) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation
- (2012) M Baritaud et al. Cell Death & Disease
- Signaling Mechanism of Poly(ADP-Ribose) Polymerase-1 (PARP-1) in Inflammatory Diseases
- (2011) Xueqing Ba et al. AMERICAN JOURNAL OF PATHOLOGY
- Functional complementation between FADD and RIP1 in embryos and lymphocytes
- (2011) Haibing Zhang et al. NATURE
- PARG is recruited to DNA damage sites through poly(ADP-ribose)- and PCNA-dependent mechanisms
- (2011) Oliver Mortusewicz et al. NUCLEIC ACIDS RESEARCH
- Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)
- (2011) Y. Wang et al. Science Signaling
- Sex Differences in the Response to Poly(ADP-ribose) Polymerase-1 Deletion and Caspase Inhibition After Stroke
- (2011) Fudong Liu et al. STROKE
- HMGB1 and RAGE in Inflammation and Cancer
- (2010) Gary P. Sims et al. Annual Review of Immunology
- The role of PARP activation in glutamate-induced necroptosis in HT-22 cells
- (2010) Xingshun Xu et al. BRAIN RESEARCH
- AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX
- (2010) Cédric Artus et al. EMBO JOURNAL
- NAD+ Depletion Is Necessary and Sufficient forPoly(ADP-Ribose) Polymerase-1-Mediated Neuronal Death
- (2010) C. C. Alano et al. JOURNAL OF NEUROSCIENCE
- Molecular mechanisms of necroptosis: an ordered cellular explosion
- (2010) Peter Vandenabeele et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
- (2010) G. Trichonas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of the Kinases RIP1 and RIP3 in TNF-Induced Necrosis
- (2010) P. Vandenabeele et al. Science Signaling
- Recognition and Processing of a New Repertoire of DNA Substrates by Human 3-Methyladenine DNA Glycosylase (AAG)†
- (2009) Chun-Yue I. Lee et al. BIOCHEMISTRY
- Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- (2009) YoungSik Cho et al. CELL
- Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
- (2009) Sudan He et al. CELL
- DNA Repair in Mammalian Cells
- (2009) A. B. Robertson et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke
- (2009) Mike Yuan et al. EXPERIMENTAL NEUROLOGY
- Poly(ADP-Ribose) Polymerase-1 Regulates the Progression of Autoimmune Nephritis in Males by Inducing Necrotic Cell Death and Modulating Inflammation
- (2009) N. R. Jog et al. JOURNAL OF IMMUNOLOGY
- A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
- (2009) Gyula Timinszky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice
- (2009) Lisiane B. Meira et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler
- (2009) A. J. Gottschalk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
- (2009) D. Ahel et al. SCIENCE
- RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
- (2009) D.-W. Zhang et al. SCIENCE
- Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks
- (2008) Bethany C. Woodhouse et al. DNA REPAIR
- Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs
- (2008) Sugako Oka et al. EMBO JOURNAL
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
- Single-strand break repair and genetic disease
- (2008) Keith W. Caldecott NATURE REVIEWS GENETICS
- Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes
- (2008) R. Krishnakumar et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started