Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1

Inhibition of poly(ADP-ribose) polymerase inhibits ischemia/reperfusion induced neurodegeneration in retina via suppression of endoplasmic reticulum stress

(2012) Chuanzhou Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

(2012) J. Murai et al.   CANCER RESEARCH

N-Methylpurine DNA Glycosylase and OGG1 DNA Repair Activities: Opposite Associations With Lung Cancer Risk

(2012) Yael Leitner-Dagan et al.   JNCI-Journal of the National Cancer Institute

Increased PARP-1 Association with DNA in Alkylation Damaged, PARP-Inhibited Mouse Fibroblasts

(2012) P. S. Kedar et al.   MOLECULAR CANCER RESEARCH

Elevated N3-methylpurine-DNA glycosylase DNA repair activity is associated with lung cancer

(2012) Philip A.J. Crosbie et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus

(2012) W. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates

(2012) A. G. Senejani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct repair of 3,N4-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase

(2011) Dragony Fu et al.   DNA REPAIR

A subset of chronic lymphocytic leukemia patients display reduced levels of PARP1 expression coupled with a defective irradiation-induced apoptosis

(2011) Maria Giulia Bacalini et al.   EXPERIMENTAL HEMATOLOGY

Alkylpurine–DNA–N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients

(2011) Sameer Agnihotri et al.   JOURNAL OF CLINICAL INVESTIGATION

N-methylpurine DNA glycosylase and DNA polymerase β modulate BER inhibitor potentiation of glioma cells to temozolomide

(2011) Jiang-bo Tang et al.   NEURO-ONCOLOGY

Mitochondrial and Nuclear Cross Talk in Cell Death

(2010) Shaida A. Andrabi et al.   Annals of the New York Academy of Sciences

Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers

(2010) A Al-Attar et al.   BRITISH JOURNAL OF CANCER

Targeting poly(ADP-ribose) polymerase activity for cancer therapy

(2010) Frédérique Mégnin-Chanet et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small molecule inhibitors of DNA repair nuclease activities of APE1

(2010) David M. Wilson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bioenergetic Metabolites Regulate Base Excision Repair-Dependent Cell Death in Response to DNA Damage

(2010) J.-b. Tang et al.   MOLECULAR CANCER RESEARCH

Parp1 activation in mouse embryonic fibroblasts promotes Pol β-dependent cellular hypersensitivity to alkylation damage

(2010) Elena Jelezcova et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mismatch repair deficient colorectal cancer in the era of personalized treatment

(2010) Madeleine Hewish et al.   Nature Reviews Clinical Oncology

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

(2010) C. E. Strom et al.   NUCLEIC ACIDS RESEARCH

PARP1 Gene Knock-Out Increases Resistance to Retinal Degeneration without Affecting Retinal Function

(2010) Ayse Sahaboglu et al.   PLoS One

Toward a unified nomenclature for mammalian ADP-ribosyltransferases

(2010) Michael O. Hottiger et al.   TRENDS IN BIOCHEMICAL SCIENCES

AIF: Not Just an Apoptosis-Inducing Factor

(2009) Nicholas Joza et al.   Annals of the New York Academy of Sciences

Recognition and Processing of a New Repertoire of DNA Substrates by Human 3-Methyladenine DNA Glycosylase (AAG)†

(2009) Chun-Yue I. Lee et al.   BIOCHEMISTRY

Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines

(2009) T Zaremba et al.   BRITISH JOURNAL OF CANCER

DNA Repair in Mammalian Cells

(2009) A. B. Robertson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DNA repair modulates the vulnerability of the developing brain to alkylating agents

(2009) G.E. Kisby et al.   DNA REPAIR

DNA repair deficiency and neurological disease

(2009) Peter J. McKinnon   NATURE REVIEWS NEUROSCIENCE

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

(2009) Gyula Timinszky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA Damage, Aging, and Cancer

(2009) Jan H.J. Hoeijmakers   NEW ENGLAND JOURNAL OF MEDICINE

Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice

(2009) Lisiane B. Meira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

(2009) A. J. Gottschalk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1

(2009) D. Ahel et al.   SCIENCE

DNA strand breaks, neurodegeneration and aging in the brain

(2008) Sachin Katyal et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Human Methyl Purine DNA Glycosylase and DNA Polymerase   Expression Collectively Predict Sensitivity to Temozolomide

(2008) R. N. Trivedi et al.   MOLECULAR PHARMACOLOGY

Mutational specificity and genetic control of replicative bypass of an abasic site in yeast

(2008) V. Pages et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes

(2008) R. Krishnakumar et al.   SCIENCE