Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8

Mechanism of NMDA receptor channel block by MK-801 and memantine

(2018) Xianqiang Song et al.   NATURE

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability

(2017) Benjamin Davies et al.   HUMAN MOLECULAR GENETICS

Engineering defined membrane-embedded elements of AMPA receptor induces opposing gating modulation by cornichon 3 and stargazin

(2017) Natalie M. Hawken et al.   JOURNAL OF PHYSIOLOGY-LONDON

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning

(2017) Zikai Zhou et al.   NATURE NEUROSCIENCE

Structural and Functional Architecture of AMPA-Type Glutamate Receptors and Their Auxiliary Proteins

(2017) Ingo H. Greger et al.   NEURON

Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes

(2017) Edward C. Twomey et al.   NEURON

Subunit-specific role for the amino-terminal domain of AMPA receptors in synaptic targeting

(2017) Javier Díaz-Alonso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual Effects of TARP γ-2 on Glutamate Efficacy Can Account for AMPA Receptor Autoinactivation

(2017) Ian D. Coombs et al.   Cell Reports

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains

(2017) Huaying Zhao et al.   eLife

Control of AMPA receptor activity by the extracellular loops of auxiliary proteins

(2017) Irene Riva et al.   eLife

Synaptic transmission and plasticity require AMPA receptor anchoring via its N-terminal domain

(2017) Jake F Watson et al.   eLife

Recent developments in the CCP-EM software suite

(2017) Tom Burnley et al.   Acta Crystallographica Section D-Structural Biology

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM

(2016) Yan Zhao et al.   NATURE

Structural basis of kainate subtype glutamate receptor desensitization

(2016) Joel R. Meyerson et al.   NATURE

Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism

(2016) Akihiko S Kato et al.   NATURE MEDICINE

Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes

(2016) G. Brent Dawe et al.   NEURON

GluA1 signal peptide determines the spatial assembly of heteromeric AMPA receptors

(2016) Xue-Yan He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and organization of heteromeric AMPA-type glutamate receptors

(2016) Beatriz Herguedas et al.   SCIENCE

Structural basis for integration of GluD receptors within synaptic organizer complexes

(2016) Jonathan Elegheert et al.   SCIENCE

Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy

(2016) E. C. Twomey et al.   SCIENCE

IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly

(2016) Javier García-Nafría et al.   Scientific Reports

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States

(2014) Katharina L. Dürr et al.   CELL

NMDA receptor structures reveal subunit arrangement and pore architecture

(2014) Chia-Hsueh Lee et al.   NATURE

Mechanical coupling maintains the fidelity of NMDA receptor–mediated currents

(2014) Rashek Kazi et al.   NATURE NEUROSCIENCE

Regional Diversity and Developmental Dynamics of the AMPA-Receptor Proteome in the Mammalian Brain

(2014) Jochen Schwenk et al.   NEURON

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism

(2014) L. Chen et al.   SCIENCE

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

Crystal structure of a heterotetrameric NMDA receptor ion channel

(2014) E. Karakas et al.   SCIENCE

TRPV1 structures in distinct conformations reveal activation mechanisms

(2013) Erhu Cao et al.   NATURE

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting

(2013) P. Hastie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-resolution refinement tools inREFMAC5

(2012) Robert A. Nicholls et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

LTP requires a reserve pool of glutamate receptors independent of subunit type

(2012) Adam J. Granger et al.   NATURE

High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes

(2012) Jochen Schwenk et al.   NEURON

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers

(2011) Maxim Rossmann et al.   EMBO JOURNAL

Dynamics and allosteric potential of the AMPA receptor N-terminal domain

(2011) Madhav Sukumaran et al.   EMBO JOURNAL

The crystal structure of a voltage-gated sodium channel

(2011) Jian Payandeh et al.   NATURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hippocampal AMPA Receptor Gating Controlled by Both TARP and Cornichon Proteins

(2010) Akihiko S. Kato et al.   NEURON

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Structural and thermodynamic analysis of the GFP:GFP-nanobody complex

(2010) Marta H. Kubala et al.   PROTEIN SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal structure and association behaviour of the GluR2 amino-terminal domain

(2009) Rongsheng Jin et al.   EMBO JOURNAL

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

The Stoichiometry of AMPA Receptors and TARPs Varies by Neuronal Cell Type

(2009) Yun Shi et al.   NEURON

Subunit Composition of Synaptic AMPA Receptors Revealed by a Single-Cell Genetic Approach

(2009) Wei Lu et al.   NEURON

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH