Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8

(2016) Kevin M. Gardinier et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ−8 Through Investigations of TARP γ−8 Null Mice§

(2015) Scott Gleason et al.   CNS & Neurological Disorders-Drug Targets

The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy

(2015) Friederike Twele et al.   NEUROPHARMACOLOGY

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

(2012) Shigeki Hibi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neto1 and Neto2: auxiliary subunits that determine key properties of native kainate receptors

(2012) Susumu Tomita et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 304

(2012) J. A. French et al.   NEUROLOGY

Cornichon-2 Modulates AMPA Receptor-Transmembrane AMPA Receptor Regulatory Protein Assembly to Dictate Gating and Pharmacology

(2011) M. B. Gill et al.   JOURNAL OF NEUROSCIENCE

The Expanding Social Network of Ionotropic Glutamate Receptors: TARPs and Other Transmembrane Auxiliary Subunits

(2011) Alexander C. Jackson et al.   NEURON

Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia

(2011) K.G. Phillips et al.   NEUROPHARMACOLOGY

Hippocampal AMPA Receptor Gating Controlled by Both TARP and Cornichon Proteins

(2010) Akihiko S. Kato et al.   NEURON

Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating

(2010) Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtransplantation of ligand-gated receptor-channels from fresh or frozen nervous tissue into Xenopus oocytes: A potent tool for expanding functional information

(2009) F. Eusebi et al.   PROGRESS IN NEUROBIOLOGY

Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors

(2009) J. Schwenk et al.   SCIENCE

AMPA Receptor Subunit-Specific Regulation by a Distinct Family of Type II TARPs

(2008) Akihiko S. Kato et al.   NEURON

Stargazin modulates AMPA receptor antagonism

(2008) Barbara Cokić et al.   NEUROPHARMACOLOGY