Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy

Superactivation of AMPA receptors by auxiliary proteins

(2016) Anna L. Carbone et al.   Nature Communications

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Semi-automated selection of cryo-EM particles in RELION-1.3

(2015) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin

(2015) Y. Saitoh et al.   SCIENCE

Measuring the optimal exposure for single particle cryo-EM using a 2.6 Å reconstruction of rotavirus VP6

(2015) Timothy Grant et al.   eLife

Sampling the conformational space of the catalytic subunit of human γ-secretase

(2015) Xiao-chen Bai et al.   eLife

Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States

(2014) Katharina L. Dürr et al.   CELL

The Role of Ionotropic Glutamate Receptors in Childhood Neurodevelopmental Disorders: Autism Spectrum Disorders and Fragile X Syndrome

(2014) Genoveva Uzunova et al.   Current Neuropharmacology

Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors

(2014) Wei Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Stargazin promotes closure of the AMPA receptor ligand-binding domain

(2014) David M. MacLean et al.   JOURNAL OF GENERAL PHYSIOLOGY

Modulation of non-NMDA receptor gating by auxiliary subunits

(2014) James R. Howe   JOURNAL OF PHYSIOLOGY-LONDON

Mechanical coupling maintains the fidelity of NMDA receptor–mediated currents

(2014) Rashek Kazi et al.   NATURE NEUROSCIENCE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Structure of an agonist-bound ionotropic glutamate receptor

(2014) M. V. Yelshanskaya et al.   SCIENCE

Ultrastable gold substrates for electron cryomicroscopy

(2014) C. J. Russo et al.   SCIENCE

X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism

(2014) L. Chen et al.   SCIENCE

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

(2014) H. Suzuki et al.   SCIENCE

Mapping the Interaction Sites between AMPA Receptors and TARPs Reveals a Role for the Receptor N-Terminal Domain in Channel Gating

(2014) Ondrej Cais et al.   Cell Reports

Structure and gating of tetrameric glutamate receptors

(2013) Alexander I. Sobolevsky   JOURNAL OF PHYSIOLOGY-LONDON

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

AMPA receptor/TARP stoichiometry visualized by single-molecule subunit counting

(2013) P. Hastie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Insights from Glutamate Receptor Ion Channel Structures

(2012) Janesh Kumar et al.   Annual Review of Physiology

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

High-Resolution Proteomics Unravel Architecture and Molecular Diversity of Native AMPA Receptor Complexes

(2012) Jochen Schwenk et al.   NEURON

Phosphorylation and Assembly of Glutamate Receptors After Brain Ischemia

(2012) Fan Zhang et al.   STROKE

Stargazin (TARP  -2) Is Required for Compartment-Specific AMPA Receptor Trafficking and Synaptic Plasticity in Cerebellar Stellate Cells

(2011) A. C. Jackson et al.   JOURNAL OF NEUROSCIENCE

The Expanding Social Network of Ionotropic Glutamate Receptors: TARPs and Other Transmembrane Auxiliary Subunits

(2011) Alexander C. Jackson et al.   NEURON

Atomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptor

(2011) Hao Dong et al.   Nature Communications

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Assembly and Stoichiometry of the AMPA Receptor and Transmembrane AMPA Receptor Regulatory Protein Complex

(2010) K. S. Kim et al.   JOURNAL OF NEUROSCIENCE

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

TARPs differentially decorate AMPA receptors to specify neuropharmacology

(2010) Akihiko S. Kato et al.   TRENDS IN NEUROSCIENCES

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

The Stoichiometry of AMPA Receptors and TARPs Varies by Neuronal Cell Type

(2009) Yun Shi et al.   NEURON

Autoinactivation of Neuronal AMPA Receptors via Glutamate-Regulated TARP Interaction

(2009) Megumi Morimoto-Tomita et al.   NEURON

Glutamate mediates platelet activation through the AMPA receptor

(2008) Craig N. Morrell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

AMPA Receptor Subunit-Specific Regulation by a Distinct Family of Type II TARPs

(2008) Akihiko S. Kato et al.   NEURON

BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies

(2008) Abhiram Dukkipati et al.   PROTEIN EXPRESSION AND PURIFICATION