ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume -, Issue -, Pages 201817473
Publisher
Proceedings of the National Academy of Sciences
Online
2019-03-20
DOI
10.1073/pnas.1817473116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting lysyl oxidase reduces peritoneal fibrosis
- (2017) Christopher R. Harlow et al. PLoS One
- Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
- (2017) HaoRan Tang et al. Nature Communications
- Pre-clinical evaluation of small molecule LOXL2 inhibitors in breast cancer
- (2017) Joan Chang et al. Oncotarget
- Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
- (2017) Chen Rachman-Tzemah et al. Cell Reports
- A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance
- (2017) Sha Zhu et al. Journal of Cancer
- Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis
- (2017) Verena Aumiller et al. Scientific Reports
- Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis
- (2016) Thomas R. Cox et al. CANCER RESEARCH
- Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases
- (2016) Nancy Chan et al. CLINICAL CANCER RESEARCH
- Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma
- (2014) Carmen Chak-Lui Wong et al. HEPATOLOGY
- Copper is required for oncogenic BRAF signalling and tumorigenesis
- (2014) Donita C. Brady et al. NATURE
- Bioavailable copper modulates oxidative phosphorylation and growth of tumors
- (2013) S. Ishida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling
- (2012) Cheng-Yu Tsai et al. BIOCHEMICAL PHARMACOLOGY
- Charting the travels of copper in eukaryotes from yeast to mammals
- (2012) Tracy Nevitt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway
- (2012) Li-Ching Chen et al. BREAST CANCER RESEARCH AND TREATMENT
- Membrane Transporters as Determinants of the Pharmacology of Platinum Anticancer Drugs
- (2012) Johnson J. Liu et al. CURRENT CANCER DRUG TARGETS
- A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
- (2012) M. L. Turski et al. MOLECULAR AND CELLULAR BIOLOGY
- Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
- (2012) A-M Baker et al. ONCOGENE
- Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells
- (2012) XIAOXIAO YANG et al. ONCOLOGY REPORTS
- The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer
- (2011) Ann-Marie Baker et al. JNCI-Journal of the National Cancer Institute
- ATP7A-related copper transport diseases—emerging concepts and future trends
- (2011) Stephen G. Kaler Nature Reviews Neurology
- Role of lysyl oxidase in myocardial fibrosis: from basic science to clinical aspects
- (2010) Begoña López et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment
- (2010) Vivian Barry-Hamilton et al. NATURE MEDICINE
- Focal adhesion kinase-dependent regulation of adhesive forces involves vinculin recruitment to focal adhesions
- (2009) David W. Dumbauld et al. BIOLOGY OF THE CELL
- An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients
- (2009) Balazs Györffy et al. BREAST CANCER RESEARCH AND TREATMENT
- Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
- (2009) Janine T. Erler et al. CANCER CELL
- Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
- (2009) Kandice R. Levental et al. CELL
- Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
- (2008) Subba Rao Gangi Setty et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started