Naringenin, a dietary flavanone, enhances insulin-like growth factor 1 receptor-mediated antioxidant defense and attenuates methylglyoxal-induced neurite damage and apoptotic death

Isolated mangiferin and naringenin exert antidiabetic effect via PPAR γ /GLUT4 dual agonistic action with strong metabolic regulation

(2018) Ashok K. Singh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Impaired peripheral nerve regeneration in type-2 diabetic mouse model

(2018) Vuong M. Pham et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Metformin-like antidiabetic, cardio-protective and non-glycemic effects of naringenin: Molecular and pharmacological insights

(2017) Ntsoaki Annah Nyane et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Insulin-like growth factor-1 protects SH-SY5Y cells against β-amyloid-induced apoptosis via the PI3K/Akt-Nrf2 pathway

(2017) Zigao Wang et al.   EXPERIMENTAL GERONTOLOGY

Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons

(2017) Kaihua Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Flavonoid Naringenin Attenuates Oxidative Stress, Apoptosis and Improves Neurotrophic Effects in the Diabetic Rat Retina

(2017) Dalia Al-Dosari et al.   Nutrients

Cysteine persulfides and polysulfides produced by exchange reactions with H 2 S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

(2017) Shin Koike et al.   Redox Biology

Apigenin and naringenin regulate glucose and lipid metabolism, and ameliorate vascular dysfunction in type 2 diabetic rats

(2016) Bei Ren et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Naringenin pre-treatment inhibits neuroapoptosis and ameliorates cognitive impairment in rats exposed to isoflurane anesthesia by regulating the PI3/Akt/PTEN signalling pathway and suppressing NF-κB-mediated inflammation

(2016) Fu-Zhou Hua et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with açaí-enriched diets

(2016) Shibu M. Poulose et al.   NUTRITIONAL NEUROSCIENCE

Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy

(2016) Yu-Ting Tseng et al.   PHARMACOLOGICAL RESEARCH

Insulin resistance and Parkinson’s disease: A new target for disease modification?

(2016) D. Athauda et al.   PROGRESS IN NEUROBIOLOGY

High gastrointestinal permeability and local metabolism of naringenin: influence of antibiotic treatment on absorption and metabolism

(2015) Naiara Orrego-Lagarón et al.   BRITISH JOURNAL OF NUTRITION

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

(2015) Marcos Roberto de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Glutathione redox imbalance in brain disorders

(2015) Feng Gu et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Methylglyoxal, the dark side of glycolysis

(2015) Igor Allaman et al.   Frontiers in Neuroscience

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: Targets for disease modification?

(2014) Fares Bassil et al.   PROGRESS IN NEUROBIOLOGY

Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway

(2013) Haiyan Lou et al.   NEUROPHARMACOLOGY

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth

(2013) Ya-Yun Hsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement

(2013) Surangi Thilakarathna et al.   Nutrients

Triptolide increases transcript and protein levels of survival motor neurons in human SMA fibroblasts and improves survival in SMA-like mice

(2012) Ya-Yun Hsu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Citrus flavonoids and lipid metabolism

(2012) Julia M. Assini et al.   CURRENT OPINION IN LIPIDOLOGY

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E

(2011) F. Fiory et al.   DIABETOLOGIA

IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cells

(2011) Quan-Gui Gao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Analysis, Distribution, and Dietary Exposure of Glyoxal and Methylglyoxal in Cookies and Their Relationship with Other Heat-Induced Contaminants

(2010) Gema Arribas-Lorenzo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Methylglyoxal Content in Drinking Coffee as a Cytotoxic Factor

(2010) J. Wang et al.   JOURNAL OF FOOD SCIENCE

The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury

(2009) Katerina Vafeiadou et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons

(2007) Silvia Di Loreto et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY