Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death

Hydrophilicity Regulates the Stealth Properties of Polyphosphoester-Coated Nanocarriers

(2018) Johanna Simon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nrf2-Keap1 signaling in oxidative and reductive stress

(2018) Ilaria Bellezza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

HRI-mediated translational repression reduces proteotoxicity and sensitivity to bortezomib in human pancreatic cancer cells

(2018) Matthew C. White et al.   ONCOGENE

Immunological consequences of kidney cell death

(2018) Maysa Sarhan et al.   Cell Death & Disease

The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells

(2018) Mami Sato et al.   Scientific Reports

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

The Role of Ferroptosis in Cancer Development and Treatment Response

(2018) Bin Lu et al.   Frontiers in Pharmacology

Cytotoxicity of Poly(Alkyl Cyanoacrylate) Nanoparticles

(2017) Einar Sulheim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles

(2017) Ahmed Abdal Dayem et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stress-specific differences in assembly and composition of stress granules and related foci

(2017) Anaïs Aulas et al.   JOURNAL OF CELL SCIENCE

A review of endoplasmic reticulum (ER) stress and nanoparticle (NP) exposure

(2017) Yi Cao et al.   LIFE SCIENCES

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

Formation of the Protein Corona: The Interface between Nanoparticles and the Immune System

(2017) Francesco Barbero et al.   SEMINARS IN IMMUNOLOGY

Ultrasound Improves the Delivery and Therapeutic Effect of Nanoparticle-Stabilized Microbubbles in Breast Cancer Xenografts

(2017) Sofie Snipstad et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death

(2017) Omkar Zilka et al.   ACS Central Science

PIKfyve inhibition increases exosome release and induces secretory autophagy

(2016) Nina Pettersen Hessvik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

(2016) Haitao Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulated necrosis: disease relevance and therapeutic opportunities

(2016) Marcus Conrad et al.   NATURE REVIEWS DRUG DISCOVERY

Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells

(2016) K K Starheim et al.   Blood Cancer Journal

Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells

(2016) Cynthia Morata-Tarifa et al.   Scientific Reports

Cellular uptake and intracellular degradation of poly(alkyl cyanoacrylate) nanoparticles

(2016) Einar Sulheim et al.   JOURNAL OF NANOBIOTECHNOLOGY

Crosstalk between cystine and glutathione is critical for the regulation of amino acid signaling pathways and ferroptosis

(2016) Xinlei Yu et al.   Scientific Reports

Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery

(2015) Ýrr Mørch et al.   Contrast Media & Molecular Imaging

Cell death induced by endoplasmic reticulum stress

(2015) Raffaella Iurlaro et al.   FEBS Journal

Exploiting Intrinsic Nanoparticle Toxicity: The Pros and Cons of Nanoparticle-Induced Autophagy in Biomedical Research

(2014) Karen Peynshaert et al.   CHEMICAL REVIEWS

Drug delivery to the central nervous system by polymeric nanoparticles: What do we know?

(2013) Jörg Kreuter   ADVANCED DRUG DELIVERY REVIEWS

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

(2013) Luika A. Timmerman et al.   CANCER CELL

Pharmacological brake-release of mRNA translation enhances cognitive memory

(2013) Carmela Sidrauski et al.   eLife

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipids, curvature, and nano-medicine

(2011) Ole G. Mouritsen   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Oxidized Phospholipids Regulate Expression of ATF4 and VEGF in Endothelial Cells via NRF2-Dependent Mechanism: Novel Point of Convergence Between Electrophilic and Unfolded Protein Stress Pathways

(2010) Taras Afonyushkin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

The xc− cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases

(2008) Maisie Lo et al.   JOURNAL OF CELLULAR PHYSIOLOGY