Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

The antimicrobial activity of nanoparticles: present situation and prospects for the future

(2017) Linlin Wang et al.   International Journal of Nanomedicine

Protein corona: Opportunities and challenges

(2016) Saeid Zanganeh et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Meta-analysis of cellular toxicity for cadmium-containing quantum dots

(2016) Eunkeu Oh et al.   Nature Nanotechnology

Physical Principles of Nanoparticle Cellular Endocytosis

(2015) Sulin Zhang et al.   ACS Nano

Applications of nanoparticles for diagnosis and therapy of cancer

(2015) S C Baetke et al.   BRITISH JOURNAL OF RADIOLOGY

(Intra)Cellular Stability of Inorganic Nanoparticles: Effects on Cytotoxicity, Particle Functionality, and Biomedical Applications

(2015) Stefaan J. Soenen et al.   CHEMICAL REVIEWS

Nanoparticles in Photodynamic Therapy

(2015) Sasidharan Swarnalatha Lucky et al.   CHEMICAL REVIEWS

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

(2015) Hamed Arami et al.   CHEMICAL SOCIETY REVIEWS

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

(2015) Gopu Sriram et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Liver Toxicity of Cadmium Telluride Quantum Dots (CdTe QDs) Due to Oxidative Stress in Vitro and in Vivo

(2015) Ting Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Shape and surface effects on the cytotoxicity of nanoparticles: Gold nanospheres versus gold nanostars

(2015) Pelagie Marlene Favi et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Cytotoxicity and non-specific cellular uptake of bare and surface-modified upconversion nanoparticles in human skin cells

(2015) Anna E. Guller et al.   Nano Research

In vitro and in vivo toxicity studies of copper sulfide nanoplates for potential photothermal applications

(2015) Wei Feng et al.   Nanomedicine-Nanotechnology Biology and Medicine

Genotoxicity and gene expression modulation of silver and titanium dioxide nanoparticles in mice

(2015) Nana Asare et al.   Nanotoxicology

Mitochondrial Toxicity of Cadmium Telluride Quantum Dot Nanoparticles in Mammalian Hepatocytes

(2015) Kathy C. Nguyen et al.   TOXICOLOGICAL SCIENCES

Cell Type-Dependent Changes in CdSe/ZnS Quantum Dot Uptake and Toxic Endpoints

(2015) Bella B. Manshian et al.   TOXICOLOGICAL SCIENCES

Ultrasmall Gold Nanoparticles as Carriers for Nucleus-Based Gene Therapy Due to Size-Dependent Nuclear Entry

(2014) Shuaidong Huo et al.   ACS Nano

Research Advances on Apoptosis Caused by Quantum Dots

(2014) Qingling Zhan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Lectin-Tagged Fluorescent Polymeric Nanoparticles for Targeting of Sialic Acid on Living Cells

(2014) Jaebum Cho et al.   BIOMACROMOLECULES

A New X-Ray Activated Nanoparticle Photosensitizer for Cancer Treatment

(2014) Lun Ma et al.   Journal of Biomedical Nanotechnology

Mechanisms of Nanoparticle Internalization and Transport Across an Intestinal Epithelial Cell Model: Effect of Size and Surface Charge

(2014) Azzah M. Bannunah et al.   MOLECULAR PHARMACEUTICS

Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects

(2014) Sutapa Barua et al.   Nano Today

In vitro investigation of silica nanoparticle uptake into human endothelial cells under physiological cyclic stretch

(2014) Christian Freese et al.   Particle and Fibre Toxicology

Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

(2014) E. Phillips et al.   Science Translational Medicine

Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles

(2014) Cindy Gunawan et al.   Journal of Materials Chemistry B

Casein-Coated Iron Oxide Nanoparticles for High MRI Contrast Enhancement and Efficient Cell Targeting

(2013) Jing Huang et al.   ACS Applied Materials & Interfaces

Functionalization-Dependent Induction of Cellular Survival Pathways by CdSe Quantum Dots in Primary Normal Human Bronchial Epithelial Cells

(2013) Amber Nagy et al.   ACS Nano

Polymer-Coated Nanoparticles Interacting with Proteins and Cells: Focusing on the Sign of the Net Charge

(2013) Dominik Hühn et al.   ACS Nano

Convective diffusion of nanoparticles from the epithelial barrier toward regional lymph nodes

(2013) Stanislav S. Dukhin et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Nanoparticles, Lung Injury, and the Role of Oxidant Stress

(2013) Amy K. Madl et al.   Annual Review of Physiology

Inflammation-Responsive Antioxidant Nanoparticles Based on a Polymeric Prodrug of Vanillin

(2013) Jeongil Kwon et al.   BIOMACROMOLECULES

Cellular uptake, elimination and toxicity of CdSe/ZnS quantum dots in HepG2 cells

(2013) Lu Peng et al.   BIOMATERIALS

Biodistribution, pharmacokinetics and toxicology of Ag2S near-infrared quantum dots in mice

(2013) Yan Zhang et al.   BIOMATERIALS

Toxicity of commercially available engineered nanoparticles to Caco-2 and SW480 human intestinal epithelial cells

(2013) Talia E. Abbott Chalew et al.   CELL BIOLOGY AND TOXICOLOGY

In Vitro Cytotoxicity of Fluorescent Silica Nanoparticles Hybridized with Aggregation-Induced Emission Luminogens for Living Cell Imaging

(2013) Yun Xia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interaction between silver nanoparticles of 20 nm (AgNP20) and human neutrophils: induction of apoptosis and inhibition ofde novoprotein synthesis by AgNP20aggregates

(2013) Michelle Poirier et al.   JOURNAL OF APPLIED TOXICOLOGY

ZnO nanoparticles induce TNF-α expression via ROS-ERK-Egr-1 pathway in human keratinocytes

(2013) Sang Hoon Jeong et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Poly-(ethylene glycol) modified gelatin nanoparticles for sustained delivery of the anti-inflammatory drug Ibuprofen-Sodium: An in vitro and in vivo analysis

(2013) Dhanya Narayanan et al.   Nanomedicine-Nanotechnology Biology and Medicine

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes

(2013) Fengjuan Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Degradation of aqueous synthesized CdTe/ZnS quantum dots in mice: differential blood kinetics and biodistribution of cadmium and tellurium

(2013) Na Liu et al.   Particle and Fibre Toxicology

Surface modification of inorganic nanoparticles for development of organic–inorganic nanocomposites—A review

(2013) Sarita Kango et al.   PROGRESS IN POLYMER SCIENCE

Assessment of in vitro cellular responses of monocytes and keratinocytes to tannic acid modified silver nanoparticles

(2013) Piotr Orlowski et al.   TOXICOLOGY IN VITRO

Vaccine delivery using nanoparticles

(2013) Anthony E. Gregory et al.   Frontiers in Cellular and Infection Microbiology

Are Quantum Dots Toxic? Exploring the Discrepancy Between Cell Culture and Animal Studies

(2012) Kim M. Tsoi et al.   ACCOUNTS OF CHEMICAL RESEARCH

Comprehensive Analysis of the Effects of CdSe Quantum Dot Size, Surface Charge, and Functionalization on Primary Human Lung Cells

(2012) Amber Nagy et al.   ACS Nano

Cellular Uptake of Nanoparticles by Membrane Penetration: A Study Combining Confocal Microscopy with FTIR Spectroelectrochemistry

(2012) Tiantian Wang et al.   ACS Nano

Cytotoxicity of hydroxyapatite nanoparticles is shape and cell dependent

(2012) Xinxin Zhao et al.   ARCHIVES OF TOXICOLOGY

ROS-mediated apoptotic cell death in prostate cancer LNCaP cells induced by biosurfactant stabilized CdS quantum dots

(2012) Braj R. Singh et al.   BIOMATERIALS

The effects of luminescent ruthenium(II) polypyridyl functionalized selenium nanoparticles on bFGF-induced angiogenesis and AKT/ERK signaling

(2012) Dongdong Sun et al.   BIOMATERIALS

Nanotoxicity assessment of quantum dots: from cellular to primate studies

(2012) Ken-Tye Yong et al.   CHEMICAL SOCIETY REVIEWS

Degradation Products from Consumer Nanocomposites: A Case Study on Quantum Dot Lighting

(2012) Jingyu Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Acute toxicity and tissue distribution of CdSe/CdS-MPA quantum dots after repeated intraperitoneal injection to mice

(2012) Md. Mamunul Haque et al.   JOURNAL OF APPLIED TOXICOLOGY

Nanostructured lipid carriers system: Recent advances in drug delivery

(2012) Md Asif Iqbal et al.   JOURNAL OF DRUG TARGETING

The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells

(2012) Fiona A Murphy et al.   Particle and Fibre Toxicology

Cytotoxic effects in 3T3-L1 mouse and WI-38 human fibroblasts following 72hour and 7day exposures to commercial silica nanoparticles

(2012) Maciej Stępnik et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Microfluidic 3D cell culture: potential application for tissue-based bioassays

(2012) XiuJun (James) Li et al.   Bioanalysis

PEGylated Phospholipid Micelle-Encapsulated Near-Infrared PbS Quantum Dots for in vitro and in vivo Bioimaging

(2012) Rui Hu et al.   Theranostics

Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis

(2011) Nobutaka Hanagata et al.   ACS Nano

Protein Corona-Mediated Mitigation of Cytotoxicity of Graphene Oxide

(2011) Wenbing Hu et al.   ACS Nano

Characterization of Translocation of Silver Nanoparticles and Effects on Whole-Genome Gene Expression Using an In Vitro Intestinal Epithelium Coculture Model

(2011) Hans Bouwmeester et al.   ACS Nano

Interaction of Mesoporous Silica Nanoparticles with Human Red Blood Cell Membranes: Size and Surface Effects

(2011) Yannan Zhao et al.   ACS Nano

Intracellular dynamics of cationic and anionic polystyrene nanoparticles without direct interaction with mitotic spindle and chromosomes

(2011) Yuexian Liu et al.   BIOMATERIALS

Mechanisms underlying toxicity induced by CdTe quantum dots determined in an invertebrate model organism

(2011) Alfredo Ambrosone et al.   BIOMATERIALS

The cytotoxicity of cadmium-based quantum dots

(2011) Nan Chen et al.   BIOMATERIALS

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

(2011) Carl D. Walkey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualizing Gold Nanoparticle Uptake in Live Cells with Liquid Scanning Transmission Electron Microscopy

(2011) Diana B. Peckys et al.   NANO LETTERS

Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

(2011) Stefaan J. Soenen et al.   Nano Today

Experimental considerations on the cytotoxicity of nanoparticles

(2011) Bokyung Kong et al.   Nanomedicine

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

(2011) Jean-Pascal Piret et al.   Nanotoxicology

Respiratory epithelial cytotoxicity and membrane damage (holes) caused by amine-modified nanoparticles

(2011) Pakatip Ruenraroengsak et al.   Nanotoxicology

Development and haematotoxicological evaluation of doped hydroxyapatite based multimodal nanocontrast agent for near-infrared, magnetic resonance and X-ray contrast imaging

(2011) Anusha Ashokan et al.   Nanotoxicology

Neurological impacts from inhalation of pollutants and the nose–brain connection

(2011) R.G. Lucchini et al.   NEUROTOXICOLOGY

Aerosolized ZnO Nanoparticles Induce Toxicity in Alveolar Type II Epithelial Cells at the Air-Liquid Interface

(2011) Yumei Xie et al.   TOXICOLOGICAL SCIENCES

Physicochemical Characterization and In Vitro Hemolysis Evaluation of Silver Nanoparticles

(2011) Jonghoon Choi et al.   TOXICOLOGICAL SCIENCES

An in vitro study of vascular endothelial toxicity of CdTe quantum dots

(2011) Ming Yan et al.   TOXICOLOGY

Synthesis and characterisation of biologically compatible TiO2 nanoparticles

(2011) Richard W Cheyne et al.   Nanoscale Research Letters

Nanoparticle-Induced Apoptosis Propagates through Hydrogen-Peroxide-Mediated Bystander Killing: Insights from a Human Intestinal Epithelium In Vitro Model

(2010) Anupama Thubagere et al.   ACS Nano

Surface-Charge-Dependent Cell Localization and Cytotoxicity of Cerium Oxide Nanoparticles

(2010) Atul Asati et al.   ACS Nano

Cadmium-Free CuInS2/ZnS Quantum Dots for Sentinel Lymph Node Imaging with Reduced Toxicity

(2010) Thomas Pons et al.   ACS Nano

In Vivo Targeted Cancer Imaging, Sentinel Lymph Node Mapping and Multi-Channel Imaging with Biocompatible Silicon Nanocrystals

(2010) Folarin Erogbogbo et al.   ACS Nano

c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy

(2010) Henrike Peuschel et al.   BIOLOGICAL CHEMISTRY

Use of a Clinically Approved Iron Oxide MRI Contrast Agent to Label Human Hepatocytes

(2010) Juliana Puppi et al.   CELL TRANSPLANTATION

Surface Charge-Dependent Toxicity of Silver Nanoparticles

(2010) Amro M. El Badawy et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Toxic effects of iron oxide nanoparticles on human umbilical vein endothelial cells

(2010) Wu et al.   International Journal of Nanomedicine

Toxicologic effects of gold nanoparticles in vivo by different administration routes

(2010) Zhang   International Journal of Nanomedicine

Gene expression profiling reveals early cellular responses to intracellular magnetic labeling with superparamagnetic iron oxide nanoparticles

(2010) Dorota A. Kedziorek et al.   MAGNETIC RESONANCE IN MEDICINE

Silver nanoparticles as a safe preservative for use in cosmetics

(2010) Satoshi Kokura et al.   Nanomedicine-Nanotechnology Biology and Medicine

Degradability of superparamagnetic nanoparticles in a model of intracellular environment: follow-up of magnetic, structural and chemical properties

(2010) Michael Lévy et al.   NANOTECHNOLOGY

Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity

(2010) Raymond F Hamilton et al.   Particle and Fibre Toxicology

Toxicological Aspects of Long-Term Treatment of Keratinocytes with ZnO and TiO2 Nanoparticles

(2010) Petra Kocbek et al.   Small

The inhibitory effect of superparamagnetic iron oxide nanoparticle (Ferucarbotran) on osteogenic differentiation and its signaling mechanism in human mesenchymal stem cells

(2010) Ying-Chun Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

ROS-mediated genotoxicity induced by titanium dioxide nanoparticles in human epidermal cells

(2010) Ritesh K. Shukla et al.   TOXICOLOGY IN VITRO

Near infrared imaging with nanoparticles

(2010) Erhan İ. Altınoğlu et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Polymers for Drug Delivery Systems

(2010) William B. Liechty et al.   Annual Review of Chemical and Biomolecular Engineering

Hybrid Antimicrobial Enzyme and Silver Nanoparticle Coatings for Medical Instruments

(2009) D. Matthew Eby et al.   ACS Applied Materials & Interfaces

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Potential Health Impact of Nanoparticles

(2009) Tian Xia et al.   Annual Review of Public Health

Toxicity and Developmental Defects of Different Sizes and Shape Nickel Nanoparticles in Zebrafish

(2009) Cristina Ispas et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Nanoparticle-based targeted drug delivery

(2009) Rajesh Singh et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Toxicological effects of inorganic nanoparticles on human lung cancer A549 cells

(2009) Soo-Jin Choi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cell Uptake andin VitroToxicity of Magnetic Nanoparticles Suitable for Drug Delivery

(2009) Urs O. Häfeli et al.   MOLECULAR PHARMACEUTICS

Long-term Persistence and Spectral Blue Shifting of Quantum Dots in Vivo

(2009) James A. J. Fitzpatrick et al.   NANO LETTERS

Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis

(2009) Sebastien Vankoningsloo et al.   Nanotoxicology

Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells

(2009) Kirsten Gerloff et al.   Nanotoxicology

Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

(2009) Sophie Lanone et al.   Particle and Fibre Toxicology

Cellular Uptake and Cytotoxicity of Gold Nanorods: Molecular Origin of Cytotoxicity and Surface Effects

(2009) Alaaldin M. Alkilany et al.   Small

In vivo Quantum-Dot Toxicity Assessment

(2009) Tanya S. Hauck et al.   Small

Effects and uptake of gold nanoparticles deposited at the air–liquid interface of a human epithelial airway model

(2009) C. Brandenberger et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Experimental approach for an in vitro toxicity assay with non-aggregated quantum dots

(2009) Brian A. Koeneman et al.   TOXICOLOGY IN VITRO

Cytotoxicity of carboxylic acid functionalized single wall carbon nanotubes on the human intestinal cell line Caco-2

(2009) Angeles Jos et al.   TOXICOLOGY IN VITRO

Cytotoxicity of nanostructured vanadium oxide on human cells in vitro

(2009) Laura S. Rhoads et al.   TOXICOLOGY IN VITRO

In vitro mammalian cytotoxicological study of PAMAM dendrimers – Towards quantitative structure activity relationships

(2009) Sourav Prasanna Mukherjee et al.   TOXICOLOGY IN VITRO

Particle size-dependent organ distribution of gold nanoparticles after intravenous administration

(2008) Wim H. De Jong et al.   BIOMATERIALS

The relevance of shape and size of Au55 clusters

(2008) Günter Schmid   CHEMICAL SOCIETY REVIEWS

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Cell Culture Matrices: State of the Art

(2008) Jungwoo Lee et al.   TISSUE ENGINEERING PART B-REVIEWS

Particokinetics and Extrapulmonary Translocation of Intratracheally Instilled Ferric Oxide Nanoparticles in Rats and the Potential Health Risk Assessment

(2008) Mo-Tao Zhu et al.   TOXICOLOGICAL SCIENCES

Biological interactions of quantum dot nanoparticles in skin and in human epidermal keratinocytes

(2008) L ZHANG et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS

Toxicity of CdSe Nanoparticles in Caco-2 Cell Cultures

(2008) Lin Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY