Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation

Iso-α-acids, the bitter components of beer, improve hippocampus-dependent memory through vagus nerve activation

(2019) Yasuhisa Ano et al.   FASEB JOURNAL

Depression: the radical theory linking it to inflammation

(2018) Alison Abbott   NATURE

Pattern of polyphenol intake and the long-term risk of dementia in older persons

(2018) Sophie Lefèvre-Arbogast et al.   NEUROLOGY

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation

(2018) Xiang Nie et al.   NEURON

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

(2018) Laetitia Weinhard et al.   Nature Communications

Novel lactopeptides in fermented dairy products improve memory function and cognitive decline

(2018) Yasuhisa Ano et al.   NEUROBIOLOGY OF AGING

Iso-α-Acids, the Bitter Components of Beer, Suppress Microglial Inflammation in rTg4510 Tauopathy

(2018) Yasuhisa Ano et al.   MOLECULES

In vitro and in vivo anti-inflammatory effects of theaflavin-3,3′-digallate on lipopolysaccharide-induced inflammation

(2017) Yanting Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

EGCG ameliorates high-fat– and high-fructose–induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS

(2017) Yashi Mi et al.   FASEB JOURNAL

Iso-α-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease

(2017) Yasuhisa Ano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

(−)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer’s disease

(2017) Yufang Guo et al.   NEUROREPORT

Cytokine signature associated with disease severity in chronic fatigue syndrome patients

(2017) Jose G. Montoya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association between tea consumption and risk of cognitive disorders: A dose-response meta-analysis of observational studies

(2017) Xueying Liu et al.   Oncotarget

Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases

(2017) Björn Spittau   Frontiers in Aging Neuroscience

Inflammation in Depression and the Potential for Anti-Inflammatory Treatment

(2016) Ole Kohler et al.   Current Neuropharmacology

Tea consumption and health-related quality of life in older adults

(2016) C.-W. Pan et al.   Journal of Nutrition Health & Aging

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

(2016) Nicholas H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Spines in Depression: What We Learned from Animal Models

(2016) Hui Qiao et al.   NEURAL PLASTICITY

Antiviral activity of theaflavin digallate against herpes simplex virus type 1

(2015) Aline de Oliveira et al.   ANTIVIRAL RESEARCH

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

(2015) Ji-chun Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

The role of inflammation and microglial activation in the pathophysiology of psychiatric disorders

(2015) G.Z. Réus et al.   NEUROSCIENCE

Preventive Effects of a Fermented Dairy Product against Alzheimer’s Disease and Identification of a Novel Oleamide with Enhanced Microglial Phagocytosis and Anti-Inflammatory Activity

(2015) Yasuhisa Ano et al.   PLoS One

Identification of a Novel Dehydroergosterol Enhancing Microglial Anti-Inflammatory Activity in a Dairy Product Fermented with Penicillium candidum

(2015) Yasuhisa Ano et al.   PLoS One

Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An 11C-(R)-PK11195 PET Study

(2014) Y. Nakatomi et al.   JOURNAL OF NUCLEAR MEDICINE

Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

(2013) Marcus A Lawson et al.   Journal of Neuroinflammation

Molecular mechanisms of dendrite stability

(2013) Anthony J. Koleske   NATURE REVIEWS NEUROSCIENCE

Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair

(2013) Anat London et al.   Frontiers in Cellular Neuroscience

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

(2012) Young-Jung Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Evaluation of the antioxidant effects of four main theaflavin derivatives through chemiluminescence and DNA damage analyses

(2011) Yuan-yuan Wu et al.   Journal of Zhejiang University-SCIENCE B

Green tea polyphenols produce antidepressant-like effects in adult mice

(2011) Wei-Li Zhu et al.   PHARMACOLOGICAL RESEARCH

The functional neuroanatomy of depression: Distinct roles for ventromedial and dorsolateral prefrontal cortex

(2009) Michael Koenigs et al.   BEHAVIOURAL BRAIN RESEARCH

Radical-scavenging abilities and antioxidant properties of theaflavins and their gallate esters in H2O2-mediated oxidative damage system in the HPF-1 cells

(2008) Ziyin Yang et al.   TOXICOLOGY IN VITRO

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL