Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

Indoleamine 2,3-dioxygenase inhibition attenuates lipopolysaccharide induced persistent microglial activation and depressive-like complications in fractalkine receptor (CX3CR1)-deficient mice

(2012) Angela W. Corona et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of 1-methyltryptophan stereoisomers on IDO2 enzyme activity and IDO2-mediated arrest of human T cell proliferation

(2012) Feng Qian et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Kynurenines: from the perspective of major psychiatric disorders

(2012) Aye M. Myint   FEBS Journal

Indoleamine 2,3-dioxygenase mediates anhedonia and anxiety-like behaviors caused by peripheral lipopolysaccharide immune challenge

(2012) Alexander Salazar et al.   HORMONES AND BEHAVIOR

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Intracerebroventricular administration of HIV-1 Tat induces brain cytokine and indoleamine 2,3-dioxygenase expression: A possible mechanism for AIDS comorbid depression

(2011) Marcus A. Lawson et al.   BRAIN BEHAVIOR AND IMMUNITY

Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide

(2011) Sook-Eun Park et al.   Journal of Neuroinflammation

Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice

(2011) Sook-Eun Park et al.   Journal of Neuroinflammation

Multiple sclerosis and depression

(2011) Anthony Feinstein   Multiple Sclerosis Journal

Depression in Parkinson disease—epidemiology, mechanisms and management

(2011) Dag Aarsland et al.   Nature Reviews Neurology

Depressive-like behavior induced by tumor necrosis factor-α in mice

(2011) Manuella P. Kaster et al.   NEUROPHARMACOLOGY

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior in Vivo and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

(2010) Xin Fu et al.   Journal of Neuroinflammation

Animal models of neuropsychiatric disorders

(2010) Eric J Nestler et al.   NATURE NEUROSCIENCE

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

Interferon-  and Tumor Necrosis Factor-  Mediate the Upregulation of Indoleamine 2,3-Dioxygenase and the Induction of Depressive-Like Behavior in Mice in Response to Bacillus Calmette-Guerin

(2009) J. C. O'Connor et al.   JOURNAL OF NEUROSCIENCE

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

(2009) Masaaki Kanai et al.   Molecular Brain

IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism

(2008) Stefan Löb et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE