EGCG ameliorates high-fat– and high-fructose–induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS

The Major Green Tea Polyphenol, (-)-Epigallocatechin-3-Gallate, Inhibits Obesity, Metabolic Syndrome, and Fatty Liver Disease in High-Fat–Fed Mice

(2018) Mousumi Bose et al.   JOURNAL OF NUTRITION

Sesamol ameliorates high-fat and high-fructose induced cognitive defects via improving insulin signaling disruption in the central nervous system

(2017) Zhigang Liu et al.   Food & Function

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome

(2016) Baokun He et al.   Cell Metabolism

Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF)

(2016) Yoni Genzer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Green tea (-)-epigallocatechin-3-gallate counteracts daytime overeating induced by high-fat diet in mice

(2016) Hongyu Li et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Agavins Increase Neurotrophic Factors and Decrease Oxidative Stress in the Brains of High-Fat Diet-Induced Obese Mice

(2016) Elena Franco-Robles et al.   MOLECULES

Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance

(2015) Pedro Cisternas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock

(2015) Gad Asher et al.   CELL

Dietary Polyphenols Promote Growth of the Gut BacteriumAkkermansia muciniphilaand Attenuate High-Fat Diet–Induced Metabolic Syndrome

(2015) Diana E. Roopchand et al.   DIABETES

Neuroprotective Properties of the Standardized Extract fromCamellia sinensis(Green Tea) and Its Main Bioactive Components, Epicatechin and Epigallocatechin Gallate, in the 6-OHDA Model of Parkinson’s Disease

(2015) Natália Bitu Pinto et al.   Evidence-based Complementary and Alternative Medicine

Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine-Induced HepG2 Cells

(2015) Di Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

High-Fat Diet Induces Hepatic Insulin Resistance and Impairment of Synaptic Plasticity

(2015) Zhigang Liu et al.   PLoS One

Disruption of Daily Rhythms by High-Fat Diet Is Reversible

(2015) Katrina L. Branecky et al.   PLoS One

Large, binge-type meals of high fat diet change feeding behaviour and entrain food anticipatory activity in mice☆

(2014) T. Bake et al.   APPETITE

Circadian regulation of metabolism

(2014) Shannon M Bailey et al.   JOURNAL OF ENDOCRINOLOGY

Insulin and IGF receptor signalling in neural-stem-cell homeostasis

(2014) Amber N. Ziegler et al.   Nature Reviews Endocrinology

High fat diet produces brain insulin resistance, synaptodendritic abnormalities and altered behavior in mice

(2014) Steven E. Arnold et al.   NEUROBIOLOGY OF DISEASE

Reprogramming of the Circadian Clock by Nutritional Challenge

(2013) Kristin L. Eckel-Mahan et al.   CELL

BDNF and memory processing

(2013) Pedro Bekinschtein et al.   NEUROPHARMACOLOGY

GDNF, NGF and BDNF as therapeutic options for neurodegeneration

(2013) Shelley J. Allen et al.   PHARMACOLOGY & THERAPEUTICS

BDNF and the central control of feeding: accidental bystander or essential player?

(2013) Maribel Rios   TRENDS IN NEUROSCIENCES

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Brain Insulin Resistance and Deficiency as Therapeutic Targets in Alzheimers Disease

(2012) Suzanne M. de la Monte   Current Alzheimer Research

Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications

(2011) Brahma N. Singh et al.   BIOCHEMICAL PHARMACOLOGY

PPARγ Agonist Improves Neuronal Insulin Receptor Function in Hippocampus and Brain Mitochondria Function in Rats with Insulin Resistance Induced by Long Term High-Fat Diets

(2011) Noppamas Pipatpiboon et al.   ENDOCRINOLOGY

Adult neurogenesis and the plasticity of the dentate gyrus network

(2011) Lucas A. Mongiat et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes

(2011) Shunming Zhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Immunity as a link between obesity and insulin resistance

(2011) Nishan S. Kalupahana et al.   MOLECULAR ASPECTS OF MEDICINE

Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action☆

(2010) Siddharth Sukumaran et al.   ADVANCED DRUG DELIVERY REVIEWS

Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes

(2010) Laura D. Baker et al.   ARCHIVES OF NEUROLOGY

An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice

(2010) L. A. Sadacca et al.   DIABETOLOGIA

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

(2009) Jean-François Tanti et al.   CURRENT OPINION IN PHARMACOLOGY

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Aβ1-42 oligomers and upregulating synaptic plasticity–related proteins in the hippocampus

(2009) Q. Li et al.   NEUROSCIENCE

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

(2009) Swarup K. Chakrabarti et al.   Obesity

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

The Meter of Metabolism

(2008) Carla B. Green et al.   CELL

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY