SCRaMbLE generates evolved yeasts with increased alkali tolerance

Heterozygous diploid and interspecies SCRaMbLEing

(2018) Michael J. Shen et al.   Nature Communications

Rapid host strain improvement by in vivo rearrangement of a synthetic yeast chromosome

(2018) B. A. Blount et al.   Nature Communications

Precise control of SCRaMbLE in synthetic haploid and diploid yeast

(2018) Bin Jia et al.   Nature Communications

In vitro DNA SCRaMbLE

(2018) Yi Wu et al.   Nature Communications

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

(2018) Wei Liu et al.   Nature Communications

Identifying and characterizing SCRaMbLEd synthetic yeast using ReSCuES

(2018) Zhouqing Luo et al.   Nature Communications

Genome evolution across 1,011 Saccharomyces cerevisiae isolates

(2018) Jackson Peter et al.   NATURE

Ring synthetic chromosome V SCRaMbLE

(2018) Juan Wang et al.   Nature Communications

Improving prodeoxyviolacein production via multiplex SCRaMbLE iterative cycles

(2018) Juan Wang et al.   Frontiers of Chemical Science and Engineering

Bug mapping and fitness testing of chemically synthesized chromosome X

(2017) Yi Wu et al.   SCIENCE

3D organization of synthetic and scrambled chromosomes

(2017) Guillaume Mercy et al.   SCIENCE

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome

(2017) Yue Shen et al.   SCIENCE

Engineering the ribosomal DNA in a megabase synthetic chromosome

(2017) Weimin Zhang et al.   SCIENCE

Design of a synthetic yeast genome

(2017) Sarah M. Richardson et al.   SCIENCE

Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond

(2017) Leslie A. Mitchell et al.   SCIENCE

“Perfect” designer chromosome V and behavior of a ring derivative

(2017) Ze-Xiong Xie et al.   SCIENCE

Adaptive potential of genomic structural variation in human and mammalian evolution

(2015) David W. Radke et al.   Briefings in Functional Genomics

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

(2015) Yue Shen et al.   GENOME RESEARCH

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Casein Kinase 2 Associates with the Yeast Chromatin Reassembly Factor Spt2/Sin1 To Regulate Its Function in the Repression of Spurious Transcription

(2013) W. Bhat et al.   MOLECULAR AND CELLULAR BIOLOGY

Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

(2013) Wei Li et al.   NATURE BIOTECHNOLOGY

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Transcription Regulation by the Noncoding RNA SRG1 Requires Spt2-Dependent Chromatin Deposition in the Wake of RNA Polymerase II

(2011) P. Thebault et al.   MOLECULAR AND CELLULAR BIOLOGY

Different sets of QTLs influence fitness variation in yeast

(2010) Gal Hagit Romano et al.   Molecular Systems Biology

Yeast evolutionary genomics

(2010) Bernard Dujon   NATURE REVIEWS GENETICS

The Mother Enrichment Program: A Genetic System for Facile Replicative Life Span Analysis in Saccharomyces cerevisiae

(2009) D. L. Lindstrom et al.   GENETICS