3D organization of synthetic and scrambled chromosomes

Bug mapping and fitness testing of chemically synthesized chromosome X

(2017) Yi Wu et al.   SCIENCE

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome

(2017) Yue Shen et al.   SCIENCE

Engineering the ribosomal DNA in a megabase synthetic chromosome

(2017) Weimin Zhang et al.   SCIENCE

Design of a synthetic yeast genome

(2017) Sarah M. Richardson et al.   SCIENCE

Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond

(2017) Leslie A. Mitchell et al.   SCIENCE

“Perfect” designer chromosome V and behavior of a ring derivative

(2017) Ze-Xiong Xie et al.   SCIENCE

Contact genomics: scaffolding and phasing (meta)genomes using chromosome 3D physical signatures

(2015) Jean-François Flot et al.   FEBS LETTERS

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

(2015) Yue Shen et al.   GENOME RESEARCH

The Conformation of Yeast Chromosome III Is Mating Type Dependent and Controlled by the Recombination Enhancer

(2015) Jon-Matthew Belton et al.   Cell Reports

Filling annotation gaps in yeast genomes using genome-wide contact maps

(2014) Hervé Marie-Nelly et al.   BIOINFORMATICS

3D genome reconstruction from chromosomal contacts

(2014) Annick Lesne et al.   NATURE METHODS

Total Synthesis of a Functional Designer Eukaryotic Chromosome

(2014) N. Annaluru et al.   SCIENCE

High-quality genome (re)assembly using chromosomal contact data

(2014) Hervé Marie-Nelly et al.   Nature Communications

High-throughput genome scaffolding from in vivo DNA interaction frequency

(2013) Noam Kaplan et al.   NATURE BIOTECHNOLOGY

Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions

(2013) Joshua N Burton et al.   NATURE BIOTECHNOLOGY

Normalization of a chromosomal contact map

(2012) Axel Cournac et al.   BMC GENOMICS

Structure and Function in the Budding Yeast Nucleus

(2012) A. Taddei et al.   GENETICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The Saccharomyces cerevisiae SCRaMbLE system and genome minimization

(2012) Jessica Dymond et al.   Bioengineered

Synthetic chromosome arms function in yeast and generate phenotypic diversity by design

(2011) Jessica S. Dymond et al.   NATURE

A three-dimensional model of the yeast genome

(2010) Zhijun Duan et al.   NATURE

Chromosome arm length and nuclear constraints determine the dynamic relationship of yeast subtelomeres

(2010) P. Therizols et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Yeast Silent Mating Type Loci Form Heterochromatic Clusters through Silencer Protein-Dependent Long-Range Interactions

(2009) Adriana Miele et al.   PLoS Genetics

Controlled exchange of chromosomal arms reveals principles driving telomere interactions in yeast

(2007) H. Schober et al.   GENOME RESEARCH