β-adrenergic-mediated dynamic augmentation of sarcolemmal CaV 1.2 clustering and co-operativity in ventricular myocytes

Dynamic L-type Ca V 1.2 channel trafficking facilitates Ca V 1.2 clustering and cooperative gating

(2018) Debapriya Ghosh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A model for cooperative gating of L-type Ca2+ channels and its effects on cardiac alternans dynamics

(2018) Daisuke Sato et al.   PLoS Computational Biology

Cardiac CaV1.2 channels require β subunits for β-adrenergic–mediated modulation but not trafficking

(2018) Lin Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of CaV1.2 calcium channels in hippocampal neurons

(2017) Alessandra Folci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional selectivity of GPCR-directed drug action through location bias

(2017) Roshanak Irannejad et al.   Nature Chemical Biology

Voltage-gated sodium channels assemble and gate as dimers

(2017) Jérôme Clatot et al.   Nature Communications

Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)–Organized DyadsCLINICAL PERSPECTIVE

(2016) Ying Fu et al.   CIRCULATION

Oxidative stress decreases microtubule growth and stability in ventricular myocytes

(2016) Benjamin M.L. Drum et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Extensive phosphorylation of AMPA receptors in neurons

(2016) Graham H. Diering et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast live-cell conventional fluorophore nanoscopy with ImageJ through super-resolution radial fluctuations

(2016) Nils Gustafsson et al.   Nature Communications

Ca2+ entry into neurons is facilitated by cooperative gating of clustered CaV1.3 channels

(2016) Claudia M Moreno et al.   eLife

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   JOURNAL OF PHYSIOLOGY-LONDON

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention

(2015) Shaohua Xiao et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Graded Ca2+/calmodulin-dependent coupling of voltage-gated CaV1.2 channels

(2015) Rose E Dixon et al.   eLife

Phosphorylation of the AMPA receptor GluA1 subunit regulates memory load capacity

(2014) Laura Olivito et al.   Brain Structure & Function

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

Super-resolution Scanning Patch Clamp Reveals Clustering of Functional Ion Channels in Adult Ventricular Myocyte

(2013) Anamika Bhargava et al.   CIRCULATION RESEARCH

Regulation of Cardiac L-Type Ca 2+ Channel Ca V 1.2 Via the β-Adrenergic-cAMP-Protein Kinase A Pathway

(2013) Sharon Weiss et al.   CIRCULATION RESEARCH

[Ca2+]iElevation and Oxidative Stress Induce KCNQ1 Protein Translocation from the Cytosol to the Cell Surface and Increase Slow Delayed Rectifier (IKs) in Cardiac Myocytes

(2013) Yuhong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Competition between α-actinin and Ca2+-Calmodulin Controls Surface Retention of the L-type Ca2+ Channel CaV1.2

(2013) Duane D. Hall et al.   NEURON

Capturing single L-type Ca2+ channel function with optics

(2012) Matthew A. Nystoriak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization

(2012) Halina S. Chkourko et al.   HEART RHYTHM

Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel

(2012) Julia Brandmayr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels

(2012) R. E. Dixon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of Adeno-Associated Virus Serotypes and Delivery Methods for Cardiac Gene Transfer

(2012) Hongfei Fang et al.   Human Gene Therapy Methods

Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis

(2011) Brady K Atwood et al.   BMC GENOMICS

Restoration of Normal L-Type Ca 2+ Channel Function During Timothy Syndrome by Ablation of an Anchoring Protein

(2011) Edward P. Cheng et al.   CIRCULATION RESEARCH

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

β-Subunits Promote the Expression of CaV2.2 Channels by Reducing Their Proteasomal Degradation

(2011) Dominic Waithe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methods in cardiomyocyte isolation, culture, and gene transfer

(2011) William E. Louch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enhanced synaptic plasticity in mice with phosphomimetic mutation of the GluA1 AMPA receptor

(2011) Y. Makino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering biosynthetic excitable tissues from unexcitable cells for electrophysiological and cell therapy studies

(2011) Robert D. Kirkton et al.   Nature Communications

An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio

(2010) Yutaka Kodama* et al.   BIOTECHNIQUES

Increased Coupled Gating of L-Type Ca 2+ Channels During Hypertension and Timothy Syndrome

(2010) Manuel F. Navedo et al.   CIRCULATION RESEARCH

Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels

(2010) C. Blake Nichols et al.   CIRCULATION RESEARCH

The Cavβ subunit prevents RFP2-mediated ubiquitination and proteasomal degradation of L-type channels

(2010) Christophe Altier et al.   NATURE NEUROSCIENCE

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

Multiple levels of the single L-type Ca2+ channel conductance in adult mammalian ventricular myocytes

(2009) Ye Chen-Izu   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disruption of the IS6-AID Linker Affects Voltage-gated Calcium Channel Inactivation and Facilitation

(2009) Felix Findeisen et al.   JOURNAL OF GENERAL PHYSIOLOGY

Bimolecular Fluorescence Complementation Analysis of Inducible Protein Interactions: Effects of Factors Affecting Protein Folding on Fluorescent Protein Fragment Association

(2009) Aaron M. Robida et al.   JOURNAL OF MOLECULAR BIOLOGY

Gene Therapy in Heart Failure

(2008) Leif Erik Vinge et al.   CIRCULATION RESEARCH

Termination of Cardiac Ca 2+ Sparks

(2008) Aleksey V. Zima et al.   CIRCULATION RESEARCH

Unchanged β-Adrenergic Stimulation of Cardiac L-type Calcium Channels in Cav1.2 Phosphorylation Site S1928A Mutant Mice

(2008) Toni Lemke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Orientation of the Calcium Channel β Relative to the α12.2 Subunit Is Critical for Its Regulation of Channel Activity

(2008) Iuliia Vitko et al.   PLoS One

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling