Comparison of Adeno-Associated Virus Serotypes and Delivery Methods for Cardiac Gene Transfer

Gene Therapy for Heart Failure

(2012) Lisa Tilemann et al.   CIRCULATION RESEARCH

AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model

(2012) P. W. J. Raake et al.   EUROPEAN HEART JOURNAL

Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo

(2011) J D White et al.   GENE THERAPY

Improved Function of the Failing Rat Heart by Regulated Expression of Insulin-Like Growth Factor I via Intramuscular Gene Transfer

(2011) N. Chin Lai et al.   HUMAN GENE THERAPY

AAV Vectors for Cardiac Gene Transfer: Experimental Tools and Clinical Opportunities

(2011) Christina A Pacak et al.   MOLECULAR THERAPY

Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins

(2011) Amit C Nathwani et al.   MOLECULAR THERAPY

Cardiac AAV9-S100A1 Gene Therapy Rescues Post-Ischemic Heart Failure in a Preclinical Large Animal Model

(2011) S. T. Pleger et al.   Science Translational Medicine

Comparative Cardiac Gene Delivery of Adeno-Associated Virus Serotypes 1-9 reveals that AAV6 Mediates the Most Efficient Transduction in Mouse Heart

(2010) Carmela Zincarelli et al.   CTS-Clinical and Translational Science

Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution

(2010) K-M R Prasad et al.   GENE THERAPY

Current strategies for myocardial gene delivery

(2010) Michael G. Katz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice

(2010) Tong Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tailoring the AAV vector capsid for gene therapy

(2008) L H Vandenberghe et al.   GENE THERAPY

Percutaneous Transendocardial Delivery of Self-complementary Adeno-associated Virus 6 Achieves Global Cardiac Gene Transfer in Canines

(2008) Lawrence T Bish et al.   MOLECULAR THERAPY

Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

(2008) Carmela Zincarelli et al.   MOLECULAR THERAPY

Designing Heart Performance by Gene Transfer

(2008) Jennifer Davis et al.   PHYSIOLOGICAL REVIEWS