The protein arginine methyltransferase PRMT5 regulates Aβ-induced toxicity in human cells andCaenorhabditis elegansmodels of Alzheimer's disease

Asymmetric dimethylarginine exacerbates Aβ-induced toxicity and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease

(2015) Yunfeng Luo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma

(2014) Fengting Yan et al.   CANCER RESEARCH

Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro

(2014) Xiaosi Han et al.   JOURNAL OF NEURO-ONCOLOGY

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells

(2014) Ji Hyun Park et al.   Molecular Oncology

Association of cancer history with Alzheimer's disease onset and structural brain changes

(2014) Kelly N. H. Nudelman et al.   Frontiers in Physiology

Protein Arginine Methyltransferase 5 (PRMT5) Inhibition Induces Lymphoma Cell Death through Reactivation of the Retinoblastoma Tumor Suppressor Pathway and Polycomb Repressor Complex 2 (PRC2) Silencing

(2013) Jihyun Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PRMT5 dimethylates R30 of the p65 subunit to activate NF- B

(2013) H. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginine methylation controls growth regulation by E2F-1

(2012) Er-Chieh Cho et al.   EMBO JOURNAL

Protein Arginine Methyltransferase 5 Accelerates Tumor Growth by Arginine Methylation of the Tumor Suppressor Programmed Cell Death 4

(2011) M. A. Powers et al.   CANCER RESEARCH

Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans

(2011) Roongpetch Keowkase et al.   Molecular Neurodegeneration

Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease

(2011) B. DaRocha-Souto et al.   NEUROBIOLOGY OF DISEASE

Copper ions influence the toxicity of β-amyloid(1–42) in a concentration-dependent manner in a Caenorhabditis elegans model of Alzheimer’s disease

(2011) YunFeng Luo et al.   Science China-Life Sciences

Versatility of PRMT5-induced methylation in growth control and development

(2011) Vrajesh Karkhanis et al.   TRENDS IN BIOCHEMICAL SCIENCES

β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease

(2010) Li Wan et al.   FREE RADICAL BIOLOGY AND MEDICINE

The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans

(2009) S. S. Wolf   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Evidence of molecular links between PKR and mTOR signalling pathways in Aβ neurotoxicity: Role of p53, Redd1 and TSC2

(2009) Milena Morel et al.   NEUROBIOLOGY OF DISEASE

PRMT5 is required for cell-cycle progression and p53 tumor suppressor function

(2009) A. Scoumanne et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis

(2009) Mei Yang et al.   PLoS Genetics

Protein Arginine Methyltransferase 5 Suppresses the Transcription of the RB Family of Tumor Suppressors in Leukemia and Lymphoma Cells

(2008) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Arginine methylation regulates the p53 response

(2008) Martin Jansson et al.   NATURE CELL BIOLOGY