Glycerol kinase 5 confers gefitinib resistance through SREBP1/SCD1 signaling pathway

PLAUR Confers Resistance to Gefitinib Through EGFR/P-AKT/Survivin Signaling Pathway

(2018) Jian Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells

(2018) Guanghua Liu et al.   ONCOGENE

Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer

(2018) Yang-An Wen et al.   Cell Death & Disease

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

(2017) Jiqin Zhang et al.   Molecular Cancer

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

(2017) A Noto et al.   ONCOGENE

Treatments for EGFR-mutant non-small cell lung cancer (NSCLC): The road to a success, paved with failures

(2017) Dae Ho Lee   PHARMACOLOGY & THERAPEUTICS

Extracellular mRNA Detected by Tethered Lipoplex Nanoparticle Biochip for Lung Adenocarcinoma Detection

(2016) L. James Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SREBP-1 is an independent prognostic marker and promotes invasion and migration in breast cancer

(2016) Jisheng Bao et al.   Oncology Letters

A Kinase-Independent Role for EGF Receptor in Autophagy Initiation

(2015) Xiaojun Tan et al.   CELL

Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer

(2015) Chee-Seng Tan et al.   LANCET ONCOLOGY

Mechanisms of resistance to EGFR tyrosine kinase inhibitors

(2015) Lihua Huang et al.   Acta Pharmaceutica Sinica B

Detection of Extracellular RNAs in Cancer and Viral Infection via Tethered Cationic Lipoplex Nanoparticles Containing Molecular Beacons

(2013) Yun Wu et al.   ANALYTICAL CHEMISTRY

The quest to overcome resistance to EGFR-targeted therapies in cancer

(2013) Curtis R Chong et al.   NATURE MEDICINE

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

(2013) A Noto et al.   Cell Death & Disease

Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab

(2012) Gang Chen et al.   BMC Medicine

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

(2012) Rafael Rosell et al.   LANCET ONCOLOGY

EGFR-mediated stimulation of sodium/glucose cotransport promotes survival of irradiated human A549 lung adenocarcinoma cells

(2012) Stephan M. Huber et al.   RADIOTHERAPY AND ONCOLOGY

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells

(2011) W.-C. Huang et al.   MOLECULAR CANCER RESEARCH

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptomic and network component analysis of glycerol kinase in skeletal muscle using a mouse model of glycerol kinase deficiency

(2009) Lola Rahib et al.   MOLECULAR GENETICS AND METABOLISM

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy

(2009) D. Guo et al.   Science Signaling

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL