EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

(2015) Guang-Ming Huang et al.   CANCER LETTERS

EGFR Modulates DNA Synthesis and Repair through Tyr Phosphorylation of Histone H4

(2014) Ruey-Hwang Chou et al.   DEVELOPMENTAL CELL

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis

(2014) Haizhong Feng et al.   JOURNAL OF CLINICAL INVESTIGATION

Network Meta-Analysis of Erlotinib, Gefitinib, Afatinib and Icotinib in Patients with Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations

(2014) Wenhua Liang et al.   PLoS One

Epidermal Growth Factor Receptor Potentiates MCM7-Mediated DNA Replication through Tyrosine Phosphorylation of Lyn Kinase in Human Cancers

(2013) Tzu-Hsuan Huang et al.   CANCER CELL

EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

(2013) Yongjie Wei et al.   CELL

EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2

(2013) Jia Shen et al.   NATURE

Human Breast Cancer Tissues Contain Abundant Phosphatidylcholine(36∶1) with High Stearoyl-CoA Desaturase-1 Expression

(2013) Yoshimi Ide et al.   PLoS One

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

(2013) A Noto et al.   Cell Death & Disease

High stearoyl-CoA desaturase 1 expression is associated with shorter survival in breast cancer patients

(2012) Ashley M. Holder et al.   BREAST CANCER RESEARCH AND TREATMENT

Lipid metabolism in cancer

(2012) Claudio R. Santos et al.   FEBS Journal

Cancer Cell Metabolism: One Hallmark, Many Faces

(2012) Jason R. Cantor et al.   Cancer Discovery

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy

(2011) U. V. Roongta et al.   MOLECULAR CANCER RESEARCH

Roles of StearoylCoA Desaturase-1 in the Regulation of Cancer Cell Growth, Survival and Tumorigenesis

(2011) R. Ariel Igal   Cancers

Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

(2010) R. A. Igal   CARCINOGENESIS

Rapamycin Regulates Stearoyl CoA Desaturase 1 Expression in Breast Cancer

(2010) D. Luyimbazi et al.   MOLECULAR CANCER THERAPEUTICS

Abrogation of De novo Lipogenesis by Stearoyl-CoA Desaturase 1 Inhibition Interferes with Oncogenic Signaling and Blocks Prostate Cancer Progression in Mice

(2010) V. Fritz et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

(2010) Daniel Hess et al.   PLoS One

Inhibition of Stearoyl-CoA Desaturase 1 Expression Induces CHOP-Dependent Cell Death in Human Cancer Cells

(2010) Mélaine Minville-Walz et al.   PLoS One

Inhibition of StearoylCoA Desaturase-1 Inactivates Acetyl-CoA Carboxylase and Impairs Proliferation in Cancer Cells: Role of AMPK

(2009) Natalia Scaglia et al.   PLoS One

Biochemical and physiological function of stearoyl-CoA desaturase

(2008) Chad M. Paton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL