Mesenchymal Cell-Derived Juxtacrine Wnt1 Signaling Regulates Osteoblast Activity and Osteoclast Differentiation

Differences in the secretion and transport of Wnt proteins

(2017) Shinji Takada et al.   JOURNAL OF BIOCHEMISTRY

Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis

(2017) Kyu Sang Joeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Heparan Sulfate Regulates the Structure and Function of Osteoprotegerin in Osteoclastogenesis

(2016) Miaomiao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

(2016) Henner F. Farin et al.   NATURE

Cortical-Bone Fragility — Insights from sFRP4 Deficiency in Pyle’s Disease

(2016) Pelin O. Simsek Kiper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Romosozumab Treatment in Postmenopausal Women with Osteoporosis

(2016) Felicia Cosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wnt16 regulates osteoclast differentiation in conjunction with Wnt5a

(2015) Yasuhiro Kobayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

KN-93 inhibits IKr in mammalian cardiomyocytes

(2015) Bence Hegyi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The swaying mouse as a model of osteogenesis imperfecta caused by WNT1 mutations

(2014) Kyu Sang Joeng et al.   HUMAN MOLECULAR GENETICS

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

(2014) Sofia Movérare-Skrtic et al.   NATURE MEDICINE

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

WNT1 Mutations in Families Affected by Moderately Severe and Progressive Recessive Osteogenesis Imperfecta

(2013) Shawna M. Pyott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in WNT1 Cause Different Forms of Bone Fragility

(2013) Katharina Keupp et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mutations in WNT1 are a cause of osteogenesis imperfecta

(2013) Somayyeh Fahiminiya et al.   JOURNAL OF MEDICAL GENETICS

Patterning and growth control by membrane-tethered Wingless

(2013) Cyrille Alexandre et al.   NATURE

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

WNT1 Mutations in Early-Onset Osteoporosis and Osteogenesis Imperfecta

(2013) Christine M. Laine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rare variations in WNT3A and DKK1 may predispose carriers to primary osteoporosis

(2012) Johanna Korvala et al.   European Journal of Medical Genetics

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

Wntless functions in mature osteoblasts to regulate bone mass

(2012) Z. Zhong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk

(2012) Hou-Feng Zheng et al.   PLoS Genetics

Update on Wnt signaling in bone cell biology and bone disease

(2011) David G. Monroe et al.   GENE

Cardiac Induction of Embryonic Stem Cells by a Small Molecule Inhibitor of Wnt/β-Catenin Signaling

(2010) Hanmin Wang et al.   ACS Chemical Biology

The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators

(2010) Jia-Ling Teo et al.   ADVANCED DRUG DELIVERY REVIEWS

Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations

(2010) Ce Liu et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Osteocyte Wnt/ -Catenin Signaling Is Required for Normal Bone Homeostasis

(2010) I. Kramer et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

(2010) S. A. Ettenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation

(2009) Takako Negishi-Koga et al.   IMMUNOLOGICAL REVIEWS