Cardiac phenotype in mouse models of systemic autoimmunity

Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients

(2018) Cristina M. Lanata et al.   PLoS One

Longitudinal Stratification of Gene Expression Reveals Three SLE Groups of Disease Activity Progression

(2018) Daniel Toro-Domínguez et al.   Arthritis & Rheumatology

rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling

(2018) Anandharajan Rathinasabapathy et al.   Frontiers in Physiology

Living inside the box: environmental effects on mouse models of human disease

(2018) John P. Sundberg et al.   Disease Models & Mechanisms

Systemic sclerosis

(2017) Christopher P Denton et al.   LANCET

Novel risk genes for systemic lupus erythematosus predicted by random forest classification

(2017) Jonas Carlsson Almlöf et al.   Scientific Reports

Control of lupus nephritis by changes of gut microbiota

(2017) Qinghui Mu et al.   Microbiome

Reactive Oxygen Species Regulate Innate But Not Adaptive Inflammation in ZAP70-Mutated SKG Arthritic Mice

(2016) Simon Guerard et al.   AMERICAN JOURNAL OF PATHOLOGY

Cardiovascular disease in inflammatory rheumatic diseases

(2016) Santos Castañeda et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

The establishment of a porcine rheumatoid arthritis model: Collagen induced arthritis minipig model

(2016) Won Jae Lee et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Lupus Myocarditis: Initial Presentation and Longterm Outcomes in a Multicentric Series of 29 Patients

(2016) Guillemette Thomas et al.   JOURNAL OF RHEUMATOLOGY

Modelling clinical systemic lupus erythematosus: similarities, differences and success stories

(2016) Teja Celhar et al.   RHEUMATOLOGY

The SKG Mutation in ZAP-70 also Confers Arthritis Susceptibility in C57 Black Mouse Strains

(2016) S. Guerard et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Systemic lupus erythematosus

(2016) Arvind Kaul et al.   Nature Reviews Disease Primers

A comparison of human and mouse gene co-expression networks reveals conservation and divergence at the tissue, pathway and disease levels

(2015) Gianni Monaco et al.   BMC EVOLUTIONARY BIOLOGY

Collagen-induced arthritis increases inducible nitric oxide synthase not only in aorta but also in the cardiac and renal microcirculation of mice

(2015) G. Palma Zochio Tozzato et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1mice

(2015) B. M. Johnson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Spontaneous retrotransposon insertion intoTNF3′UTR causes heart valve disease and chronic polyarthritis

(2015) Derek Lacey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting of type I interferon in systemic autoimmune diseases

(2015) Mary K. Crow et al.   Translational Research

Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus

(2015) Agostino Virdis et al.   ARTHRITIS RESEARCH & THERAPY

Cardiomyopathy in Murine Models of Systemic Sclerosis

(2015) Paulius Venalis et al.   Arthritis & Rheumatology

Mechanisms of Autoantibody Production in Systemic Lupus Erythematosus

(2015) Shuhong Han et al.   Frontiers in Immunology

Systemic sclerosis

(2015) Yannick Allanore et al.   Nature Reviews Disease Primers

Chronic Hydroxychloroquine Improves Endothelial Dysfunction and Protects Kidney in a Mouse Model of Systemic Lupus Erythematosus

(2014) Manuel Gómez-Guzmán et al.   HYPERTENSION

CD4+ T Cells Recognizing a Single Self-Peptide Expressed by APCs Induce Spontaneous Autoimmune Arthritis

(2014) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Programmed Death Ligand 1 Regulates a Critical Checkpoint for Autoimmune Myocarditis and Pneumonitis in MRL Mice

(2014) J. A. Lucas et al.   JOURNAL OF IMMUNOLOGY

Systemic lupus erythematosus

(2014) Larissa Lisnevskaia et al.   LANCET

Tight skin 2 mice exhibit a novel time line of events leading to increased extracellular matrix deposition and dermal fibrosis

(2014) Kristen B. Long et al.   MATRIX BIOLOGY

ZAP-70 Genotype Disrupts the Relationship Between Microbiota and Host, Leading to Spondyloarthritis and Ileitis in SKG Mice

(2014) Linda M. Rehaume et al.   Arthritis & Rheumatology

Systematic Review: Accuracy of Anti–Citrullinated Peptide Antibodies for Diagnosing Rheumatoid Arthritis

(2013) Penny F. Whiting   ANNALS OF INTERNAL MEDICINE

Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?

(2013) Mirko Manetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Endothelial Dysfunction in Rheumatoid Arthritis

(2013) Ming He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autoimmune diseases, their pharmacological treatment and the cardiovascular system

(2013) Marta Jastrzębska et al.   Cardiology Journal

The epidemiology of atherosclerotic cardiovascular disease among patients with SLE: A systematic review

(2013) Sara R. Schoenfeld et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Pathophysiological role of neutrophils in acute myocardial infarction

(2013) Federico Carbone et al.   THROMBOSIS AND HAEMOSTASIS

Epicutaneous Application of Toll-like Receptor 7 Agonists Leads to Systemic Autoimmunity in Wild-Type Mice: A New Model of Systemic Lupus Erythematosus

(2013) Maki Yokogawa et al.   Arthritis & Rheumatology

Fcγ Receptor III and Fcγ Receptor IV on Macrophages Drive Autoimmune Valvular Carditis in Mice

(2013) Patricia M. Hobday et al.   Arthritis & Rheumatology

Contractile, but not endothelial, dysfunction in early inflammatory arthritis: a possible role for matrix metalloproteinase-9

(2012) SL Reynolds et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tumor Necrosis Factor-α Signaling in Macrophages

(2012) Narayanan Parameswaran et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

A model 450 million years in the making: zebrafish and vertebrate immunity

(2012) S. A. Renshaw et al.   Disease Models & Mechanisms

The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population

(2012)   GENETICS

Degradation of Internalized αvβ5 Integrin Is Controlled by uPAR Bound uPA: Effect on β1 Integrin Activity and α-SMA Stress Fiber Assembly

(2012) Lingyan Wang et al.   PLoS One

4F Decreases IRF5 Expression and Activation in Hearts of Tight Skin Mice

(2012) Hao Xu et al.   PLoS One

The Fra-2 transgenic mouse model of systemic sclerosis

(2012) Britta Maurer et al.   VASCULAR PHARMACOLOGY

Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study

(2012) Jon T Giles et al.   ARTHRITIS RESEARCH & THERAPY

Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis

(2012) Lukasz Stawski et al.   ARTHRITIS RESEARCH & THERAPY

Immunization with DNA topoisomerase I and Freund's complete adjuvant induces skin and lung fibrosis and autoimmunity via interleukin-6 signaling

(2011) Ayumi Yoshizaki et al.   ARTHRITIS AND RHEUMATISM

Murine Models of Systemic Lupus Erythematosus

(2011) Daniel Perry et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Characterization of a novel and spontaneous mouse model of inflammatory arthritis

(2011) Iris A Adipue et al.   ARTHRITIS RESEARCH & THERAPY

Correction: Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

(2011) Matteo Fumagalli et al.   PLoS Genetics

Left-Sided Cardiac Valvulitis in Tristetraprolin-Deficient Mice

(2010) Sanjukta Ghosh et al.   AMERICAN JOURNAL OF PATHOLOGY

Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis

(2010) Hao Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Animal models of systemic sclerosis: Prospects and limitations

(2010) Christian Beyer et al.   ARTHRITIS AND RHEUMATISM

Nucleic acid sensing Toll-like receptors in autoimmunity

(2010) Sarah E Ewald et al.   CURRENT OPINION IN IMMUNOLOGY

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

(2010) Jian Wang et al.   INTERNATIONAL IMMUNOLOGY

Advances in lupus stemming from the parent-into-F1 model

(2010) Charles S. Via   TRENDS IN IMMUNOLOGY

Atherosclerotic vascular events in a multinational inception cohort of systemic lupus erythematosus

(2010) M. B. Urowitz et al.   ARTHRITIS CARE & RESEARCH

Animal models of rheumatoid arthritis

(2009) Darren L. Asquith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cardiac pathology of systemic lupus erythematosus

(2009) D Jain et al.   JOURNAL OF CLINICAL PATHOLOGY

Induction of Autoimmunity in a Bleomycin-Induced Murine Model of Experimental Systemic Sclerosis: An Important Role for CD4+ T Cells

(2009) Hideaki Ishikawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The same systemic autoimmune disease provokes arthritis and endocarditis via distinct mechanisms

(2009) B. A. Binstadt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predictors of cardiovascular damage in patients with systemic lupus erythematosus: data from LUMINA (LXVIII), a multiethnic US cohort

(2009) G. J. Pons-Estel et al.   RHEUMATOLOGY

Risk of cardiovascular mortality in patients with rheumatoid arthritis: A meta-analysis of observational studies

(2008) J. Antonio Aviña-Zubieta et al.   ARTHRITIS AND RHEUMATISM

Inducible nitric oxide synthase activity is increased in patients with rheumatoid arthritis and contributes to endothelial dysfunction

(2008) Kaisa M. Mäki-Petäjä et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Absence of uPAR Is Associated with the Progression of Dermal Fibrosis

(2008) Yosuke Kanno et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1

(2008) R. Eferl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Heart in Scleroderma

(2008) Hunter C. Champion   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Macrovascular disease in systemic sclerosis: the tip of an iceberg?

(2008) J. J. F. Belch et al.   RHEUMATOLOGY

Pro- and anti-fibrotic effects of TGF-  in scleroderma

(2008) R. Sgonc et al.   RHEUMATOLOGY

Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

(2008) Antonio Naranjo et al.   ARTHRITIS RESEARCH & THERAPY

PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation

(2007) Anna R. Hemnes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY