Cardiomyopathy in Murine Models of Systemic Sclerosis

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis

(2013) Michal Tomcik et al.   ANNALS OF THE RHEUMATIC DISEASES

Activation of pregnane X receptor inhibits experimental dermal fibrosis

(2013) Christian Beyer et al.   ANNALS OF THE RHEUMATIC DISEASES

Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?

(2013) Mirko Manetti et al.   ANNALS OF THE RHEUMATIC DISEASES

Combined Inhibition of c-Abl and PDGF Receptors for Prevention and Treatment of Murine Sclerodermatous Chronic Graft-versus-Host Disease

(2012) Pawel Zerr et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of sumoylation prevents experimental fibrosis

(2012) Aisa Khodzhigorova et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of hedgehog signalling prevents experimental fibrosis and induces regression of established fibrosis

(2012) Angelika Horn et al.   ANNALS OF THE RHEUMATIC DISEASES

The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis

(2012) Gerhard Krönke et al.   ANNALS OF THE RHEUMATIC DISEASES

Jun N-terminal kinase as a potential molecular target for prevention and treatment of dermal fibrosis

(2012) Nicole Reich et al.   ANNALS OF THE RHEUMATIC DISEASES

Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1

(2012) Katrin Palumbo-Zerr et al.   ANNALS OF THE RHEUMATIC DISEASES

Prevalence of coronary heart disease and cardiovascular risk factors in a national cross-sectional cohort study of systemic sclerosis

(2012) Gene-Siew Ngian et al.   ANNALS OF THE RHEUMATIC DISEASES

Pomalidomide is effective for prevention and treatment of experimental skin fibrosis

(2012) Simon Weingärtner et al.   ANNALS OF THE RHEUMATIC DISEASES

Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis

(2012) Britta Maurer et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of H3K27 histone trimethylation activates fibroblasts and induces fibrosis

(2012) Marlene Krämer et al.   ANNALS OF THE RHEUMATIC DISEASES

JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis

(2012) Clara Dees et al.   ARTHRITIS AND RHEUMATISM

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease

(2012) P. Zerr et al.   BLOOD

4F Decreases IRF5 Expression and Activation in Hearts of Tight Skin Mice

(2012) Hao Xu et al.   PLoS One

The Fra-2 transgenic mouse model of systemic sclerosis

(2012) Britta Maurer et al.   VASCULAR PHARMACOLOGY

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

The transcription factor JunD mediates transforming growth factor  -induced fibroblast activation and fibrosis in systemic sclerosis

(2011) K. Palumbo et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis

(2011) Clara Dees et al.   ARTHRITIS AND RHEUMATISM

Systemic sclerosis and the heart

(2011) Chintan S. Desai et al.   CURRENT OPINION IN RHEUMATOLOGY

Platelet-derived serotonin links vascular disease and tissue fibrosis

(2011) Clara Dees et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies

(2011) M. Elhai et al.   RHEUMATOLOGY

Endothelial Fli1 Deficiency Impairs Vascular Homeostasis

(2010) Yoshihide Asano et al.   AMERICAN JOURNAL OF PATHOLOGY

Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database

(2010) A. J. Tyndall et al.   ANNALS OF THE RHEUMATIC DISEASES

Animal models of systemic sclerosis: Prospects and limitations

(2010) Christian Beyer et al.   ARTHRITIS AND RHEUMATISM

Decreased lymphatic vessel counts in patients with systemic sclerosis: Association with fingertip ulcers

(2010) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma

(2010) Emma C Derrett-Smith et al.   ARTHRITIS RESEARCH & THERAPY

Heart involvement in systemic sclerosis: Evolving concept and diagnostic methodologies

(2009) Christophe Meune et al.   Archives of Cardiovascular Diseases

Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis

(2009) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis

(2009) Nicole Reich et al.   ARTHRITIS AND RHEUMATISM

Transcription Factor Fos-Related Antigen-2 Induces Progressive Peripheral Vasculopathy in Mice Closely Resembling Human Systemic Sclerosis

(2009) Britta Maurer et al.   CIRCULATION

Cardiac magnetic resonance imaging in systemic sclerosis: a cross-sectional observational study of 52 patients

(2008) A-L Hachulla et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1

(2008) R. Eferl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myocardial involvement in systemic sclerosis

(2008) L. Belloli et al.   RHEUMATOLOGY

Outcome measures for heart involvement in systemic sclerosis

(2008) Y. Allanore et al.   RHEUMATOLOGY