The molecular neurobiology of chronic pain–induced depression

Endometriosis alters brain electrophysiology, gene expression and increases pain sensitization, anxiety, and depression in female mice†

(2018) Tian Li et al.   BIOLOGY OF REPRODUCTION

Hyperactivity of Anterior Cingulate Cortex Areas 24a/24b Drives Chronic Pain-Induced Anxiodepressive-like Consequences

(2018) Jim Sellmeijer et al.   JOURNAL OF NEUROSCIENCE

Genetic and environmental influences to low back pain and symptoms of depression and anxiety: A population-based twin study

(2018) Marina B. Pinheiro et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

The role of hippocampal brain-derived neurotrophic factor in age-related differences in neuropathic pain behavior in rats

(2018) Hiroki Tateiwa et al.   LIFE SCIENCES

Ketamine differentially restores diverse alterations of neuroligins in brain regions in a rat model of neuropathic pain-induced depression

(2018) Wei Pan et al.   NEUROREPORT

Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain

(2018) Xi Jiang et al.   NEUROSCIENCE LETTERS

Brain-derived neurotrophic factor–mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry

(2018) Di Liu et al.   PAIN

Inflammatory and neuropathic pain conditions do not primarily evoke anxiety-like behaviours in C57BL/6 mice

(2018) Claudia Pitzer et al.   EUROPEAN JOURNAL OF PAIN

Depression and anxiety behaviour in a rat model of chronic migraine

(2017) Mingjie Zhang et al.   JOURNAL OF HEADACHE AND PAIN

Adult Hippocampal Neurogenesis along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice

(2017) Jie Zheng et al.   JOURNAL OF NEUROSCIENCE

New roles for neuronal estrogen receptors

(2017) C.-L. Lu et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Genetic and Environmental Influences on Sleep, Pain, and Depression Symptoms in a Community Sample of Twins

(2017) Marianna Gasperi et al.   PSYCHOSOMATIC MEDICINE

Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression

(2017) Giannina Descalzi et al.   Science Signaling

Impaired Spinal Glucocorticoid Receptor Signaling Contributes to the Attenuating Effect of Depression on Mechanical Allodynia and Thermal Hyperalgesia in Rats with Neuropathic Pain

(2017) Xiao Wei et al.   Frontiers in Cellular Neuroscience

Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression

(2017) Giannina Descalzi et al.   Science Signaling

Chronic pain and adult hippocampal neurogenesis: translational implications from preclinical studies

(2017) Mariagrazia Grilli   Journal of Pain Research

Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine

(2017) Ze-Min Xie et al.   Scientific Reports

Evidence that CA3 is Underling the Comorbidity Between Pain and Depression and the Co-curation by Wu-Tou decoction in Neuropathic Pain

(2017) Chunyan Zhu et al.   Scientific Reports

Upregulation of prefrontal metabotropic glutamate receptor 5 mediates neuropathic pain and negative mood symptoms after spinal nerve injury in rats

(2017) Geehoon Chung et al.   Scientific Reports

Brain-derived neurotrophic factor (BDNF) in the rostral anterior cingulate cortex (rACC) contributes to neuropathic spontaneous pain-related aversion via NR2B receptors

(2016) Le Zhang et al.   BRAIN RESEARCH BULLETIN

Effects of pregabalin on the nociceptive, emotional and cognitive manifestations of neuropathic pain in mice

(2016) C. La Porta et al.   EUROPEAN JOURNAL OF PAIN

Why depression and pain often coexist and mutually reinforce: Role of the lateral habenula

(2016) Jicheng Li et al.   EXPERIMENTAL NEUROLOGY

Ketamine: NMDA Receptors and Beyond

(2016) C. F. Zorumski et al.   JOURNAL OF NEUROSCIENCE

Plant Natural Product Puerarin Ameliorates Depressive Behaviors and Chronic Pain in Mice with Spared Nerve Injury (SNI)

(2016) Jia Zhao et al.   MOLECULAR NEUROBIOLOGY

Circulating microRNA Profiles as Liquid Biopsies for the Characterization and Diagnosis of Fibromyalgia Syndrome

(2016) Andrea Masotti et al.   MOLECULAR NEUROBIOLOGY

Cingulate GABA levels inversely correlate with the intensity of ongoing chronic knee osteoarthritis pain

(2016) Diane Reckziegel et al.   Molecular Pain

Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

(2016) Wen-Shan Gui et al.   Molecular Pain

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4

(2016) C Zussy et al.   MOLECULAR PSYCHIATRY

Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model

(2016) Guang-Fen Zhang et al.   NEUROSCIENCE LETTERS

Pain relief induces dopamine release in the rat nucleus accumbens during the early but not late phase of neuropathic pain

(2016) Takahiro Kato et al.   NEUROSCIENCE LETTERS

Comorbid anxiety-like behavior and locus coeruleus impairment in diabetic peripheral neuropathy: A comparative study with the chronic constriction injury model

(2016) Cristina Alba-Delgado et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Association of pain intensity, pain-related disability, and depression with hypothalamus–pituitary–adrenal axis function in female patients with chronic temporomandibular disorders

(2016) Kyung B. Jo et al.   PSYCHONEUROENDOCRINOLOGY

Neural Mechanisms Underlying Anxiety–Chronic Pain Interactions

(2016) Min Zhuo   TRENDS IN NEUROSCIENCES

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis

(2016) Andrew M. McIntosh et al.   PLOS MEDICINE

The role of inflammatory cytokines and ERK1/2 signaling in chronic prostatitis/chronic pelvic pain syndrome with related mental health disorders

(2016) Chao Hu et al.   Scientific Reports

Stress Increases the Negative Effects of Chronic Pain on Hippocampal Neurogenesis

(2015) Carmen Romero-Grimaldi et al.   ANESTHESIA AND ANALGESIA

Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype

(2015) Nikita N. Burke et al.   BEHAVIOURAL BRAIN RESEARCH

Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice

(2015) Wenjun Zhou et al.   BRAIN BEHAVIOR AND IMMUNITY

Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain

(2015) G. Hache et al.   EUROPEAN JOURNAL OF PAIN

Respective pharmacological features of neuropathic-like pain evoked by intrathecal BDNF versus sciatic nerve ligation in rats

(2015) Saïd M’Dahoma et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Chronic pain causes a persistent anxiety state leading to increased ethanol intake in CD1 mice

(2015) Marta González-Sepúlveda et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Coexistence of Two Forms of LTP in ACC Provides a Synaptic Mechanism for the Interactions between Anxiety and Chronic Pain

(2015) Kohei Koga et al.   NEURON

Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain

(2015) Claudia Sagheddu et al.   NEUROPHARMACOLOGY

Thalidomide reduces mechanical hyperalgesia and depressive-like behavior induced by peripheral nerve crush in mice

(2015) F.P. Nascimento et al.   NEUROSCIENCE

Genetics and the environment affect the relationship between depression and low back pain

(2015) Marina B. Pinheiro et al.   PAIN

Role of the endocannabinoid system in the emotional manifestations of osteoarthritis pain

(2015) Carmen La Porta et al.   PAIN

Exercise therapy normalizes BDNF upregulation and glial hyperactivity in a mouse model of neuropathic pain

(2015) Cayo Almeida et al.   PAIN

Integrating the monoamine, neurotrophin and cytokine hypotheses of depression — A central role for the serotonin transporter?

(2015) Jana Haase et al.   PHARMACOLOGY & THERAPEUTICS

The Association between Chronic Widespread Musculoskeletal Pain, Depression and Fatigue Is Genetically Mediated

(2015) Andrea Burri et al.   PLoS One

m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model

(2015) César Augusto Brüning et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Epigenetic mechanisms of chronic pain

(2015) Giannina Descalzi et al.   TRENDS IN NEUROSCIENCES

Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety

(2015) Guo-Qiang Wang et al.   Nature Communications

Role of Prelimbic GABAergic Circuits in Sensory and Emotional Aspects of Neuropathic Pain

(2015) Zizhen Zhang et al.   Cell Reports

Persistent pain alters AMPA receptor subunit levels in the nucleus accumbens

(2015) Chen Su et al.   Molecular Brain

AMPAkines Have Novel Analgesic Properties in Rat Models of Persistent Neuropathic and Inflammatory Pain

(2014) Alexander M. Le et al.   ANESTHESIOLOGY

Interaction between stress and the BDNFVal66Met polymorphism in depression: a systematic review and meta-analysis

(2014) Georgina M Hosang et al.   BMC Medicine

Reduced hypothalamic-pituitary-adrenal axis activity in chronic multi-site musculoskeletal pain: partly masked by depressive and anxiety disorders

(2014) Ellen Generaal et al.   BMC MUSCULOSKELETAL DISORDERS

Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling

(2014) Anna Dellarole et al.   BRAIN BEHAVIOR AND IMMUNITY

Imipramine Ameliorates Pain-related Negative Emotion via Induction of Brain-derived Neurotrophic Factor

(2014) Seiko Yasuda et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Oral 2-hydroxyoleic acid inhibits reflex hypersensitivity and open-field-induced anxiety after spared nerve injury

(2014) G. Avila-Martin et al.   EUROPEAN JOURNAL OF PAIN

Pain exacerbates chronic mild stress-induced changes in noradrenergic transmission in rats

(2014) Lidia Bravo et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Anxiety- and Depression-Like Behavior and Impaired Neurogenesis Evoked by Peripheral Neuropathy Persist following Resolution of Prolonged Tactile Hypersensitivity

(2014) E. L. Dimitrov et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Injury Causes Brain Inflammation Associated with Cognitive and Affective Changes: Role of Cell Cycle Pathways

(2014) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics

(2014) Natalie Matosin et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Why are cortical GABA neurons relevant to internal focus in depression? A cross-level model linking cellular, biochemical and neural network findings

(2014) G Northoff et al.   MOLECULAR PSYCHIATRY

Epigenetic modulation of chronic anxiety and pain by histone deacetylation

(2014) L Tran et al.   MOLECULAR PSYCHIATRY

Attenuation of Reserpine-Induced Pain/Depression Dyad by Gentiopicroside Through Downregulation of GluN2B Receptors in the Amygdala of Mice

(2014) Shui-bing Liu et al.   NEUROMOLECULAR MEDICINE

Depression-related behavior and mechanical allodynia are blocked by 3-(4-fluorophenylselenyl)-2,5-diphenylselenophene in a mouse model of neuropathic pain induced by partial sciatic nerve ligation

(2014) Bibiana Mozzaquatro Gai et al.   NEUROPHARMACOLOGY

Chronic resveratrol treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with mononeuropathy: Involvement of serotonergic system

(2014) Xin Zhao et al.   NEUROPHARMACOLOGY

Therapeutic Potential of Inhibitors of Endocannabinoid Degradation for the Treatment of Stress-Related Hyperalgesia in an Animal Model of Chronic Pain

(2014) Ermelinda Lomazzo et al.   NEUROPSYCHOPHARMACOLOGY

4-Methylcatechol prevents derangements of brain-derived neurotrophic factor and TrkB-related signaling in anterior cingulate cortex in chronic pain with depression-like behavior

(2014) Kozo Ishikawa et al.   NEUROREPORT

Emotional consequences of neuropathic pain: Insight from preclinical studies

(2014) Ipek Yalcin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Activation of mesocorticolimbic reward circuits for assessment of relief of ongoing pain: A potential biomarker of efficacy

(2014) Jennifer Y. Xie et al.   PAIN

Suppression of bone marrow–derived microglia in the amygdala improves anxiety-like behavior induced by chronic partial sciatic nerve ligation in mice

(2014) Atsushi Sawada et al.   PAIN

Oral administration of the p38α MAPK inhibitor, UR13870, inhibits affective pain behavior after spinal cord injury

(2014) Iriana Galan-Arriero et al.   PAIN

Tramadol reduces anxiety-related and depression-associated behaviors presumably induced by pain in the chronic constriction injury model of neuropathic pain in rats

(2014) Ombretta Caspani et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Preclinical research on pain comorbidity with affective disorders and cognitive deficits: Challenges and perspectives

(2014) Ming-Gang Liu et al.   PROGRESS IN NEUROBIOLOGY

Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

(2014) Ming-Ming Zhang et al.   Molecular Brain

An altered spinal serotonergic system contributes to increased thermal nociception in an animal model of depression

(2014) Antonio Rodríguez-Gaztelumendi et al.   EXPERIMENTAL BRAIN RESEARCH

Possible involvement of oxido-nitrosative stress induced neuro-inflammatory cascade and monoaminergic pathway: Underpinning the correlation between nociceptive and depressive behaviour in a rodent model

(2013) Vipin Arora et al.   JOURNAL OF AFFECTIVE DISORDERS

Calcium-Permeable AMPA Receptors in the Nucleus Accumbens Regulate Depression-Like Behaviors in the Chronic Neuropathic Pain State

(2013) Y. Goffer et al.   JOURNAL OF NEUROSCIENCE

Maternal Deprivation Is Associated With Sex-Dependent Alterations in Nociceptive Behavior and Neuroinflammatory Mediators in the Rat Following Peripheral Nerve Injury

(2013) Nikita N. Burke et al.   JOURNAL OF PAIN

Ferulic acid increases pain threshold and ameliorates depression-like behaviors in reserpine-treated mice: behavioral and neurobiological analyses

(2013) Ying Xu et al.   METABOLIC BRAIN DISEASE

Pathophysiology of somatosensory abnormalities in Parkinson disease

(2013) Antonella Conte et al.   Nature Reviews Neurology

Social stress exacerbates the aversion to painful experiences in rats exposed to chronic pain: The role of the locus coeruleus

(2013) Lidia Bravo et al.   PAIN

Synergistic Effects of Celecoxib and Bupropion in a Model of Chronic Inflammation-Related Depression in Mice

(2013) Izaque S. Maciel et al.   PLoS One

Regulator of G protein signaling 4 is a crucial modulator of antidepressant drug action in depression and neuropathic pain models

(2013) M. Stratinaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

(2013) C. Nasca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic curcumin treatment normalizes depression-like behaviors in mice with mononeuropathy: involvement of supraspinal serotonergic system and GABAA receptor

(2013) Xin Zhao et al.   PSYCHOPHARMACOLOGY

Symptom clusters of pain, depressed mood, and fatigue in lung cancer: assessing the role of cytokine genes

(2013) Cielito C. Reyes-Gibby et al.   SUPPORTIVE CARE IN CANCER

Chronic Pain Leads to Concomitant Noradrenergic Impairment and Mood Disorders

(2012) Cristina Alba-Delgado et al.   BIOLOGICAL PSYCHIATRY

Operant self-administration of a sigma ligand improves nociceptive and emotional manifestations of neuropathic pain

(2012) A.S. Bura et al.   EUROPEAN JOURNAL OF PAIN

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

(2012) Hyangin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Abnormalities in Hippocampal Functioning with Persistent Pain

(2012) A. A. Mutso et al.   JOURNAL OF NEUROSCIENCE

Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat

(2012) Livio Luongo et al.   NEUROPHARMACOLOGY

MicroRNA-320 induces neurite outgrowth by targeting ARPP-1

(2012) Robin E. White et al.   NEUROREPORT

Tests and models of nociception and pain in rodents

(2012) M. Barrot   NEUROSCIENCE

Differential effects of left/right neuropathy on rats’ anxiety and cognitive behavior

(2012) Hugo Leite-Almeida et al.   PAIN

Study of emotional and cognitive impairments in mononeuropathic rats: Effect of duloxetine and gabapentin

(2012) Stéphanie Grégoire et al.   PAIN

Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery

(2012) Moritz Lebe et al.   PAIN

Dysfunction in Fatty Acid Amide Hydrolase Is Associated with Depressive-Like Behavior in Wistar Kyoto Rats

(2012) K. Yaragudri Vinod et al.   PLoS One

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress

(2012) L. Tran et al.   PSYCHONEUROENDOCRINOLOGY

A Single Subanesthetic Dose of Ketamine Relieves Depression-like Behaviors Induced by Neuropathic Pain in Rats

(2011) Jing Wang et al.   ANESTHESIOLOGY

A Time-Dependent History of Mood Disorders in a Murine Model of Neuropathic Pain

(2011) Ipek Yalcin et al.   BIOLOGICAL PSYCHIATRY

Cross-national epidemiology of DSM-IV major depressive episode

(2011) Evelyn Bromet et al.   BMC Medicine

The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival

(2011) Bernadette Lehner et al.   CELL AND TISSUE RESEARCH

Intracerebroventricular 4-Methylcatechol (4-MC) Ameliorates Chronic Pain Associated with Depression-Like Behavior via Induction of Brain-Derived Neurotrophic Factor (BDNF)

(2011) Kayoko Fukuhara et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Brain-derived neurotrophic factor contributes to abdominal pain in irritable bowel syndrome

(2011) Yan-Bo Yu et al.   GUT

Hyporeactivity of ventral striatum towards incentive stimuli in unmedicated depressed patients normalizes after treatment with escitalopram

(2011) Meline Stoy et al.   JOURNAL OF PSYCHOPHARMACOLOGY

MicroRNA modulation in complex regional pain syndrome

(2011) Irina A Orlova et al.   Journal of Translational Medicine

Depression, Antidepressants and Neurogenesis: A Critical Reappraisal

(2011) Nicola D Hanson et al.   NEUROPSYCHOPHARMACOLOGY

Increased hippocampal glycine uptake and cognitive dysfunction after peripheral nerve injury

(2011) Daisuke Kodama et al.   PAIN

Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus

(2011) Adriana del Rey et al.   PAIN

Behavioral indices of ongoing pain are largely unchanged in male mice with tissue or nerve injury-induced mechanical hypersensitivity

(2011) Rochelle Urban et al.   PAIN

The specific disease burden of neuropathic pain: Results of a French nationwide survey

(2011) Nadine Attal et al.   PAIN

Immune system to brain signaling: Neuropsychopharmacological implications

(2011) Lucile Capuron et al.   PHARMACOLOGY & THERAPEUTICS

Curcumin ameliorates reserpine-induced pain–depression dyad: Behavioural, biochemical, neurochemical and molecular evidences

(2011) V. Arora et al.   PSYCHONEUROENDOCRINOLOGY

WAY-318068: a novel, potent and selective noradrenaline re-uptake inhibitor with activity in rodent models of pain and depression

(2010) GT Whiteside et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epigenetics and depression: current challenges and new therapeutic options

(2010) Marc Schroeder et al.   CURRENT OPINION IN PSYCHIATRY

Amitriptyline rather than lornoxicam ameliorates neuropathic pain-induced deficits in abilities of spatial learning and memory

(2010) Yifeng Hu et al.   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Increased Plasma Levels of Brain Derived Neurotrophic Factor (BDNF) in Patients with Fibromyalgia

(2010) Lisete Haas et al.   NEUROCHEMICAL RESEARCH

Social Interaction Prevents the Development of Depressive-Like Behavior Post Nerve Injury in Mice: A Potential Role for Oxytocin

(2010) Greg J. Norman et al.   PSYCHOSOMATIC MEDICINE

Candidate gene studies of fibromyalgia: a systematic review and meta-analysis

(2010) Young Ho Lee et al.   RHEUMATOLOGY INTERNATIONAL

Glutamatergic Modulators: The Future of Treating Mood Disorders?

(2010) Carlos Zarate et al.   HARVARD REVIEW OF PSYCHIATRY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

Prospect of a Dopamine Contribution in the Next Generation of Antidepressant Drugs: The Triple Reuptake Inhibitors

(2009) Bruno Guiard et al.   CURRENT DRUG TARGETS

Coronary artery disease and depression: Possible role of brain-derived neurotrophic factor and serotonin transporter gene polymorphisms

(2009) Bozzini   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Stress and IL-1β contribute to the development of depressive-like behavior following peripheral nerve injury

(2009) G J Norman et al.   MOLECULAR PSYCHIATRY

Behavioral models of pain states evoked by physical injury to the peripheral nerve

(2009) Linda S. Sorkin et al.   Neurotherapeutics

The impact of age on emotional and cognitive behaviours triggered by experimental neuropathy in rats

(2009) Hugo Leite-Almeida et al.   PAIN

NMDA NR2A and NR2B receptors in the rostral anterior cingulate cortex contribute to pain-related aversion in male rats

(2009) Ting-Ting Li et al.   PAIN

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833

(2009) Bing Hu et al.   PAIN

Durability of Therapeutic Response to Milnacipran Treatment for Fibromyalgia. Results of a Randomized, Double-Blind, Monotherapy 6-Month Extension Study

(2009) Don L. Goldenberg et al.   PAIN MEDICINE

Elevated level of metabotropic glutamate receptor 2/3 in the prefrontal cortex in major depression

(2009) Anteneh M. Feyissa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Exacerbated mechanical allodynia in rats with depression-like behavior

(2008) Qing Zeng et al.   BRAIN RESEARCH

Neuropathic pain is associated with depressive behaviour and induces neuroplasticity in the amygdala of the rat

(2008) Leonor Gonçalves et al.   EXPERIMENTAL NEUROLOGY

β2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain

(2008) Ipek Yalcin et al.   NEUROBIOLOGY OF DISEASE

Anxiety-like behaviour in rats with mononeuropathy is reduced by the analgesic drugs morphine and gabapentin

(2008) Kerstin Roeska et al.   PAIN

Sciatic nerve cuffing in mice: A model of sustained neuropathic pain

(2007) Malika Benbouzid et al.   EUROPEAN JOURNAL OF PAIN

Nabilone for the Treatment of Pain in Fibromyalgia

(2007) Ryan Quinlan Skrabek et al.   JOURNAL OF PAIN

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE