Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice

(2015) Wenjun Zhou et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of Corticostriatal Circuitry Relieves Chronic Neuropathic Pain

(2015) M. Lee et al.   JOURNAL OF NEUROSCIENCE

Nerve growth factor–induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain

(2015) Chau-Fu Cheng et al.   PAIN

Anti-interleukin-1β antibody prevents the occurrence of repeated restraint stress-induced alterations in synaptic transmission and long-term potentiation in the rat frontal cortex

(2015) Bartosz Bobula et al.   Pharmacological Reports

Diversity and plasticity of microglial cells in psychiatric and neurological disorders

(2015) Yutaka Nakagawa et al.   PHARMACOLOGY & THERAPEUTICS

Analgesic effect of total flavonoids from Sanguis draxonis on spared nerve injury rat model of neuropathic pain

(2015) Fu-Feng Chen et al.   PHYTOMEDICINE

An excitatory synapse hypothesis of depression

(2015) Scott M. Thompson et al.   TRENDS IN NEUROSCIENCES

Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling

(2014) Anna Dellarole et al.   BRAIN BEHAVIOR AND IMMUNITY

The anxiodepressive comorbidity in chronic pain

(2014) Ipek Yalcin et al.   Current Opinion in Anesthesiology

Long-term Potentiation at Spinal C-fiber Synapses: A Target for Pathological Pain

(2014) Xian-Guo Liu et al.   CURRENT PHARMACEUTICAL DESIGN

Anxiety- and Depression-Like Behavior and Impaired Neurogenesis Evoked by Peripheral Neuropathy Persist following Resolution of Prolonged Tactile Hypersensitivity

(2014) E. L. Dimitrov et al.   JOURNAL OF NEUROSCIENCE

Mirror-image pain is mediated by nerve growth factor produced from tumor necrosis factor alpha-activated satellite glia after peripheral nerve injury

(2014) Chau-Fu Cheng et al.   PAIN

Synapse rearrangements upon learning: from divergent–sparse connectivity to dedicated sub-circuits

(2014) Pico Caroni et al.   TRENDS IN NEUROSCIENCES

Interleukin-1β orchestrates underlying inflammatory responses in microglia via Krüppel-like factor 4

(2013) Deepak K. Kaushik et al.   JOURNAL OF NEUROCHEMISTRY

Induction of Thermal Hyperalgesia and Synaptic Long-Term Potentiation in the Spinal Cord Lamina I by TNF-  and IL-1  is Mediated by Glial Cells

(2013) D. Gruber-Schoffnegger et al.   JOURNAL OF NEUROSCIENCE

Maternal Deprivation Is Associated With Sex-Dependent Alterations in Nociceptive Behavior and Neuroinflammatory Mediators in the Rat Following Peripheral Nerve Injury

(2013) Nikita N. Burke et al.   JOURNAL OF PAIN

Learning and memory ... and the immune system

(2013) I. Marin et al.   LEARNING & MEMORY

Peri-sciatic administration of recombinant rat IL-1β induces mechanical allodynia by activation of src-family kinases in spinal microglia in rats

(2012) Xu-Hong Wei et al.   EXPERIMENTAL NEUROLOGY

Targeting IL-1 in depression

(2012) Michael Maes et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

(2012) Hyangin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Synaptic plasticity in depression: Molecular, cellular and functional correlates

(2012) W.N. Marsden   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Synaptic Structure and Function in the Mouse Somatosensory Cortex during Chronic Pain:In VivoTwo-Photon Imaging

(2012) Sun Kwang Kim et al.   NEURAL PLASTICITY

ARA290, a Peptide Derived from the Tertiary Structure of Erythropoietin, Produces Long-term Relief of Neuropathic Pain

(2011) Maarten Swartjes et al.   ANESTHESIOLOGY

Peripheral Nerve Injury Alters Blood-Spinal Cord Barrier Functional and Molecular Integrity through a Selective Inflammatory Pathway

(2011) S. Echeverry et al.   JOURNAL OF NEUROSCIENCE

Peripheral Nerve Injury Leads to Working Memory Deficits and Dysfunction of the Hippocampus by Upregulation of TNF-α in Rodents

(2011) Wen-Jie Ren et al.   NEUROPSYCHOPHARMACOLOGY

Chronic neuropathic pain-like behavior correlates with IL-1β expression and disrupts cytokine interactions in the hippocampus

(2011) Adriana del Rey et al.   PAIN

Localization of Dysfunction in Major Depressive Disorder: Prefrontal Cortex and Amygdala

(2010) Elisabeth A. Murray et al.   BIOLOGICAL PSYCHIATRY

Linking the cytokine and neurocircuitry hypotheses of depression: A translational framework for discovery and development of novel anti-depressants

(2010) Timothy M. Piser   BRAIN BEHAVIOR AND IMMUNITY

The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: The role of tumor necrosis factor-α

(2010) Yi Zhong et al.   BRAIN BEHAVIOR AND IMMUNITY

Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: Effects on brain cytokines and neurotrophins

(2010) Hassen Al-Amin et al.   EXPERIMENTAL NEUROLOGY

Peripheral Nerve Injury and TRPV1-Expressing Primary Afferent C-Fibers Cause Opening of the Blood-Brain Barrier

(2010) Simon Beggs et al.   Molecular Pain

Role of interleukin-1β during pain and inflammation

(2009) Ke Ren et al.   BRAIN RESEARCH REVIEWS

Stress and IL-1β contribute to the development of depressive-like behavior following peripheral nerve injury

(2009) G J Norman et al.   MOLECULAR PSYCHIATRY

A neurocognitive model of attention to pain: Behavioral and neuroimaging evidence

(2009) Valéry Legrain et al.   PAIN

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

(2008) Wayne C. Drevets et al.   Brain Structure & Function

Interleukin-1β: a bridge between inflammation and excitotoxicity?

(2008) Birgit Fogal et al.   JOURNAL OF NEUROCHEMISTRY

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation

Selective Activation of Microglia in Spinal Cord but Not Higher Cortical Regions Following Nerve Injury in Adult Mouse

(2008) Fuxing Zhang et al.   Molecular Pain

Relationships among pain, anxiety, and depression in primary care

(2007) Adrienne J. Means-Christensen et al.   DEPRESSION AND ANXIETY