Epigenetic modulation of chronic anxiety and pain by histone deacetylation

Vorinostat, a HDAC inhibitor, showed anti-osteoarthritic activities through inhibition of iNOS and MMP expression, p38 and ERK phosphorylation and blocking NF-κB nuclear translocation

(2013) Hui-ming Zhong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Rice NAD+-Dependent Histone Deacetylase OsSRT1 Targets Preferentially to Stress- and Metabolism-Related Genes and Transposable Elements

(2013) Xiaochao Zhong et al.   PLoS One

The role of the anteriolateral bed nucleus of the stria terminalis in stress-induced nociception

(2012) Lee Tran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Altered expression of glucocorticoid receptor and corticotropin-releasing factor in the central amygdala in response to elevated corticosterone

(2012) Lee Tran et al.   BEHAVIOURAL BRAIN RESEARCH

Importance of stress receptor-mediated mechanisms in the amygdala on visceral pain perception in an intrinsically anxious rat

(2012) A. C. Johnson et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Epigenetic Mechanisms for the Early Environmental Regulation of Hippocampal Glucocorticoid Receptor Gene Expression in Rodents and Humans

(2012) Tie Yuan Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Importance of epigenetic mechanisms in visceral pain induced by chronic water avoidance stress

(2012) L. Tran et al.   PSYCHONEUROENDOCRINOLOGY

Orphanin FQ/Nociceptin Activates Nuclear Factor Kappa B

(2011) Courtney L. Donica et al.   Journal of Neuroimmune Pharmacology

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

(2011) Simon C. Biddie et al.   MOLECULAR CELL

Lateralized amygdala activation: Importance in the regulation of anxiety and pain behavior

(2011) Lee Tran et al.   PHYSIOLOGY & BEHAVIOR

Elevated corticosterone in the amygdala leads to persistant increases in anxiety-like behavior and pain sensitivity

(2010) Brent Myers et al.   BEHAVIOURAL BRAIN RESEARCH

Epigenetic Changes in the Hypothalamic Proopiomelanocortin and Glucocorticoid Receptor Genes in the Ovine Fetus after Periconceptional Undernutrition

(2010) Adam Stevens et al.   ENDOCRINOLOGY

Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms

(2010) Romain–Daniel Gosselin et al.   GASTROENTEROLOGY

Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity

(2010) B. Schwer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF- B p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells

(2010) Q.-Y. Choo et al.   RHEUMATOLOGY

Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation

(2009) Jessica K. Alexander et al.   BRAIN BEHAVIOR AND IMMUNITY

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Vorinostat interferes with Wnt and NF-κB pathways in the M-07e cell line

(2009) S Galimberti et al.   LEUKEMIA

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

Pharmacodynamic Assessment of Histone Deacetylase Inhibitors: Infrared Vibrational Spectroscopic Imaging of Protein Acetylation

(2008) Tsoching Chen et al.   ANALYTICAL CHEMISTRY

Evolutionarily Conserved Glucocorticoid Regulation of Corticotropin-Releasing Factor Expression

(2008) Meng Yao et al.   ENDOCRINOLOGY

Pro- and Anti-Nociceptive Effects of Corticotropin-Releasing Factor (CRF) in Central Amygdala Neurons Are Mediated Through Different Receptors

(2008) Guangchen Ji et al.   JOURNAL OF NEUROPHYSIOLOGY

Brain Chromatin Remodeling: A Novel Mechanism of Alcoholism

(2008) S. C. Pandey et al.   JOURNAL OF NEUROSCIENCE

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE

The social environment and the epigenome

(2007) Moshe Szyf et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS