Article
Materials Science, Paper & Wood
Zhen Yuan, Junwen Cheng, Guangqian Lan, Fei Lu
Summary: Antibacterial and moisturizing dressings were fabricated using cellulose/konjac glucomannan/Ag nanoparticle composites, with properties easily manipulated by adjusting composition ratios. The CK7-Ag3 aerogel showed excellent antibacterial activity and biocompatibility, enabling complete wound recovery within just 14 days.
Article
Biochemistry & Molecular Biology
Liying Huang, Huanglong Lin, Nitong Bu, Jie Pang, Ruojun Mu
Summary: In this research, PVP microfibers incorporated water-in-oil (W/O) emulsions were prepared. The W/O emulsions consisted of hexadecyl konjac glucomannan (HKGM, emulsifier), corn oil (oil phase), and purple corn anthocyanins (PCAs, water phase). The emulsions and microfibers were characterized using CLSM, SEM, FT-IR, Raman, and NMR spectroscopy. The results demonstrated that the addition of PCAs improved the water resistance, mechanical strength, antioxidation, and antibacterial activity of the microfiber films. The microfiber films also exhibited controlled release of PCAs, making them suitable for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Rixiang Su, Wei Su, Jinyun Cai, Lei Cen, Shanshan Huang, Yu Wang, Peiyuan Li
Summary: In this study, a nanocomposite drug was developed to overcome the limitations of photo-sensitizers and form composite films with improved stability and mechanical properties. The nanocomposite drug showed good biocompatibility and PDT antibacterial effects, making it a promising nano-antibacterial agent for the treatment of bacterial infections and wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Chemistry, Applied
Yongsheng Ni, Jing Sun, Jianlong Wang
Summary: This paper presents a new strategy for developing konjac glucomannan-based antibacterial films with a broad-spectrum antibacterial activity. The films, incorporating CNMo nanocomposites, show excellent performances in terms of structural, mechanical, and thermal properties, as well as hydrophobicity, prolonging the shelf life of cherry tomatoes. Hemolysis and cells experiment confirm the safety of the film, indicating potential applications in antibacterial packaging.
CARBOHYDRATE POLYMERS
(2021)
Article
Food Science & Technology
Zhe Liu, Dehui Lin, Rui Shen, Runguang Zhang, Liu Liu, Xingbin Yang
Summary: The study developed edible films based on konjac glucomannan (KGM) loaded with different concentrations of thyme essential oil (TEO) and found that TEO distribution influenced film roughness, hydrophilic characteristics decreased with increasing TEO concentrations, and antioxidant capacities and antibacterial activities of the films improved.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Biochemistry & Molecular Biology
Jingting Xu, Ying Yang, Lu Liu, Xin Huang, Chunhua Wu, Jie Pang, Renhui Qiu, Shuyi Wu
Summary: In this study, bio-fibers were prepared using different channel shapes and the dynamical behaviors of macromolecule clusters in flow fields were simulated. The results show that the elongational flow with increasing extension rates produced fibers with improved tensile strength and strain. The channel shapes significantly influence flow fields, dynamical behaviors of molecule clusters, the morphology of fibers, and tensile performances.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Shancan Wang, Mingyu Li, Beibei He, Yueyuan Yong, Jie Zhu
Summary: Currently, food waste and the potential hazards of petroleum-based food packaging films have become serious issues, leading to increased focus on the development of new food packaging materials. In this study, a novel packaging film based on sodium alginate and konjac glucomannan blended with tea polyphenols was prepared. The film exhibited excellent microstructure, mechanical properties, barrier property, oxidation property, antibacterial activity, and stability. The results also showed that tea polyphenols could affect bacterial growth by interacting with peptidoglycan in the cell wall. Additionally, the film demonstrated excellent preservation effects in beef and apples, indicating its potential as a bioactive packaging material for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Shikai Zhang, Ziyang He, Fangzhou Xu, Yue Cheng, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Peng Wu
Summary: The addition of ZPEO in KGM films can modify their properties, leading to high-performance composite films with enhanced tensile strength, water contact angle, and antibacterial properties, as well as the ability to slowly release essential oils.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Mengya Ding, Xiaojie Wang, Jia Man, Jianyong Li, Yinghua Qiu, Yongqi Zhang, Maocheng Ji, Jianfeng Li
Summary: In this study, a novel fiber-type medical dressing with excellent breathable, antibacterial, and hemostatic qualities was created using sodium alginate (SA), microcrystalline cellulose (MCC), polyvinyl alcohol (PVA), and Euphorbia humifusa Willd (EHW) based on microfluidic spinning technology. The dressings have been proven to have potent antibacterial and hemostatic properties as well as the ability to considerably speed up wound healing and skin tissue regeneration in the in-vitro and in-vivo tests. This innovative fiber-type medical dressing containing SA, MCC, PVA, and EHW has enormous potential for managing wounds caused by bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Meng Wang, Yun-Cheng Li, Fan-Bing Meng, Qiao Wang, Zheng-Wu Wang, Da-Yu Liu
Summary: In this study, honeysuckle leaf extract was added to the CMKH composite film. The addition of honeysuckle leaf extract slightly decreased the water vapor barrier properties of the film, but completely blocked UV transmission. The film with honeysuckle leaf extract showed higher elongation at break and exhibited strong antioxidant and antimicrobial activities.
Article
Biochemistry & Molecular Biology
Wanzhen Xie, Yu Du, Shuyi Yuan, Jie Pang
Summary: Active composite films were developed by incorporating different concentrations of dihydromyricetin (DMY) into konjac glucomannan (KGM)/gellan gum (GG) matrix. The films showed good physicochemical properties, enhanced antioxidant and antimicrobial activities, as well as promising application in food packaging.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Agriculture, Multidisciplinary
Ziqiang Duan, Yuntao Wang, Xiao Yu, Nan Wu, Jie Pang, Yanhong Bai
Summary: In this study, the effects of konjac oligo-glucomannan (KOG) on the emulsifying properties of myofibrillar protein (MP) were investigated. It was found that the addition of KOG altered the tertiary conformation of MP, resulting in improved emulsifying activity, decreased particle size, and improved physical stability of the emulsion. The findings suggest that KOG interacts with MP at the oil-water interface, forming a stable interface film to enhance the emulsifying properties of MP.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Biochemistry & Molecular Biology
Hengji Zhao, Yushu Zhang, Chao Zhou, Chunling Zhang, Bo Liu
Summary: Natural polysaccharide-based hydrogels provide effective skin protection during trauma and exhibit good antibacterial properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Dongling Qiao, Jieyi Lu, Wenjuan Shi, Hao Li, Liang Zhang, Fatang Jiang, Binjia Zhang
Summary: Deacetylation enhances chain interactions, reduces crystallite formation, improves hydrophobicity and mechanical performance, and increases matrix flexibility and elongation at break in KGM-based composite films.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Applied
Yongsheng Ni, Jingyao Wang, Jing Sun, Jianlong Wang
Summary: This study successfully developed functional KCNGO films with excellent performance, showcasing a potential application in food preservation through quasi-pasteurization strategy.
Article
Food Science & Technology
Ruojun Mu, Jianshe Chen
Summary: Saliva forms a typical bio-interface in the oral cavity and plays a crucial role in food oral processing. Understanding the formations, structures, and interactions at the saliva bio-interface is essential for manipulating food and sensory perception.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Hui Qiu, Xiaowei Qu, Yujiao Zhang, Su Chen, Yizhong Shen
Summary: This study proposes a novel method based on microfluidic wet-fusing spinning chemistry to construct hierarchical structures of MXene-based fiber fabrics, which enables the fabrication of MFF electrodes with ultrastrong toughness, high conductivity, and easily machinable properties. The designed morphology and microstructure provide a viable solution for large-scale preparation of conductive fabric electrodes while simultaneously enhancing mechanical strength and electrochemical performance.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Liangliang Zhou, Jingtao Han, Jijun Xiao, Xiaoning Yang, Su Chen
Summary: This study demonstrates a microfluidic-assisted self-assembly process to construct a hydroxyl functionalized boron nitride nanosheets/graphene oxide/thermoplastic polyurethane composite nanofiber film. The self-assembled film shows a massive enhancement of mechanical strength by adding only 0.3 wt% of hydroxyl functionalized boron nitride nanosheets and graphene oxide. This microfluidic-assisted self-assembly strategy provides a constructive entry point for the rational design of nanofibers.
Article
Chemistry, Multidisciplinary
An-Quan Xie, Qing Li, Yiran Xi, Liangliang Zhu, Su Chen
Summary: Photonic crystals (PCs) with a periodically arranged structure have drawn significant attention for their ability to regulate photon motion and block specific electromagnetic waves. PCs have various applications in color signage, display, sensors, and optoelectronic devices. This review focuses on the research progress of crack-free PC assembly methods, including the fundamental theory, formation mechanisms of assembly defects, and strategies for defect elimination.
ACCOUNTS OF MATERIALS RESEARCH
(2023)
Article
Nanoscience & Nanotechnology
Rong Chen, Zhiting Liu, Tingting Cui, Xiaoying Zhang, Cai-Feng Wang, Guo-Xing Li, Gefei Wang, Su Chen
Summary: This study presents a gel-nanofiber material that combines the advantages of hydrogels and nanofibers for wound healing. The material overcomes the limitations of low mechanical strength and self-adhesion in hydrogels and the inadequate healing environment created by nanofibers. The gel-nanofiber dressing exhibits high tensile strength, excellent air permeability, self-adhesion, and positive hydrophilicity. It demonstrates good cytocompatibility and antibacterial properties, leading to a high wound-healing rate and substantial granulation growth within a short time period.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Engineering, Environmental
Yaru Liu, Jiacheng Guo, Jia-Wei Wang, Lihua Han, Liangliang Zhu, Su Chen
Summary: The microstructure of ordered photothermal materials constructed using colloidal photonic crystals significantly improves interfacial solar evaporation. These materials demonstrate excellent internal light reflection and water wettability, achieving high solar vaporization rates and exhibiting colorful appearance. The controllable methodology for ordered architecture construction inspires the development of novel nanostructured and multifunctional photothermal materials for solar evaporation.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Shuzhen Yu, Yongchun Hou, Qijie Jin, Liangliang Zhu, Su Chen
Summary: A novel biomimetic photocatalyst design approach is proposed to improve the catalytic efficiency by slow photon mechanism. By coupling photonic crystals and photocatalyst of ChlCu, a composite photocatalytic film is sprayed onto external surfaces, converting CO2 and water into CO and oxygen. This opens new possibilities for CO2 converting and provides new ideas for greenhouse gas capture and utilization.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Yifeng Chen, Anze Shen, Jiazhuang Guo, Liangliang Zhu, Ge Li, Ying Qin, Xiaowei Qu, Cai-Feng Wang, Su Chen
Summary: A robust aluminum-based microfluidic chip reaction platform is developed for the rapid and continuous synthesis of highly fluorescent carbon dots (CDs). The as-prepared CDs possess excellent optical properties and can be combined with polymers to form nanofiber films with enhanced mechanical properties. This work presents a new method for the synthesis of nanomaterials and demonstrates the potential of microfluidic techniques in the preparation of high-performance CDs and CDs/polymers nanofiber films.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Chemical
Ting Dong, Yi-Xin Zhou, Jie Yong, Qing Li, Su Chen
Summary: In this paper, a double-pore composite nanofiber membrane with highly efficient and antibacterial filtration properties was reported. The membrane was fabricated through microfluidic spinning by coating zeolite imidazole framework-8 nanoparticles with curcumin. The membrane exhibited excellent particulate matter removal efficiency and antibacterial properties.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Review
Polymer Science
Yan Song, Xiao-Qing Yu, Su Chen
Summary: Fiber-spinning chemistry (FSC) is a promising micro-reaction platform due to its high specific surface area, efficient heat and mass transfer, and enhanced reaction rate. This review highlights the latest advancements in FSC in terms of preparation mechanisms and technical advantages, with emphasis on microfluidic spinning, electro-microfluidic spinning, and microfluidic blow spinning strategies. The application of FSC in the synthesis of fluorescent nanomaterials, nonweaving for multidimensional fibers, and all-weather smart textiles is summarized, and the future perspectives are discussed.
JOURNAL OF POLYMER SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Rui Cheng, Zhi-Bin Liang, Haixia Shen, Jiazhuang Guo, Cai-Feng Wang, Su Chen
Summary: In this work, color-tunable fluorescent formamidinium lead halogen (FAPbX3, X = Cl, Br, I) PQDs/polymer core-shell nanofiber films were fabricated using a microfluidic electrospinning method. The high stability and PL quantum yield make these films highly promising for optoelectronic applications.
CHINESE CHEMICAL LETTERS
(2023)
Article
Materials Science, Multidisciplinary
Tong Tong, Chang Liu, Jing Xu, Huihua Min, Su Chen, Yinong Lyu, Chongguang Lyu
Summary: In this work, ReRAM devices based on lead-free double perovskite Cs2AgEuBr6 were reported for the first time. These devices exhibited robust and reproducible bipolar switching behavior and long retention time. This study will inspire the further design of nonvolatile memory devices and other electronics using lead-free halide perovskite.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Applied
Wenze Wang, Liang Zhang, Puyuan Hu, Yuxuan Wang, Xinyi Jin, Rui Chen, Wentao Zhang, Yongsheng Ni, Jianlong Wang
Summary: A novel packaging film was developed to tackle microbial contamination and spoilage during pork storage by incorporating shellac-encapsulated cinnamaldehyde nano-capsules (SNCs) and chitosan (CS) film matrix. The film demonstrated controlled release behavior and antimicrobial properties, effectively extending the freshness duration of pork and regulating environmental moisture.
Article
Chemistry, Multidisciplinary
Hui Qiu, Xiaowei Qu, Yujiao Zhang, Su Chen, Yizhong Shen
Summary: A method based on microfluidic wet-fusing spinning chemistry is proposed to construct hierarchical structure of MXene-based fiber fabrics with enhanced mechanical strength and electrochemical performance. The strategy provides a feasible solution for large-scale preparation of conductive fabric electrodes.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Liangliang Zhu, Liang Tian, Siyi Jiang, Lihua Han, Yunzheng Liang, Qing Li, Su Chen
Summary: This review summarizes the recent progress in photothermal regulation, focusing on solar heating and passive cooling, and their manipulating strategies. The underlying mechanisms and criteria of highly efficient photothermal regulation are discussed, along with the recent developments of applications in clean energy and environmental areas. The review provides a comprehensive overview of photothermal regulation strategies and highlights the potential for future development and challenges.
CHEMICAL SOCIETY REVIEWS
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)