Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivo
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Increased NHE1 expression is targeted by specific inhibitor cariporide to sensitize resistant breast cancer cells to doxorubicin in vitro and in vivo
Authors
Keywords
NHE-1, Cariporide, Sensitivity, MCF-7/ADR, MDR, Chemotherapy
Journal
BMC CANCER
Volume 19, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-03-08
DOI
10.1186/s12885-019-5397-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Breast cancer in young women and prognosis: How important are proliferation markers?
- (2017) Hanna Fredholm et al. EUROPEAN JOURNAL OF CANCER
- Cancer cell behaviors mediated by dysregulated pH dynamics at a glance
- (2017) Katharine A. White et al. JOURNAL OF CELL SCIENCE
- NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion
- (2017) Rui Xie et al. ONCOLOGY REPORTS
- Na + /H + antiporter (NHE1) and lactate/H + symporters (MCTs) in pH homeostasis and cancer metabolism
- (2016) Laurent Counillon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Cancer statistics in China, 2015
- (2016) Wanqing Chen et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Glioma-mediated microglial activation promotes glioma proliferation and migration: roles of Na+/H+exchanger isoform 1
- (2016) Wen Zhu et al. CARCINOGENESIS
- Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment
- (2016) Anne Poder Andersen et al. Molecular Cancer
- Manipulation of Intracellular pH in Cancer Cells by NHE1 Inhibitors
- (2016) Francesca Aredia et al. PROTEIN AND PEPTIDE LETTERS
- ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
- (2016) Takaaki Oba et al. Oncotarget
- Na+/H+ exchange in the tumour microenvironment: does NHE1 drive breast cancer carcinogenesis?
- (2015) Schammim R. Amith et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Elevation of miR-27b by HPV16 E7 inhibits PPARγ expression and promotes proliferation and invasion in cervical carcinoma cells
- (2015) SHIMENG ZHANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Induction of Heme Oxygenase-1 by Na+-H+Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells
- (2015) Dan Ma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased H+ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression
- (2015) Bree K Grillo-Hill et al. eLife
- A Novel NHE1-Centered Signaling Cassette Drives Epidermal Growth Factor Receptor–Dependent Pancreatic Tumor Metastasis and Is a Target for Combination Therapy
- (2015) Rosa Angela Cardone et al. NEOPLASIA
- Knockdown of MDR1 Increases the Sensitivity to Adriamycin in Drug Resistant Gastric Cancer Cells
- (2014) Chun-Yu Zhu et al. Asian Pacific Journal of Cancer Prevention
- Dasatinib reverses the multidrug resistance of breast cancer MCF-7 cells to doxorubicin by downregulating P-gp expression via inhibiting the activation of ERK signaling pathway
- (2014) Ting Chen et al. CANCER BIOLOGY & THERAPY
- Talin regulates moesin–NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis
- (2014) Brian T. Beaty et al. JOURNAL OF CELL BIOLOGY
- Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
- (2013) Matthew Brentnall et al. BMC CELL BIOLOGY
- Regulation of the Na+/H+ Exchanger (NHE1) in Breast Cancer Metastasis
- (2013) S. R. Amith et al. CANCER RESEARCH
- NHE-1: Still a viable therapeutic target
- (2013) Morris Karmazyn JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Fluorouracil, epirubicin, and cyclophosphamide (FEC-75) followed by paclitaxel plus trastuzumab versus paclitaxel plus trastuzumab followed by FEC-75 plus trastuzumab as neoadjuvant treatment for patients with HER2-positive breast cancer (Z1041): a randomised, controlled, phase 3 trial
- (2013) Aman U Buzdar et al. LANCET ONCOLOGY
- Cariporide sensitizes leukemic cells to tumor necrosis factor related apoptosis-inducing ligand by up-regulation of death receptor 5 via endoplasmic reticulum stress–CCAAT/enhancer binding protein homologous protein dependent mechanism
- (2013) Huawen Li et al. LEUKEMIA & LYMPHOMA
- Na+-H+ Exchanger, pH Regulation and Cancer
- (2013) Stephan J. Reshkin et al. Recent Patents on Anti-Cancer Drug Discovery
- Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function
- (2012) M. J. White et al. BLOOD
- Blocking the Na+/H+ exchanger 1 with cariporide (HOE642) reduces the hypoxia-induced invasion of human tongue squamous cell carcinoma
- (2012) C. Lv et al. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
- CD44+/CD24- phenotype contributes to malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma
- (2012) Yan Lin et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Structural and functional insights into the cardiac Na+/H+ exchanger
- (2012) Brian L. Lee et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems
- (2012) Oktay Tacar et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Caspases and Kinases in a Death Grip
- (2009) Manabu Kurokawa et al. CELL
- The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer
- (2009) Wen-Qing Hu et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Stromal gene expression predicts clinical outcome in breast cancer
- (2008) Greg Finak et al. NATURE MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now