Induction of Heme Oxygenase-1 by Na+-H+Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells

Protein Kinase C-Beta Inhibition Induces Apoptosis and Inhibits Cell Cycle Progression in Acquired Immunodeficiency Syndrome–Related Non-Hodgkin Lymphoma Cells

(2016) Nakhle S. Saba et al.   JOURNAL OF INVESTIGATIVE MEDICINE

HS-438, a new inhibitor of Imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia

(2014) Sun-Mi Yun et al.   CANCER LETTERS

Discontinuation of tyrosine kinase inhibitors and new approaches to target leukemic stem cells: Treatment-free remission as a new goal in chronic myeloid leukemia

(2014) Massimo Breccia et al.   CANCER LETTERS

Heme Oxygenase-1 Mediates Oxidative Stress and Apoptosis in Coxsackievirus B3-Induced Myocarditis

(2014) Oana N. Ursu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Protein kinase C-β mediates neuronal activation of Na+/H+ exchanger-1 during glutamate excitotoxicity

(2014) Bo Kyung Lee et al.   CELLULAR SIGNALLING

Successful treatment of Philadelphia chromosome-positive mixed phenotype acute leukemia by appropriate alternation of second-generation tyrosine kinase inhibitors according to BCR-ABL1 mutation status

(2014) Chika Kawajiri et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy

(2014) Tsu-Kung Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Patient With Chronic Myeloid Leukemia in Complete Cytogenetic Response: What Does It Mean, and What Does One Do Next?

(2014) David Marin   JOURNAL OF CLINICAL ONCOLOGY

BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian chronic myeloid leukemia patients—Frequency and clinical outcome

(2014) Marjanu Hikmah Elias et al.   LEUKEMIA RESEARCH

In silico identification of novel kinase inhibitors targeting wild-type and T315I mutant ABL1 from FDA-approved drugs

(2014) Huai-long Xu et al.   Molecular BioSystems

IMATINIB IN CHRONIC MYELOID LEUKEMIA: AN OVERVIEW

(2014) Tomasz Sacha   Mediterranean Journal of Hematology and Infectious Diseases

TREATMENT RECOMMENDATIONS FOR CHRONIC MYELOID LEUKEMIA

(2014) Michele Baccarani et al.   Mediterranean Journal of Hematology and Infectious Diseases

Identifying the Time to Change BCR-ABL Inhibitor Therapy in Patients with Chronic Myeloid Leukemia

(2013) Michael R. Savona et al.   ACTA HAEMATOLOGICA

Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo

(2013) Gloria Lutzny et al.   CANCER CELL

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

(2013) B. Wegiel et al.   CANCER RESEARCH

Resistance to Tyrosine Kinase Inhibition Therapy for Chronic Myelogenous Leukemia: A Clinical Perspective and Emerging Treatment Options

(2013) Elias J. Jabbour et al.   Clinical Lymphoma Myeloma & Leukemia

Nuclear Translocation of Heme Oxygenase-1 Confers Resistance to Imatinib in Chronic Myeloid Leukemia Cells

(2013) Daniele Tibullo et al.   CURRENT PHARMACEUTICAL DESIGN

PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice

(2013) Francesco Oriente et al.   DIABETOLOGIA

Improved survival in chronic myeloid leukemia since the introduction of imatinib therapy: a single-institution historical experience

(2012) H. Kantarjian et al.   BLOOD

Comprehensive therapeutic outcomes of frontline imatinib mesylate in newly diagnosed chronic phase chronic myeloid leukemia patients in Korea: feasibility assessment of current ELN recommendation

(2012) Dongho Kim et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Targeting PKC-mediated signal transduction pathways using enzastaurin to promote apoptosis in acute myeloid leukemia-derived cell lines and blast cells

(2011) Peter P. Ruvolo et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart

(2010) Guangwu Wang et al.   CIRCULATION

Heme oxygenase-1 promotes angiogenesis in urothelial carcinoma of the urinary bladder

(2010) Miyake   ONCOLOGY REPORTS

Protein Kinase B/Akt Phosphorylates and Inhibits the Cardiac Na +/ H + Exchanger NHE1

(2008) Andrew K. Snabaitis et al.   CIRCULATION RESEARCH

The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress

(2008) Yong Pil Hwang et al.   FEBS LETTERS

Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice

(2008) Gabriele Sass et al.   INTERNATIONAL JOURNAL OF CANCER

Dual roles of Nrf2 in cancer

(2008) A LAU et al.   PHARMACOLOGICAL RESEARCH

Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice

(2007) Laura E. Randle et al.   TOXICOLOGY