Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita

Mechanisms of erythrocyte development and regeneration: implications for regenerative medicine and beyond

(2018) Emery H. Bresnick et al.   DEVELOPMENT

Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors

(2017) John C. Zinder et al.   GENES & DEVELOPMENT

p53 Mediates Failure of Human Definitive Hematopoiesis in Dyskeratosis Congenita

(2017) Wilson Chun Fok et al.   Stem Cell Reports

Posttranscriptional manipulation of TERC reverses molecular hallmarks of telomere disease

(2016) Baris Boyraz et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects

(2016) Siddharth Shukla et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis–emphysema

(2016) Susan E. Stanley et al.   Science Translational Medicine

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects

(2016) Siddharth Shukla et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita

(2015) Hemanth Tummala et al.   JOURNAL OF CLINICAL INVESTIGATION

Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages

(2015) Andrea Ditadi et al.   NATURE CELL BIOLOGY

Poly(A)-specific ribonuclease (PARN) mediates 3′-end maturation of the telomerase RNA component

(2015) Diane H Moon et al.   NATURE GENETICS

Human Telomerase RNA Processing and Quality Control

(2015) Chi-Kang Tseng et al.   Cell Reports

Telomere length in inherited bone marrow failure syndromes

(2014) B. P. Alter et al.   HAEMATOLOGICA

Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells

(2014) Christopher M Sturgeon et al.   NATURE BIOTECHNOLOGY

Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs

(2013) Thomas Winkler et al.   JOURNAL OF CLINICAL INVESTIGATION

TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends

(2012) Franklin L. Zhong et al.   CELL

The telomere syndromes

(2012) Mary Armanios et al.   NATURE REVIEWS GENETICS

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

(2011) Luis F. Z. Batista et al.   NATURE

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA