Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs

Human telomere disease due to disruption of the CCAAT box of the TERC promoter

(2012) A. M. Aalbers et al.   BLOOD

Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

(2012) K. Hoffmeyer et al.   SCIENCE

Dyskeratosis congenita and the DNA damage response

(2011) Michael Kirwan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Telomere dynamics in dyskeratosis congenita: the long and the short of iPS

(2011) Suneet Agarwal et al.   CELL RESEARCH

Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives

(2011) Shiran Yehezkel et al.   Epigenetics

Constitutional telomerase mutations are genetic risk factors for cirrhosis

(2011) Rodrigo T. Calado et al.   HEPATOLOGY

Telomerase gene mutations are associated with cirrhosis formation

(2011) Daniel Hartmann et al.   HEPATOLOGY

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

(2011) Luis F. Z. Batista et al.   NATURE

Concise Review: Genomic Stability of Human Induced Pluripotent Stem Cells

(2011) Kristen Martins-Taylor et al.   STEM CELLS

Natural History of Pulmonary Fibrosis in Two Subjects With the Same Telomerase Mutation

(2010) Souheil El-Chemaly et al.   CHEST

Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

(2010) Suneet Agarwal et al.   NATURE

Alternative lengthening of telomeres: models, mechanisms and implications

(2010) Anthony J. Cesare et al.   NATURE REVIEWS GENETICS

Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations

(2010) Alberto Diaz de Leon et al.   PLoS One

RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1  as critical for telomerase function in murine embryonic stem cells

(2010) M. Coussens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomere length is inherited with resetting of the telomere set-point

(2010) Y. J. Chiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging

(2009) Mary Armanios et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Telomere length maintenance in stem cell populations

(2009) Nicholas D. Allen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dyskeratosis congenita, stem cells and telomeres

(2009) Michael Kirwan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells

(2009) R. T. Calado et al.   BLOOD

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

(2009) Rosa M. Marion et al.   Cell Stem Cell

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

(2009) Yoshinori Yoshida et al.   Cell Stem Cell

Dyskeratosis Congenita

(2009) Sharon A. Savage et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telomere length measurement by a novel monochrome multiplex quantitative PCR method

(2009) R. M. Cawthon   NUCLEIC ACIDS RESEARCH

A Spectrum of Severe Familial Liver Disorders Associate with Telomerase Mutations

(2009) Rodrigo T. Calado et al.   PLoS One

Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

(2009) R. T. Calado et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

(2009) A. S. Venteicher et al.   SCIENCE

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Generation of human-induced pluripotent stem cells

(2008) In-Hyun Park et al.   Nature Protocols

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS