Enhancing co-translational folding of heterologous protein by deleting non-essential ribosomal proteins in Pichia pastoris

Steady-state structural fluctuation is a predictor of the necessity of pausing-mediated co-translational folding for small proteins

(2018) Wenxi Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris : A review

(2018) Zhiliang Yang et al.   BIOTECHNOLOGY ADVANCES

Metabolic engineering of Pichia pastoris for production of isobutanol and isobutyl acetate

(2018) Wiparat Siripong et al.   Biotechnology for Biofuels

The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan

(2017) Nitish Mittal et al.   Nature Communications

Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

(2016) Marie A. Hanebuth et al.   Nature Communications

Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells

(2016) Xinlei Lian et al.   PLoS Genetics

Quo vadis? The challenges of recombinant protein folding and secretion in Pichia pastoris

(2015) Verena Puxbaum et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Combined strategies for improving expression of Citrobacter amalonaticus phytase in Pichia pastoris

(2015) Cheng Li et al.   BMC BIOTECHNOLOGY

Identification of Missing Proteins Defined by Chromosome-Centric Proteome Project in the Cytoplasmic Detergent-Insoluble Proteins

(2015) Yang Chen et al.   JOURNAL OF PROTEOME RESEARCH

Codon Usage Influences the Local Rate of Translation Elongation to Regulate Co-translational Protein Folding

(2015) Chien-Hung Yu et al.   MOLECULAR CELL

Transfer RNAs Mediate the Rapid Adaptation of Escherichia coli to Oxidative Stress

(2015) Jiayong Zhong et al.   PLoS Genetics

Optimization of Translation Profiles Enhances Protein Expression and Solubility

(2015) Anne-Katrin Hess et al.   PLoS One

Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production

(2014) Mudassar Ahmad et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Improved production of a recombinant Rhizomucor miehei lipase expressed in Pichia pastoris and its application for conversion of microalgae oil to biodiesel

(2014) Jinjin Huang et al.   Biotechnology for Biofuels

Rational design of translational pausing without altering the amino acid sequence dramatically promotes soluble protein expression: A strategic demonstration

(2014) Wei Chen et al.   JOURNAL OF BIOTECHNOLOGY

Ribosome Assembly Factors Pwp1 and Nop12 Are Important for Folding of 5.8S rRNA during Ribosome Biogenesis in Saccharomyces cerevisiae

(2014) J. Talkish et al.   MOLECULAR AND CELLULAR BIOLOGY

Delayed Ras/PKA signaling augments the unfolded protein response

(2014) D. Pincus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cotranslational Function of Ribosome-Associated Hsp70 in Eukaryotic Protein Homeostasis

(2013) Felix Willmund et al.   CELL

Translation elongation can control translation initiation on eukaryotic mRNAs

(2013) Dominique Chu et al.   EMBO JOURNAL

Ribosome Biogenesis in the Yeast Saccharomyces cerevisiae

(2013) John L. Woolford et al.   GENETICS

Quantitative iTRAQ LC–MS/MS proteomics reveals the cellular response to heterologous protein overexpression and the regulation of HAC1 in Pichia pastoris

(2013) Xiao-qiong Lin et al.   Journal of Proteomics

Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific

(2013) Tong Wang et al.   NUCLEIC ACIDS RESEARCH

Synthetic Core Promoters for Pichia pastoris

(2013) Thomas Vogl et al.   ACS Synthetic Biology

Combined utilization of lipase-displaying Pichia pastoris whole-cell biocatalysts to improve biodiesel production in co-solvent media

(2012) Zi Jin et al.   BIORESOURCE TECHNOLOGY

tRNA concentration fine tunes protein solubility

(2012) Ivan Fedyunin et al.   FEBS LETTERS

Ribosome Deficiency Protects Against ER Stress in Saccharomyces cerevisiae

(2012) K. K. Steffen et al.   GENETICS

Protein secretion in Pichia pastoris and advances in protein production

(2011) Leonardo M. Damasceno et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Effect of codon optimization on the expression of Trichoderma reesei endoglucanase 1 in Pichia pastoris

(2011) Gunseli Bayram Akcapinar et al.   BIOTECHNOLOGY PROGRESS

Sequential deletion of Pichia pastoris genes by a self-excisable cassette

(2011) Rongqing Pan et al.   FEMS YEAST RESEARCH

Cotranslational Folding Increases GFP Folding Yield

(2010) Krastyu G. Ugrinov et al.   BIOPHYSICAL JOURNAL

Directionality in protein fold prediction

(2010) Jonathan J Ellis et al.   BMC BIOINFORMATICS

Protein folding on the ribosome

(2010) Lisa D Cabrita et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

Synonymous codon usage influences the local protein structure observed

(2010) Rhodri Saunders et al.   NUCLEIC ACIDS RESEARCH

A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

(2010) Thomas Wild et al.   PLOS BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays

(2009) Joshua S Bloom et al.   BMC GENOMICS

Genome sequence of the recombinant protein production host Pichia pastoris

(2009) Kristof De Schutter et al.   NATURE BIOTECHNOLOGY

Transient ribosomal attenuation coordinates protein synthesis and co-translational folding

(2009) Gong Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Generic Algorithm to Predict the Speed of Translational Elongation: Implications for Protein Biogenesis

(2009) Gong Zhang et al.   PLoS One

Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

(2008) Kristan K. Steffen et al.   CELL

Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

(2008) Brigitte Gasser et al.   Microbial Cell Factories

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

A pause for thought along the co-translational folding pathway

(2008) Anton A. Komar   TRENDS IN BIOCHEMICAL SCIENCES