Metabolic regulatory mechanisms and physiological roles of functional amino acids and their applications in yeast

Accumulation of intracellular S -adenosylmethionine increases the fermentation rate of bottom-fermenting brewer's yeast during high-gravity brewing

(2018) Mayu Oomuro et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

High-level production of valine by expression of the feedback inhibition-insensitive acetohydroxyacid synthase in Saccharomyces cerevisiae

(2018) Natthaporn Takpho et al.   METABOLIC ENGINEERING

A Novel Mitochondrial Serine O-Acetyltransferase, OpSAT1, Plays a Critical Role in Sulfur Metabolism in the Thermotolerant Methylotrophic Yeast Ogataea parapolymorpha

(2018) Ji Yoon Yeon et al.   Scientific Reports

Novel metabolic and physiological functions of branched chain amino acids: a review

(2017) Shihai Zhang et al.   Journal of Animal Science and Biotechnology

Isolation of baker's yeast mutants with proline accumulation that showed enhanced tolerance to baking-associated stresses

(2016) Ariunzaya Tsolmonbaatar et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

StimulatingS-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK

(2016) Takafumi Ogawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proline accumulation protectsSaccharomyces cerevisiaecells in stationary phase from ethanol stress by reducing reactive oxygen species levels

(2016) Hiroshi Takagi et al.   YEAST

Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-l-methionine production

(2016) Kenshi Hayakawa et al.   AMB Express

Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans

(2015) Clare Edwards et al.   BMC GENETICS

Structure-based molecular design for thermostabilization ofN-acetyltransferase Mpr1 involved in a novel pathway of l-arginine synthesis in yeast

(2015) Ryo Nasuno et al.   JOURNAL OF BIOCHEMISTRY

Isolation and characterization of awamori yeast mutants with l -leucine accumulation that overproduce isoamyl alcohol

(2015) Hiroshi Takagi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Finding of thiosulfate pathway for synthesis of organic sulfur compounds in Saccharomyces cerevisiae and improvement of ethanol production

(2015) Eri Funahashi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

13C-metabolic flux analysis in S-adenosyl-l-methionine production by Saccharomyces cerevisiae

(2015) Kenshi Hayakawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

(2015) Markus Schosserer et al.   Nature Communications

Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders

(2014) L. C. Burrage et al.   HUMAN MOLECULAR GENETICS

Novel Cysteine-Centered Sulfur Metabolic Pathway in the Thermotolerant Methylotrophic Yeast Hansenula polymorpha

(2014) Min Jeong Sohn et al.   PLoS One

Nitric Oxide-Mediated Antioxidative Mechanism in Yeast through the Activation of the Transcription Factor Mac1

(2014) Ryo Nasuno et al.   PLoS One

Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging

(2014) Mario G. Mirisola et al.   PLoS Genetics

Initial Volatile Aroma Profiles of Young and Aged Awamori Shochu Determined by GC/MS/Pulsed FPD

(2013) Junsei TAIRA et al.   FOOD SCIENCE AND TECHNOLOGY RESEARCH

Independent and Additive Effects of Glutamic Acid and Methionine on Yeast Longevity

(2013) Ziyun Wu et al.   PLoS One

Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism

(2013) R. Nasuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adenosine kinase-deficient mutant of Saccharomyces cerevisiae accumulates S-adenosylmethionine because of an enhanced methionine biosynthesis pathway

(2012) Muneyoshi Kanai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The flavoprotein Tah18-dependent NO synthesis confers high-temperature stress tolerance on yeast cells

(2012) Akira Nishimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Analysis of the C-Terminal Region of γ-Glutamyl Kinase ofSaccharomyces cerevisiae

(2012) Tomohiro KAINO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae

(2012) Dawid Brat et al.   Biotechnology for Biofuels

Nitrogen requirements of commercial wine yeast strains during fermentation of a synthetic grape must

(2012) Alicia Gutiérrez et al.   FOOD MICROBIOLOGY

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae

(2012) P. O. Ljungdahl et al.   GENETICS

Simultaneous accumulation of proline and trehalose in industrial baker's yeast enhances fermentation ability in frozen dough

(2012) Yu Sasano et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Enhancement of the proline and nitric oxide synthetic pathway improves fermentation ability under multiple baking-associated stress conditions in industrial baker's yeast

(2012) Yu Sasano et al.   Microbial Cell Factories

GABA metabolism pathway genes, UGA1 and GAD1, regulate replicative lifespan in Saccharomyces cerevisiae

(2011) Yuka Kamei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proline accumulation in baker's yeast enhances high-sucrose stress tolerance and fermentation ability in sweet dough

(2011) Yu Sasano et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

An antioxidative mechanism mediated by the yeast N-acetyltransferase Mpr1: oxidative stress-induced arginine synthesis and its physiological role

(2010) Akira Nishimura et al.   FEMS YEAST RESEARCH

Antioxidant N-acetyltransferase Mpr1/2 of industrial baker's yeast enhances fermentation ability after air-drying stress in bread dough

(2010) Yu Sasano et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The l-Cysteine/l-Cystine Shuttle System Provides Reducing Equivalents to the Periplasm in Escherichia coli

(2010) Iwao Ohtsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and amino acid homeostasis are required for chronological longevity inSaccharomyces cerevisiae

(2009) Ashley L. Alvers et al.   AGING CELL

Fermentative production of branched chain amino acids: a focus on metabolic engineering

(2009) Jin Hwan Park et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Stress-tolerance of baker's-yeast (Saccharomyces cerevisiae) cells: stress-protective molecules and genes involved in stress tolerance

(2009) Jun Shima et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Engineering of the yeast antioxidant enzyme Mpr1 for enhanced activity and stability

(2009) Kaoru Iinoya et al.   BIOTECHNOLOGY AND BIOENGINEERING

Suppression of Protein Aggregation by L-Arginine

(2009) Christian Lange et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Proline accumulation in plants: a review

(2008) Nathalie Verbruggen et al.   AMINO ACIDS

Self-Cloning Baker's Yeasts That Accumulate Proline Enhance Freeze Tolerance in Doughs

(2008) T. Kaino et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Ehrlich Pathway for Fusel Alcohol Production: a Century of Research on Saccharomyces cerevisiae Metabolism

(2008) L. A. Hazelwood et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Gene expression profiles and intracellular contents of stress protectants in Saccharomyces cerevisiae under ethanol and sorbitol stresses

(2008) Tomohiro Kaino et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Proline as a stress protectant in yeast: physiological functions, metabolic regulations, and biotechnological applications

(2008) Hiroshi Takagi   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

ROS accumulation and oxidative damage to cell structures in Saccharomyces cerevisiae wine strains during fermentation of high-sugar-containing medium

(2008) Sara Landolfo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Distribution ofL-Azetidine-2-carboxylateN-Acetyltransferase in Yeast

(2008) Masaru WADA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Nitric oxide accumulation is required to protect against iron-mediated oxidative stress in frataxin-deficient Arabidopsis plants

(2008) Mariana Martin et al.   FEBS LETTERS

Possible roles of vacuolar H+-ATPase and mitochondrial function in tolerance to air-drying stress revealed by genome-wide screening ofSaccharomyces cerevisiae deletion strains

(2008) Jun Shima et al.   YEAST

Antioxidative defence alterations in skeletal muscle during prolonged acclimation to cold: role of L-arginine/NO-producing pathway

(2007) V. Petrovic et al.   JOURNAL OF EXPERIMENTAL BIOLOGY