Identification of Noninvasive Biomarkers for Nephrotoxicity Using HK-2 Human Kidney Epithelial Cells

HER2 induces expression of leptin in human breast epithelial cells

(2013) Yujin Cha et al.   BMB Reports

Identification of annexin II as a novel secretory biomarker for breast cancer

(2013) You Rim Jeon et al.   PROTEOMICS

Drug-Induced Nephrotoxicity and Its Biomarkers

(2012) Sun-Young Kim et al.   Biomolecules & Therapeutics

The role of proteomics in prostate cancer research: Biomarker discovery and validation

(2012) Elisa Pin et al.   CLINICAL BIOCHEMISTRY

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

(2011) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Applications of urinary proteomics in biomarker discovery

(2011) Chen Shao et al.   Science China-Life Sciences

Comparison of the novel HK-2 human renal proximal tubular cell line with the standard LLC-PK1 cell line in studying drug-induced nephrotoxicity

(2010) Patrina Gunness et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

HK-2 Human Renal Proximal Tubule Cells as a Model for G Protein–Coupled Receptor Kinase Type 4–Mediated Dopamine 1 Receptor Uncoupling

(2010) John J. Gildea et al.   HYPERTENSION

Analysis of Secreted Proteins as anin vitroModel for Discovery of Liver Toxicity Markers

(2010) John A. Lewis et al.   JOURNAL OF PROTEOME RESEARCH

Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of disease-specific biomarkers

(2010) Paul Dowling et al.   PROTEOMICS

Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity

(2010) Dana Hoffmann et al.   TOXICOLOGY

Validation of reference gene stability for APAP hepatotoxicity studies in different in vitro systems and identification of novel potential toxicity biomarkers

(2010) Bridget C. Fox et al.   TOXICOLOGY IN VITRO

Inhibition of p38-MAPK Potentiates Cisplatin-Induced Apoptosis via GSH Depletion and Increases Intracellular Drug Accumulation in Growth-Arrested Kidney Tubular Epithelial Cells

(2009) Maria Elena Rodríguez-García et al.   TOXICOLOGICAL SCIENCES

Impact of biomarker development on drug safety assessment

(2009) Estelle Marrer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

The cancer secretome: a reservoir of biomarkers

(2008) Hua Xue et al.   Journal of Translational Medicine

Evaluation of Putative Biomarkers of Nephrotoxicity after Exposure to Ochratoxin A In Vivo and In Vitro

(2008) Eva Rached et al.   TOXICOLOGICAL SCIENCES