Telomere attrition: metabolic regulation and signalling function?

Ultra-long telomeres shorten with age in nestling great tits but are static in adults and mask attrition of short telomeres

(2019) Els Atema et al.   Molecular Ecology Resources

Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD)

(2018) Wanil Kim et al.   DIFFERENTIATION

Correlation between telomerase and mTOR pathway in cancer stem cells

(2018) Fatma Dogan et al.   GENE

Do glucocorticoids mediate the link between environmental conditions and telomere dynamics in wild vertebrates? A review

(2018) Frédéric Angelier et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Do Seasonal Glucocorticoid Changes Depend on Reproductive Investment? A Comparative Approach in Birds

(2018) Stefania Casagrande et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Telomere elongation during early development is independent of environmental temperatures in Atlantic salmon

(2018) Darryl McLennan et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells

(2018) Kalpana Gopalakrishnan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Why are there associations between telomere length and behaviour?

(2018) Melissa Bateson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing

(2018) Andrew J. Young   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Comparison of telomere length measurement methods

(2018) Tsung-Po Lai et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Somatic growth and telomere dynamics in vertebrates: relationships, mechanisms and consequences

(2018) Pat Monaghan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The relationship between telomere length and mortality risk in non-model vertebrate systems: a meta-analysis

(2018) Rachael V. Wilbourn et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The lingering impact of stress: brief acute glucocorticoid exposure has sustained, dose-dependent effects on reproduction

(2018) Maren N. Vitousek et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Enzymatic antioxidants but not baseline glucocorticoids mediate the reproduction–survival trade-off in a wild bird

(2018) Stefania Casagrande et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Shorter juvenile telomere length is associated with higher survival to spawning in migratory Atlantic salmon

(2017) Darryl McLennan et al.   FUNCTIONAL ECOLOGY

Spatio-temporal variation in lifelong telomere dynamics in a long-term ecological study

(2017) Lewis G. Spurgin et al.   JOURNAL OF ANIMAL ECOLOGY

Telomere attrition and growth: a life-history framework and case study in common terns

(2017) O. Vedder et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Kinship and familiarity mitigate costs of social conflict between Seychelles warbler neighbors

(2017) Kat Bebbington et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective disappearance of great tits with short telomeres in urban areas

(2017) Pablo Salmón et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Detecting telomere elongation in longitudinal datasets: analysis of a proposal by Simons, Stulp and Nakagawa

(2017) Daniel Nettle et al.   PeerJ

Early-life adversity accelerates cellular ageing and affects adult inflammation: Experimental evidence from the European starling

(2017) Daniel Nettle et al.   Scientific Reports

Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field

(2016) Maya B. Mathur et al.   BRAIN BEHAVIOR AND IMMUNITY

Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin

(2016) Jigar N. Bandaria et al.   CELL

Do Hormones, Telomere Lengths, and Oxidative Stress form an Integrated Phenotype? A Case Study in Free-Living Tree Swallows

(2016) J. Q. Ouyang et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Telomere dynamics in free-living edible dormice (Glis glis): the impact of hibernation and food supply

(2016) Franz Hoelzl et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Telomere length reflects reproductive effort indicated by corticosterone levels in a long-lived seabird

(2016) Christina Bauch et al.   MOLECULAR ECOLOGY

Danazol Treatment for Telomere Diseases

(2016) Danielle M. Townsley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer

(2016) Wanil Kim et al.   PLOS BIOLOGY

Nuclear respiratory factor 1 and endurance exercise promote human telomere transcription

(2016) A. Diman et al.   Science Advances

Telomeres are elongated in older individuals in a hibernating rodent, the edible dormouse (Glis glis)

(2016) Franz Hoelzl et al.   Scientific Reports

Questioning causal involvement of telomeres in aging

(2015) Mirre J.P. Simons   AGEING RESEARCH REVIEWS

Lifelong leukocyte telomere dynamics and survival in a free-living mammal

(2015) Jennifer Fairlie et al.   AGING CELL

Telomere dynamics may link stress exposure and ageing across generations

(2015) Mark F. Haussmann et al.   Biology Letters

Repeated stressors in adulthood increase the rate of biological ageing

(2015) Michaela Hau et al.   Frontiers in Zoology

Urbanization, oxidative stress and inflammation: a question of evolving, acclimatizing or coping with urban environmental stress

(2015) Caroline Isaksson   FUNCTIONAL ECOLOGY

Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres

(2015) C. Bar et al.   HAEMATOLOGICA

Commentary: The reliability of telomere length measurements

(2015) Simon Verhulst et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients

(2015) K. Simpson et al.   Molecular Oncology

Regulation of mammalian nucleotide metabolism and biosynthesis

(2015) Andrew N. Lane et al.   NUCLEIC ACIDS RESEARCH

Hidden costs of infection: Chronic malaria accelerates telomere degradation and senescence in wild birds

(2015) M. Asghar et al.   SCIENCE

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

(2015) E. H. Blackburn et al.   SCIENCE

Understanding stress in the healthy animal – potential paths for progress

(2015) L. Michael Romero et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Regulation of nucleotide metabolism by mutant p53 contributes to its gain-of-function activities

(2015) Madhusudhan Kollareddy et al.   Nature Communications

Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres

(2015) C. Bar et al.   HAEMATOLOGICA

Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity

(2015) Emilio Cusanelli et al.   Frontiers in Genetics

Migration and stress during reproduction govern telomere dynamics in a seabird

(2014) J. Schultner et al.   Biology Letters

Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances

(2014) Jérôme D. Robin et al.   GENES & DEVELOPMENT

Where is mTOR and what is it doing there?

(2014) Charles Betz et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids

(2014) Martin Picard et al.   Nature Reviews Endocrinology

Transcriptional outcome of telomere signalling

(2014) Jing Ye et al.   NATURE REVIEWS GENETICS

Maternal Effects Underlie Ageing Costs of Growth in the Zebra Finch (Taeniopygia guttata)

(2014) Mathilde L. Tissier et al.   PLoS One

Experimental Food Restriction Reveals Individual Differences in Corticosterone Reaction Norms with No Oxidative Costs

(2014) Ádám Z. Lendvai et al.   PLoS One

Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources

(2014) A. Zalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental telomere attrition predicts impulsive decision-making in adult starlings

(2014) M. Bateson et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird

(2014) K. A. Herborn et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds

(2014) J. J. Boonekamp et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes

(2014) Isabel López de Silanes et al.   Nature Communications

Measuring telomere length and telomere dynamics in evolutionary biology and ecology

(2014) Daniel H. Nussey et al.   Methods in Ecology and Evolution

Telomere length behaves as biomarker of somatic redundancy rather than biological age

(2013) Jelle J. Boonekamp et al.   AGING CELL

Growth or longevity: the TOR’s decision on lifespan regulation

(2013) Yuehua Wei et al.   BIOGERONTOLOGY

A statistical approach to distinguish telomere elongation from error in longitudinal datasets

(2013) Mirre J. P. Simons et al.   BIOGERONTOLOGY

Seasonal variation in telomere length of a hibernating rodent

(2013) C. Turbill et al.   Biology Letters

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Nature vs nurture: Interplay between the genetic control of telomere length and environmental factors

(2013) Yaniv Harari et al.   CELL CYCLE

Starting with a handicap: phenotypic differences between early- and late-born king penguin chicks and their survival correlates

(2013) Antoine Stier et al.   FUNCTIONAL ECOLOGY

Alternative lengthening of telomeres in normal mammalian somatic cells

(2013) A. A. Neumann et al.   GENES & DEVELOPMENT

Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

(2013) A. Gupta et al.   GENETICS

Testosterone: a metabolic hormone in health and disease

(2013) Daniel M Kelly et al.   JOURNAL OF ENDOCRINOLOGY

Telomeric Noncoding RNA TERRA Is Induced by Telomere Shortening to Nucleate Telomerase Molecules at Short Telomeres

(2013) Emilio Cusanelli et al.   MOLECULAR CELL

The telomere lengthening conundrum—artifact or biology?

(2013) Troels Steenstrup et al.   NUCLEIC ACIDS RESEARCH

Telomere Length Correlations among Somatic Tissues in Adult Zebra Finches

(2013) Sophie Reichert et al.   PLoS One

Telomeres shorten at equivalent rates in somatic tissues of adults

(2013) Lily Daniali et al.   Nature Communications

Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence

(2013) Katherine M. Aird et al.   Cell Reports

TOR links starvation responses to telomere length maintenance

(2012) Martin Kupiec et al.   CELL CYCLE

Life history and the ecology of stress: how do glucocorticoid hormones influence life-history variation in animals?

(2012) Erica J. Crespi et al.   FUNCTIONAL ECOLOGY

Exercise alters mRNA expression of telomere-repeat binding factor 1 in skeletal muscle via p38 MAPK

(2012) Andrew T. Ludlow et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress

(2012) Wayne R. Austin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Exercise Modifies Age-Related Telomere Dynamics in a Tissue-Specific Fashion

(2012) Andrew T. Ludlow et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Testosterone regulation of Akt/mTORC1/FoxO3a signaling in skeletal muscle

(2012) James P. White et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Telomere length and dynamics predict mortality in a wild longitudinal study

(2012) Emma L. B. Barrett et al.   MOLECULAR ECOLOGY

Axis of ageing: telomeres, p53 and mitochondria

(2012) Ergün Sahin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Telomere length regulates TERRA levels through increased trimethylation of telomeric H3K9 and HP1α

(2012) Nausica Arnoult et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomere length in early life predicts lifespan

(2012) B. J. Heidinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Telomere length reflects phenotypic quality and costs of reproduction in a long-lived seabird

(2012) C. Bauch et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

TERRA Promotes Telomere Shortening through Exonuclease 1–Mediated Resection of Chromosome Ends

(2012) Verena Pfeiffer et al.   PLoS Genetics

Tor Complex 1 Controls Telomere Length by Affecting the Level of Ku

(2011) Lior Ungar et al.   CURRENT BIOLOGY

Catching-up but telomere loss: half-opening the black box of growth and ageing trade-off in wild king penguin chicks

(2011) SYLVIE GEIGER et al.   MOLECULAR ECOLOGY

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Effects of Individual Pre-Fledging Traits and Environmental Conditions on Return Patterns in Juvenile King Penguins

(2011) Claire Saraux et al.   PLoS One

Embryonic exposure to corticosterone modifies the juvenile stress response, oxidative stress and telomere length

(2011) M. F. Haussmann et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Telomeres and life histories: the long and the short of it

(2010) Pat Monaghan   Annals of the New York Academy of Sciences

Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline

(2010) Jue Lin et al.   BRAIN RESEARCH

Telomere biology in Metazoa

(2010) Nuno M.V. Gomes et al.   FEBS LETTERS

Oxidative stress as a life-history constraint: the role of reactive oxygen species in shaping phenotypes from conception to death

(2010) Neil B. Metcalfe et al.   FUNCTIONAL ECOLOGY

AMPK Regulates Metabolic Actions of Glucocorticoids by Phosphorylating the Glucocorticoid Receptor through p38 MAPK

(2010) Nancy Nader et al.   MOLECULAR ENDOCRINOLOGY

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

(2010) Zhaohui Feng et al.   TRENDS IN CELL BIOLOGY

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress

(2009) Natascia Ventura et al.   AGING CELL

Stress Response and the Value of Reproduction: Are Birds Prudent Parents?

(2009) Veronika Bókony et al.   AMERICAN NATURALIST

Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells

(2009) R. T. Calado et al.   BLOOD

AMPK as a mediator of hormonal signalling

(2009) Chung Thong Lim et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri

(2009) Nils Hartmann et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Telomere dynamics rather than age predict life expectancy in the wild

(2009) P. Bize et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Rodents for comparative aging studies: from mice to beavers

(2008) Vera Gorbunova et al.   AGE

Amino acid regulation of TOR complex 1

(2008) Joseph Avruch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduced telomerase activity in human T lymphocytes exposed to cortisol

(2008) Jenny Choi et al.   BRAIN BEHAVIOR AND IMMUNITY

Oxidative stress in ecology and evolution: lessons from avian studies

(2008) David Costantini   ECOLOGY LETTERS

Oxidative stress as a mediator of life history trade-offs: mechanisms, measurements and interpretation

(2008) Pat Monaghan et al.   ECOLOGY LETTERS

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

(2008) S. Ahmed et al.   JOURNAL OF CELL SCIENCE

Telomeric position effect: From the yeast paradigm to human pathologies?

(2007) Alexandre Ottaviani et al.   BIOCHIMIE