Copper-Catalyzed 1,2-Bistrifluoromethylation of Terminal Alkenes

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Multicomponent Oxidative Trifluoromethylation of Alkynes with Photoredox Catalysis: Synthesis of α-Trifluoromethyl Ketones

(2018) Yashwardhan R. Malpani et al.   ORGANIC LETTERS

Cu-catalyzed chlorotrifluoromethylation of alkenes with CF3SO2Cl

(2018) Wei Zhang et al.   JOURNAL OF FLUORINE CHEMISTRY

Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals

(2017) Lianqian Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Photoredox-Catalyzed Chlorotrifluoromethylation of Alkynes: Synthesis of Tetrasubstituted Alkenes

(2017) Hong Sik Han et al.   ORGANIC LETTERS

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

(2016) Yu Zhou et al.   CHEMICAL REVIEWS

The unique fluorine effects in organic reactions: recent facts and insights into fluoroalkylations

(2016) Chuanfa Ni et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process

(2016) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Intermolecular Chloro- and Bromotrifluoromethylation of Alkenes

(2016) Mingyang Fu et al.   ORGANIC LETTERS

An Efficient and Practical Method for Olefin Dihydroxylation

(2016) Zhi-bin Luo et al.   SYNTHESIS-STUTTGART

Copper-Mediated Halotrifluoromethylation of Unactivated Alkenes

(2015) Won An et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver-Mediated Oxidative Fluorotrifluoromethylation of Unactivated Alkenes

(2015) Wei Yu et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Trifluoromethylazidation of Alkynes: Efficient Access to CF3-Substituted Azirines and Aziridines

(2015) Fei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Mediated Oxidative Trifluoromethylation of Phenols: Direct Synthesis of Aryl Trifluoromethyl Ethers

(2015) Jian-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Copper-Promoted Trifluoromethanesulfonylation and Trifluoromethylation of Arenediazonium Tetrafluoroborates with NaSO2CF3

(2015) Ke Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Intermolecular Trifluoromethylazidation and Trifluoromethylthiocyanation of Allenes: Efficient Access to CF3-Containing Allyl Azides and Thiocyanates

(2015) Na Zhu et al.   ORGANIC LETTERS

Copper-Catalyzed Intermolecular Trifluoromethylthiocyanation of Alkenes: Convenient Access to CF3-Containing Alkyl Thiocyanates

(2015) Zhaoli Liang et al.   ORGANIC LETTERS

Copper-Mediated Radical 1,2-Bis(trifluoromethylation) of Alkenes with Sodium Trifluoromethanesulfinate

(2015) Bin Yang et al.   ORGANIC LETTERS

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Recent Advances in Trifluoromethylation Reactions with Electrophilic Trifluoromethylating Reagents

(2014) Sebastián Barata-Vallejo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Catalyzed Three-Component Azidotrifluoromethylation/Difunctionalization of Alkenes

(2014) Mingbo Yang et al.   CHINESE JOURNAL OF CHEMISTRY

Recent progress in transition-metal-catalyzed trifluoromethylation of olefins using electrophilic CF3 reagents

(2014) Takashi Koike et al.   JOURNAL OF FLUORINE CHEMISTRY

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

(2014) Wei Zhu et al.   JOURNAL OF FLUORINE CHEMISTRY

Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with (TMS)CF3: Construction of Trifluoromethylated Azaheterocycles

(2014) Jin-Shun Lin et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Intermolecular Trifluoromethylarylation of Alkenes: Mutual Activation of Arylboronic Acid and CF3+ Reagent

(2014) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in trifluoromethylation of organic compounds using Umemoto's reagents

(2014) Cai Zhang   ORGANIC & BIOMOLECULAR CHEMISTRY

Vicinal Difunctionalization of Alkenes: Chlorotrifluoromethylation with CF3SO2Cl by Photoredox Catalysis

(2014) Se Hwan Oh et al.   ORGANIC LETTERS

Copper-Catalyzed Intermolecular Aminoazidation of Alkenes

(2014) Bo Zhang et al.   ORGANIC LETTERS

Iodotrifluoromethylation of Alkenes and Alkynes with Sodium Trifluoromethanesulfinate and Iodine Pentoxide

(2014) Zhaojia Hang et al.   ORGANIC LETTERS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

A “Renaissance” in Radical Trifluoromethylation

(2012) Armido Studer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes

(2012) Rong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxytrifluoromethylation of multiple bonds using copper catalyst under mild conditions

(2012) Hiromichi Egami et al.   TETRAHEDRON LETTERS

Aromatic Trifluoromethylation with Metal Complexes

(2011) Olesya A. Tomashenko et al.   CHEMICAL REVIEWS

Palladium-Catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature

(2011) Xin Mu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Direct C–H Oxidative Trifluoromethylation of Heteroarenes

(2011) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Silver-Mediated Trifluoromethylation of Arenes Using TMSCF3

(2011) Yingda Ye et al.   ORGANIC LETTERS

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Facilitating the Design of Fluorinated Drugs

(2009) Klaus Müller et al.   CHEMISTRY & BIOLOGY

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Oxidation by permanganate: synthetic and mechanistic aspects

(2008) Sukalyan Dash et al.   TETRAHEDRON

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS