Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet

(2018) Christine A. Olson et al.   CELL

Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders

(2018) Katrin Augustin et al.   LANCET NEUROLOGY

Decreased number and increased volume with mitochondrial enlargement of cerebellar synaptic terminals in a mouse model of chronic demyelination

(2018) Huy Bang Nguyen et al.   Medical Molecular Morphology

Physiological changes in neurodegeneration — mechanistic insights and clinical utility

(2018) Rebekah M. Ahmed et al.   Nature Reviews Neurology

Do ketone bodies mediate the anti-seizure effects of the ketogenic diet?

(2018) Timothy A. Simeone et al.   NEUROPHARMACOLOGY

Oligodendrocytes in the Mouse Corpus Callosum Maintain Axonal Function by Delivery of Glucose

(2018) Niklas Meyer et al.   Cell Reports

Neuronal Lipid Metabolism: Multiple Pathways Driving Functional Outcomes in Health and Disease

(2018) Timothy J. Tracey et al.   Frontiers in Molecular Neuroscience

Brain Diffusion Imaging and Tractography to Distinguish Clinical Severity of Human PLP1-Related Disorders

(2018) Catherine Sarret et al.   DEVELOPMENTAL NEUROSCIENCE

Cognitive benefits of the ketogenic diet in patients with epilepsy: A systematic overview

(2018) Annemiek A. van Berkel et al.   EPILEPSY & BEHAVIOR

Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy

(2018) R. Fledrich et al.   Nature Communications

Ketogenic diets attenuate cyclooxygenase and lipoxygenase gene expression in multiple sclerosis

(2018) Markus Bock et al.   EBioMedicine

Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

(2017) Stefan A. Berghoff et al.   Nature Communications

Monitoring ATP dynamics in electrically active white matter tracts

(2017) Andrea Trevisiol et al.   eLife

Blood-brain barrier hyperpermeability precedes demyelination in the cuprizone model

(2017) Stefan A. Berghoff et al.   Acta Neuropathologica Communications

The magnetic resonance imaging spectrum of Pelizaeus–Merzbacher disease: A multicenter study of 19 patients

(2016) Kaoru Sumida et al.   BRAIN & DEVELOPMENT

Pediatric reference data of serum lipids and prevalence of dyslipidemia: Results from a population-based cohort in Germany

(2016) Anne Dathan-Stumpf et al.   CLINICAL BIOCHEMISTRY

Time-course of myelination and atrophy on cerebral imaging in 35 patients withPLP1-related disorders

(2016) Catherine Sarret et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

(2016) Aiman S. Saab et al.   NEURON

Novel pathologic findings in patients with Pelizaeus-Merzbacher disease

(2016) Jeremy J. Laukka et al.   NEUROSCIENCE LETTERS

LXR Regulation of Brain Cholesterol: From Development to Disease

(2016) Rebecca Courtney et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

(2016) In Young Choi et al.   Cell Reports

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

(2015) Dania C. Liemburg-Apers et al.   ARCHIVES OF TOXICOLOGY

The ketogenic diet compensates for AGC1 deficiency and improves myelination

(2015) Maria Dahlin et al.   EPILEPSIA

Modeling the natural history of Pelizaeus–Merzbacher disease

(2015) Joshua A. Mayer et al.   NEUROBIOLOGY OF DISEASE

Cellular and molecular neuropathology of the cuprizone mouse model: Clinical relevance for multiple sclerosis

(2014) Jelle Praet et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Pelizaeus-Merzbacher disease: Cellular pathogenesis and pharmacologic therapy

(2014) Tomohiro Torii et al.   PEDIATRICS INTERNATIONAL

Disruption of Myelin Leads to Ectopic Expression of KV1.1 Channels with Abnormal Conductivity of Optic Nerve Axons in a Cuprizone-Induced Model of Demyelination

(2014) Bandita Bagchi et al.   PLoS One

Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging

(2013) M. Picard et al.   DIABETES

Alterations of brain eicosanoid synthetic pathway in multiple sclerosis and in animal models of demyelination: Role of cyclooxygenase-2

(2013) Sara Palumbo et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Cholesterol homeostasis: a key to prevent or slow down neurodegeneration

(2013) Laura Anchisi et al.   Frontiers in Physiology

Assessment of myelination in hypomyelinating disorders by quantitative MRI

(2012) Steffi F. Dreha-Kulaczewski et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

(2012) Gesine Saher et al.   NATURE MEDICINE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The metabolic efficiency of myelinated vs unmyelinated axons

(2011) Ali M Neishabouri et al.   BMC NEUROSCIENCE

Smith–Lemli–Opitz syndrome

(2011) Andrea E. DeBarber et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Axon-glial interaction in the CNS: what we have learned from mouse models of Pelizaeus-Merzbacher disease

(2011) Fredrik I. Gruenenfelder et al.   JOURNAL OF ANATOMY

Targeted metabolomic analyses of cellular models of pelizaeus-merzbacher disease reveal plasmalogen and myo-inositol solute carrier dysfunction

(2011) Paul L Wood et al.   Lipids in Health and Disease

Inhibition of 5-lipoxygenase activity in mice during cuprizone-induced demyelination attenuates neuroinflammation, motor dysfunction and axonal damage

(2011) K. Yoshikawa et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

(2010) Julia M. Edgar et al.   EMBO Molecular Medicine

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

Modeling the influence of TR and excitation flip angle on the magnetization transfer ratio (MTR) in human brain obtained from 3D spoiled gradient echo MRI

(2010) Gunther Helms et al.   MAGNETIC RESONANCE IN MEDICINE

Cholesterol Regulates the Endoplasmic Reticulum Exit of the Major Membrane Protein P0 Required for Peripheral Myelin Compaction

(2009) G. Saher et al.   JOURNAL OF NEUROSCIENCE

The molecular and cellular defects underlying Pelizaeus–Merzbacher disease

(2008) Karen J. Woodward   EXPERT REVIEWS IN MOLECULAR MEDICINE

Increase in mitochondrial density within axons and supporting cells in response to demyelination in thePlp1mouse model

(2008) Vanessa Hogan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

High-resolution maps of magnetization transfer with inherent correction for RF inhomogeneity andT1relaxation obtained from 3D FLASH MRI

(2008) Gunther Helms et al.   MAGNETIC RESONANCE IN MEDICINE

Quantitative FLASH MRI at 3T using a rational approximation of the Ernst equation

(2008) Gunther Helms et al.   MAGNETIC RESONANCE IN MEDICINE